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H. Sprenger
H. Sprenger
Institute of Pathology, Medical University of Graz, Graz, Austria
Institute of Molecular Biosciences, University of Graz, Graz, Austria
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Institute of Molecular Biosciences, University of Graz, Graz, Austria
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Ellen L. Zechner
Ellen L. Zechner
Institute of Molecular Biosciences, University of Graz, Graz, Austria
Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50/I, A-8010, Graz, Austria
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Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50/I, A-8010, Graz, Austria
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Gregor Gorkiewicz
Gregor Gorkiewicz
Institute of Pathology, Medical University of Graz, Graz, Austria
Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A-8036, Graz, Austria
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Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A-8036, Graz, Austria
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Abstract
Campylobacter fetus comprises two subspecies, C. fetus subsp. fetus and C. fetus subsp. venerealis, which are considered emerging pathogens in humans and animals. Comparisons at the genome level have revealed modest subspecies-specific variation; nevertheless, these two subspecies show distinct host and niche preferences. C. fetus subsp. fetus is a commensal and pathogen of domesticated animals that can be transmitted to humans via contaminated food. The clinical features of human infection can be severe, especially in impaired hosts. In contrast, C. fetus subsp. venerealis is a sexually transmitted pathogen essentially restricted to cattle. Infections leading to bovine venereal campylobacteriosis cause substantial economic losses due to abortion and infertility. Recent genome sequencing of the two subspecies has advanced our understanding of C. fetus adaptations through comparative genomics and the identification of subspecies-specific gene regions predicted to be involved in pathogenesis. The most striking difference between the subspecies is the highly subspecies-specific association of a pathogenicity island in the C. fetus subsp. venerealis chromosome. The inserted region encodes a Type 4 secretion system, which contributes to virulence properties of this organism in vitro. This review describes the main differences in epidemiological, phenotypic, and molecular characteristics of the two subspecies and summarizes recent advances towards understanding the molecular mechanisms of C. fetus pathogenesis.
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Dr. Dunay, Ildiko Rita
Magdeburg, Germany
E-mail: ildiko.dunay@med.ovgu.de
Indexing and Abstracting Services:
- PubMed Central
- Scopus
- ESCI
- CABI
- CABELLS Journalytics
| 2023 | |
|---|---|
| Web of Science | |
| Total Cites WoS |
674 |
| Journal Impact Factor | 3.3 |
| Rank by Impact Factor |
Q2 |
| Impact Factor without Journal Self Cites |
3.1 |
| 5 Year Impact Factor |
3.2 |
| Scimago | |
| Scimago H-index |
15 |
| Scimago Journal Rank |
0.601 |
| Scimago Quartile Score | Microbiology (medical) (Q2) Microbiology (Q3) Immunology and Allergy (Q3) Immunology (Q3) |
| Scopus | |
| Scopus Cite Score |
5.0 |
| Scopus CIte Score Rank |
Microbiology (medical) Q2 |
| Scopus SNIP |
0.832 |
| European Journal of Microbiology and Immunology | |
|---|---|
| Publication Model | Gold Open Access Online only |
| Submission Fee | none |
| Article Processing Charge | 600 EUR/article Effective from 1st Feb 2025: 900 EUR/article |
| Regional discounts on country of the funding agency | World Bank Lower-middle-income economies: 50% World Bank Low-income economies: 100% |
| Further Discounts | Editorial Board / Advisory Board members: 50% Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100% |
| Subscription Information | Gold Open Access |
| Purchase per Title | |
| European Journal of Microbiology and Immunology | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
2011 |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Akadémiai Kiadó |
| Founder's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2062-509X (Print) |
| ISSN | 2062-8633 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Jun 2024 | 43 | 0 | 0 |
| Jul 2024 | 80 | 0 | 0 |
| Aug 2024 | 70 | 0 | 0 |
| Sep 2024 | 60 | 0 | 0 |
| Oct 2024 | 160 | 0 | 0 |
| Nov 2024 | 109 | 0 | 0 |
| Dec 2024 | 18 | 0 | 0 |
Author:
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