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  • 1 Medical and Scientific Affairs, 4300 Hacienda Dr., Roche Molecular Diagnostics, Pleasanton, CA, 94566, USA
  • | 2 Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland
  • | 3 Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Steinbacher Hohl 2-26, D-60488, Frankfurt am Main, Germany
  • | 4 Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, CA, 95616, USA
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Abstract

By shortening the time to pathogen identification and allowing for detection of organisms missed by blood culture, new molecular methods may provide clinical benefits for the management of patients with sepsis. While a number of reviews on the diagnosis of sepsis have recently been published we here present up-to-date new developments including multiplex PCR, mass spectrometry and array techniques. We focus on those techniques that are commercially available and for which clinical studies have been performed and published.

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