In this Section of the journal, the literature on continuous flow synthesis (primarily organic synthesis and functional materials) from the period of April — June 2016 is presented. All the publications are listed ordered by journal name, with a Review article appearing at the end. In this quarter the number of papers on continuous flow organic synthesis is relatively less as a few special issues are forthcoming. It is interesting to observe that the number of papers on continuous flow oxidation are more than ever before!
J. Zakrzewski , A. P. Smalley, M. A. Kabeshov, M. J. Gaunt, A. A. Lapkin “Continuous Flow Synthesis and Derivatization of Aziridines through Palladium-Catalyzed C(sp3)-H Activation” Angewandte Chemie International Edition 2016, 55, 8878–8883
L. A. Truter , V. Ordomsky, J. C. Schouten, T. A. Nijhuis “The Application of Palladium and Zeolite Incorporated Chip-Based Microreactors” Applied Catalysis A: General 2016, 515, 72–82
S. Santiago-Felipe , L. A. Tortajada-Genaro, J. Carrascosa, R. Puchades, Á. Maquieira “Real-Time Loop-Mediated Isothermal DNA Amplification in Compact Disc Micro-Reactors” Biosensors and Bioelectronics 2016, 79, 300–306
M. Akram , A. T. Saleh, W. A. W. Ibrahim, A. S. Awan, R. Hussain “Continuous Microwave Flow Synthesis (CMFS) of Nano-Sized Tin Oxide: Effect of Precursor Concentration” Ceramics International 2016, 42, 8613–8619
L. A. Truter , J. Juan-Alcañiz, F. Kapteijn, T. A. Nijhuis, J. Gascon, J. C. Schouten “Metal–Organic Framework Capillary Microreactor for Application in Click Chemistry” ChemCatChem 2016, 8, 1692–1698
Q. Deng , R. Shen, R. Ding, L. Zhang “Bromination of Aromatic Compounds Using Bromine in a Microreactor” Chemical Engineering & Technology 2016, 39, 1445–1450
S. O. Dorofeenko , E. V. Polianczyk “Conversion of Hydrocarbon Gases to Synthesis Gas in a Reversed-Flow Filtration Combustion Reactor” Chemical Engineering Journal 2016, 292, 183–189
T. H. Rehm , C. Berguerand, S. Ek, R. Zapf, P. Löb, L. Nikoshvili, L. Kiwi-Minsker “Continuously Operated Falling Film Microreactor for Selective Hydrogenation of Carbon–Carbon Triple Bonds” Chemical Engineering Journal 2016, 293, 345–354
H. Butcher , B. A. Wilhite “Enhancing Catalyst Effectiveness by Increasing Catalyst Film Thickness in Coated-Wall Microreactors: Exploiting Heat Effects in Catalytic Methane Steam Micro-Reformers” Chemical Engineering Science 2016, 143, 47–54
L. Yang , N. Dietrich, K. Loubière, C. Gourdon, G. Hébrard “Visualization and Characterization of Gas–Liquid Mass Transfer around a Taylor Bubble Right after the Formation Stage in Microreactors” Chemical Engineering Science 2016, 143, 364–368
C. A. Castor , A. Pontier, J. Durand, J. C. Pinto, L. Prat “Real Time Monitoring of the Quiescent Suspension Polymerization of Vinyl Chloride in Microreactors –Part 2. A Kinetic Study by Raman Spectroscopy and Evolution of Droplet Size” Chemical Engineering Science 2016, 145, 279–293
B. Gutmann , U. Weigl, D. P. Cox, C. O. Kappe “Batch and Continuous Flow Aerobic Oxidation of 14-Hydroxy Opioids to 1,3-Oxazolidines: A Concise Synthesis of Noroxymorphone” Chemistry –A European Journal 2016, 22, 10393–10398
