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  • 1 Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
  • 2 University of São Paulo, São Paulo, 05508-000 São Paulo, Brazil
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The confinement of a biocatalyst designed to operate under continuous-flow conditions is a strategy developed by nature in order to achieve efficient reactions in biological media. Herein, we present a mimetic model that employs a confined lipase (CAL-B) in the production of several carboxamide derivatives from esters as precursors. The remarkable selectivity of such system is also described when α,β-unsatured carboxylic substrates are employed.

Supplementary Materials

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