A convenient and simple PdCl2-based hydrogenation catalyst has been developed. The liquid, air, and moisture stable precursor is pumped into the reactor where it is temporarily immobilized and reduced on the channel surface into Pd(0), providing a constant high activity for hydrogenation reaction. The catalyst is leached with time, avoiding any kind of clogging problems during long time runs.
1. McQuade, D. T.; Seeberger, P. H.J. Org. Chem. 2013, 78, 6384–6389.
McQuade, D. T.; Seeberger, P. H.J. Org. Chem. 2013, 78, 6384–6389.)| false