Journal of Flow Chemistry
Volume/Issue:
Volume 6: Issue 1
Application of enzyme-immobilization technique for microflow reactor
Authors:
Hiroshi Yamaguchi Tokai University, Kawayo, Minamiaso, Kumamoto 869–1404, Japan

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Takeshi Honda Yamaguchi University School of Medicine, 1-1-1 Minami-ogushi, Ube, Yamaguchi 755–8505, Japan

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Masaya Miyazaki Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka 816–8580, Japan
National Institute of Advanced Industrial Science and Technology, 807-1 Shuku, Tosu, Saga 841–0052, Japan

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Pages:
13–17
Online Publication Date:
Mar 2016
Publication Date:
01 Mar 2016
Article Category:
Review Article
DOI:
https://doi.org/10.1556/1846.2015.00039
Keywords:
microreactor; enzyme; immobilization; biotransformation
Restricted access

The microreaction technology which is an interdisciplinary science and engineering, have attracted attention in many fields in the past years. Several microreactors have been developed. Enzyme is one of the catalysts, which is useful in substance production in an environmentally friendly way, and has high potential for the preparation of chiral compounds. These features are suitable for pharmaceutical process. However, not so many enzymatic processes were commercialized, because of problems in stability of enzyme molecule, cost, and efficiency of the reactions. Thus, there have been demands for innovation in process engineering particularly for enzymatic reactions, and microreaction devices can be a strong tool for the development of enzyme processes. In this minireview, we summarize fundamental immobilization techniques to develop enzyme microreactor. Some important applications of this technology toward the chemical processing are also included.

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Cover Journal of Flow Chemistry
Journal of Flow Chemistry A Journal of the Flow Chemistry Society
Print ISSN:
2062-249X
Online ISSN:
2063-0212

To see the editorial board, please visit the website of Springer Nature.

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Journal of Flow Chemistry
Language English
Size A4
Year of
Foundation		 2011
Volumes
per Year		 1
Issues
per Year		 4
Founder Áramlásos Kémiai Tudományos Társaság
Founder's
Address		 H-1031 Budapest, Hungary Záhony utca 7.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2062-249X (Print)
ISSN 2063-0212 (Online)

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