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  • 1 Universidade Federal do Rio de Janeiro, Rio de Janeiro, Bloco A 622, RJ 21941—909, Brazil
  • 2 Universidade Federal do Rio Grande do Sul, Faculty of Pharmacy,, Av. Ipiranga, 2752, Porto Alegre-RS, 90610—000, Brazil
  • 3 Faculty of Pharmacy, Budapest 1031, Brazil
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The use of continuous-flow chemistry has shown to be an important tool in improving API manufacture. In the present paper, we report the use of continuous-flow reactors in the synthesis of the bicyclic side chain of antiretroviral Darunavir.

Supplementary Materials

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