Z. Liu , T. Wakihara, N. Nomura, T. Matsuo, C. Anand, S. P. Elangovan, Y. Yanaba, T. Yoshikawa, T. Okubo “Ultrafast and Continuous Flow Synthesis of Silicoaluminophosphates” Chemistry of Materials 2016, 28, 4840–4847
C. Bottecchia , N. Erdmann, P. M. A. Tijssen, L.-G. Milroy, L. Brunsveld, V. Hessel, T. Noël “Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis” ChemSusChem 2016, 9, 1781–1785
K. Meller , P. Pomastowski, D. Grzywinski, M. Szumski, B. Buszewski “Preparation and Evaluation of Dual-Enzyme Microreactor with Co-Immobilized Trypsin and Chymotrypsin” Journal of Chromatography A 2016, 1440, 45–54
L. H. Andrade , B. A. Sousa, T. F. Jamison “Confining a Biocatalyst for Highly Efficient and Selective Synthesis of Carboxamide Derivatives under Continuous-Flow Conditions” Journal of Flow Chemistry 2016, 6, 67–72
F. M. Akwi , C. Bosma, P. Watts “A Facile Optimization of Diazotization and Phase Transfer Catalyzed Azo-Coupling Reactions in Microreactors” Journal of Flow Chemistry 2016, 6, 73–79
H. Yalgin , D. Luart, C. Len “First Examples of Doebner-Miller Reaction in Flow: Efficient Production of 2-Methylquinoline Derivatives in Water” Journal of Flow Chemistry 2016, 6, 80–85
G. M. Dezso , S. J. Šimecek, S. S. György, T. Hans-Jürgen Wester, I. Kertész, L. Galuska “Multiparametric Labeling Optimization and Synthesis of 68Ga-Labeled Compounds Applying a Continuous-Flow Microfluidic Methodology” Journal of Flow Chemistry 2016, 6, 86–93
Y. Liu , M. Q. Zhu, X. Z. Chen, U. Jameel, J. G. Lu “Coating of Au–Al2O3 Catalyst in the Wall of Microcapillary and Its Application in Cyclohexane Oxidation” Journal of Flow Chemistry 2016, 6, 110–116
T. Sipocz , L. Lengyel, G. Sipos, L. Kocsis, G. Dormán, R. V. Jones, F. Darvas “Regioselective Catalytic Alkylation of N-Heterocycles in Continuous Flow” Journal of Flow Chemistry 2016, 6, 117–122
M. Cannio , C. Ponzoni, M. L. Gualtieri, E. Lugli, C. Leonelli, M. Romagnoli “Stabilization and Thermal Conductivity of Aqueous Magnetite Nanofluid from Continuous Flows Hydrothermal Microwave Synthesis” Materials Letters 2016, 173, 195–198
T. Vandermeersch , T. R. C. van Assche, J. F. M. Denayer, W. de Malsche “A Continuous Flow Reactor Setup as a Tool for Rapid Synthesis of Micron Sized Naa Zeolite” Microporous and Mesoporous Materials 2016, 226, 133–139
L. A. Truter , V. Ordomsky, J. C. Schouten, T. A. Nijhuis “Zeolite Incorporation in Chip-Based Microreactors” Microporous and Mesoporous Materials 2016, 226, 424–432
G. Niu , M. Zhou, X. Yang, J. Park, N. Lu, J. Wang, M. J. Kim, L. Wang, Y. Xia “Synthesis of Pt–Ni Octahedra in Continuous-Flow Droplet Reactors for the Scalable Production of Highly Active Catalysts toward Oxygen Reduction” Nano Letters 2016, 16, 3850–3857
D. Chandrasekhar , S. Borra, J. B. Nanubolu, R. A. Maurya “Visible Light Driven Photocascade Catalysis: Ru(Bpy)3(PF6)2/TBHP-Mediated Synthesis of Fused ß-Carbolines in Batch and Flow Microreactors” Organic Letters 2016, 18, 2974–2977
S. Bay , T. Baumeister, A. S. K. Hashmi, T. Röder “Safe and Fast Flow Synthesis of Functionalized Oxazoles with Molecular Oxygen in a Microstructured Reactor” Organic Process Research & Development 2016, 20, 1297–1304
