Journal of Flow Chemistry
Volume/Issue:
Volume 6: Issue 1
A microfluidic toolbox for the development of in-situ product removal strategies in biocatalysis
Authors:
Søren Heintz Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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Aleksandar Mitic Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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Rolf H. Ringborg Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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Ulrich Krühne Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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John M. Woodley Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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Krist V. Gernaey Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark

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Pages:
18–26
Online Publication Date:
Mar 2016
Publication Date:
01 Mar 2016
Article Category:
Review Article
DOI:
https://doi.org/10.1556/1846.2015.00040
Keywords:
microfluidics; in-situ product removal (ISPR); process intensification; biocatalysis; process development
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A microfluidic toolbox for accelerated development of biocatalytic processes has great potential. This is especially the case for the development of advanced biocatalytic process concepts, where reactors and product separation methods are closely linked together to intensify the process performance, e.g., by the use of in-situ product removal (ISPR). This review provides a general overview of currently available tools in a microfluidic toolbox and how this toolbox can be applied to the development of advanced biocatalytic process concepts. Emphasis is placed on describing the possibilities and advantages of the microfluidic toolbox that are difficult to achieve with conventional batch-processbased technologies. Application of this microfluidic toolbox will potentially make it possible to intensify biocatalytic reactions and thereby facilitate the development towards novel and advanced biocatalytic processes, which in many cases have proven too difficult in conventional batch equipment.

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Cover Journal of Flow Chemistry
Journal of Flow Chemistry A Journal of the Flow Chemistry Society
Print ISSN:
2062-249X
Online ISSN:
2063-0212

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Journal of Flow Chemistry
Language English
Size A4
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Foundation		 2011
Volumes
per Year		 1
Issues
per Year		 4
Founder Áramlásos Kémiai Tudományos Társaság
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Springer Nature Switzerland AG
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ISSN 2062-249X (Print)
ISSN 2063-0212 (Online)

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