Z. Amara , M. Poliakoff, R. Duque, D. Geier, G. Franciò, C. M. Gordon, R. E. Meadows, R. Woodward, W. Leitner “Enabling the Scale-Up of a Key Asymmetric Hydrogenation Step in the Synthesis of an API Using Continuous Flow Solid-Supported Catalysis” Organic Process Research & Development 2016, 20, 1321–1327
H. Kim , K.-I. Min, K. Inoue, D. J. Im, D. P. Kim, J. Yoshida “Submillisecond Organic Synthesis: Outpacing Fries Rearrangement through Microfluidic Rapid Mixing” Science 2016, 352, 691–694
J. Ehgartner , P. Sulzer, T. Burger, A. Kasjanow, D. Bouwes, U. Krühne, I. Klimant, T. Mayr “Online Analysis of Oxygen Inside Silicon-Glass Microreactors with Integrated Optical Sensors” Sensors and Actuators B: Chemical 2016, 228, 748–757
M. T. Alotaibi , M. J. Taylor, D. Liu, S. K. Beaumont, G. Kyriakou “Selective Oxidation of Cyclohexene through Gold Functionalized Silica Monolith Microreactors” Surface Science 2016, 646, 179–185
M. Asadi , J. F. Hooper, D. W. Lupton “Biodiesel Synthesis Using Integrated Acid and Base Catalysis in Continuous Flow” Tetrahedron 2016, 72, 3729–3733
M. Janczarek , E. Kowalska, B. Ohtani “Decahedral-Shaped Anatase Titania Photocatalyst Particles: Synthesis in a Newly Developed Coaxial-Flow Gas-Phase Reactor” Chemical Engineering Journal 2016, 289, 502–512
S. Sharada , P. L. Suryawanshi, R. Kumar, P. S. P. Gumfekar, T. B. Narsaiah, S. H. Sonawane “Synthesis of Palladium Nanoparticles Using Continuous Flow Microreactor” Colloids and Surfaces A: Physicochemical and Engineering Aspects 2016, 498, 297–304
P. Nørby , K.M. Ø. Jensen, N. Lock, M. Christensen, B. B. Iversen “Continuous Flow Supercritical Water Synthesis and Temperature-Dependent Defect Structure Analysis of YAG and YbAG Nanoparticles” Crystal Growth & Design 2016, 16, 2646–2652
M. Harada , C. Cong “Microwave Assisted Polyol Synthesis of Polymer-Protected Monometallic Nanoparticles Prepared in Batch and Continuous-Flow Processing” Industrial & Engineering Chemistry Research 2016, 55, 5634–5643
J. Zhang , S. Chang, B. H. R. Suryanto, C. Gong, X. Zeng, C. Zhao, Q. Zeng, J. Xie “Efficient Synthesis of Ir-Polyoxometalate Cluster Using a Continuous Flow Apparatus and STM Investigation of Its Coassembly Behavior on HOPG Surface” Inorganic Chemistry 2016, 55, 5585–5591
L. Zane Miller , J. J. Rutowski, J. A. Binns, G. Orts-Gil, D. T. McQuade, J. L. Steinbacher “Flow-Based Surface Decoration of Microparticles with Titania and Other Transition Metal Oxide Nanoparticles” Journal of Flow Chemistry 2016, 6, 94–100
D. S. De , S. A. Marinkovic, E. C. Romani, T. D. Rosso, R. O. M. A. de Souza, A. Massi, O. Pandoli “Prototyping of Meso- and Microfluidic Devices with Embedded TiO2 Photocatalyst for Photodegradation of an Organic Dye” Journal of Flow Chemistry 2016, 6, 101–109
N. Aoki , A. Sato, H. Sasaki, A.-A. Litwinowicz, G. Seong, T. Aida, D. Hojo, S. Takami, T. Adschiri “Kinetics Study to Identify Reaction-Controlled Conditions for Supercritical Hydrothermal Nanoparticle Synthesis with Flow-Type Reactors” The Journal of Supercritical Fluids 2016, 110, 161–166
B. Ikizler , S. M. Peker “Synthesis of Tio2 Coated Zno Nanorod Arrays and Their Stability in Photocatalytic Flow Reactors” Thin Solid Films 2016, 605, 232–242
P. Plouffe , M. Bittel, J. Sieber, D. M. Roberge, A. Macchi “On the Scale-Up of Micro-Reactors for Liquid–Liquid Reactions” Chemical Engineering Science 2016, 143, 216–225