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A Molnár
A Molnár
Semmelweis University, Hungary
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I Jónásné Sztruhár
I Jónásné Sztruhár
Old Age Home of the Municipality of Budapest, Hungary
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ÁA Csontos
ÁA Csontos
Semmelweis University, Hungary
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Cs Ferencz
Cs Ferencz
Szent Imre University Teaching Hospital, Hungary
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Sz Várbíró
Sz Várbíró
Semmelweis University, Hungary
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B Székács
B Székács
Semmelweis University, Hungary
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Progressive loss of muscle mass and strength is a physiological consequence of aging, and without interventions, it usually deteriorates into sarcopenia. In this study, the hypothesis that combined special nutritional–physiotherapeutical intervention to prevent or reverse this biological deterioration in elderly people was tested. The effects of the regular resistance muscle training (PT, n = 17) alone and the combined exercise + special nutrition therapy containing whey protein and vitamin D (PT + NT, n = 17) were monitored for 3 months in 34 elderly patients (12 men and 22 women; mean age: 66.47 years) randomly distributed into two groups at a long-term care facility. Physical exercise alone did not result in significant improvement in skeletal muscle mass or strength, whereas combined intervention significantly increased the muscle strength (22.51 ± 2.35 vs. 24.54 ± 2.65,
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-
1.
Batsis JA , Mackenzie TA , Barre LK , Lopez-Jimenez F , Bartels SJ : Sarcopenia, sarcopenic obesity and mortality in older adults: results from the National Health and Nutrition Examination Survey III. Eur J. Clin. Nutr. 68, 1001–1007 (2014)
-
2.
Bauer J , Biolo G , Cederholm T , Cesari M , Cruz-Jentoft AJ , Morley JE , Phillips S , Sieber C , Stehle P , Teta D , Visvanathan R , Volpi E , Boirie Y : Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group. J. Am. Med. Dir. Assoc. 14, 542–559 (2013)
-
3.
Bauer JM , Kaiser MJ , Sieber CC : Sarcopenia in nursing home residents. J. Am. Med. Dir. Assoc. 9, 545–551 (2008)
-
4.
Bauer JM , Verlaan S , Bautmans I , Brandt K , Donini LM , Maggio M , McMurdo ME , Mets T , Seal C , Wijers SL , Ceda GP , De Vito G , Donders G , Drey M , Greig C , Holmbäck U , Narici M , McPhee J , Poggiogalle E , Power D , Scafoglieri A , Schultz R , Sieber CC , Cederholm T : Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J. Am. Med. Dir. Assoc. 9, 740–747 (2015)
-
5.
Baumgartner RN , Koehler KM , Gallagher D , Romero L , Heymsfield SB , Ross RR , Garry PJ , Lindeman RD : Epidemiology of sarcopenia among the elderly in New Mexico. Am. J. Epidemiol. 147, 755–763 (1998)
-
6.
Biolo G , Cederholm T , Muscaritoli M : Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia. Clin. Nutr. 33, 737–748 (2014)
-
7.
Boirie Y , Morio B , Caumon E , Cano NJ : Nutrition and protein energy homeostasis in elderly. Mech. Ageing Dev. 136–137, 76–84 (2014)
-
8.
Borsheim E , Bui QU , Tissier S , Kobayashi H , Ferrando AA , Wolfe RR : Effect of amino acid supplementation on muscle mass, strength and physical function in elderly. Clin. Nutr. 27, 189–195 (2008)
-
9.
Bozzetti F : Tailoring the nutritional regimen in the elderly cancer patient. Nutrition 31, 612–614 (2015)
-
10.
Breen L , Phillips SM : Skeletal muscle protein metabolism in the elderly: interventions to counteract the ‘anabolic resistance’ of ageing. Nutr. Metab. 8, 68 (2011)
-
11.
Candow DG , Forbes SC , Little JP , Cornish SM , Pinkoski C , Chilibeck PD : Effect of nutritional interventions and resistance exercise on aging muscle mass and strength. Biogerontology 13, 345–358 (2012)
-
12.
Cederholm T , Bosaeus I , Barazzoni R , Bauer J , Van Gossum A , Klek S , Muscaritoli M , Nyulasi I , Ockenga J , Schneider SM , Muscaritoli M , Nyulasi I , Ockenga J , Schneider SM , de van der Schueren MA , Singer P : Diagnostic criteria for malnutrition – an ESPEN consensus statement. Clin. Nutr. 34, 335–340 (2015)
-
13.
Chale A , Cloutier GJ , Hau C , Phillips EM , Dallal GE , Fielding RA : Efficacy of whey protein supplementation on resistance exercise-induced changes in lean mass, muscle strength, and physical function in mobility-limited older adults. J. Gerontol. A Biol. Sci. Med. Sci. 68, 682–690 (2013)
-
14.
Cruz-Jentoft AJ , Baeyens JP , Bauer JM , Boirie Y , Cederholm T , Landi F , Martin FC , Michel JP , Rolland Y , Schneider SM , Topinková E , Vandewoude M , Zamboni M : Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing 39, 412–423 (2010)
-
15.
Deutz NE , Bauer JM , Barazzoni R , Biolo G , Boirie Y , Bosy-Westphal A , Cederholm T , Cruz-Jentoft A , Krznaric Z , Nair KS , Singer P , Teta D , Tipton K , Calder PC : Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN expert group. Clin. Nutr. 33, 929–936 (2014)
-
16.
Dickinson JM , Volpi E , Rasmussen BB : Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle. Exerc. Sport Sci. Rev. 41, 216–223 (2013)
-
17.
Glover EI , Phillips SM , Oates BR , Tang JE , Tarnopolsky MA , Selby A , Smith K , Rennie MJ : Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion. J. Physiol. 586, 6049–6061 (2008)
-
18.
Hegerova P , Dedkova Z , Sobotka L : Early nutritional support and physiotherapy improved long-term self-sufficiency in acutely ill older patients. Nutrition 31, 166–170 (2015)
-
19.
Holloszy JO : The biology of aging. Mayo Clin. Proc. 75 Suppl. S3–S8, discussion S8–S9 (2000)
-
20.
Hughes VA , Frontera WR , Wood M , Evans WJ , Dallal GE , Roubenoff R , Fiatarone Singh MA : Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health. J. Gerontol. A Biol. Sci. Med. Sci. 56, B209–B217 (2001)
-
21.
Janssen I , Heymsfield SB , Ross R : Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J. Am. Geriatr. Soc. 50, 889–896 (2002)
-
22.
Landi F , Liperoti R , Fusco D , Mastropaolo S , Quattrociocchi D , Proia A , Russo A , Bernabei R , Onder G : Prevalence and risk factors of sarcopenia among nursing home older residents. J. Gerontol. A Biol. Sci. Med. Sci. 67, 48–55 (2012)
-
23.
Lauretani F , Russo CR , Bandinelli S , Bartali B , Cavazzini C , Di Iorio A , Corsi AM , Rantanen T , Guralnik JM , Ferrucci L : Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J. Appl. Physiol. 95, 1851–1860 (2003)
-
24.
Luiking YC , Deutz NE , Memelink RG , Verlaan S , Wolfe RR : Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trial. Nutr. J. 13, 9 (2014)
-
25.
McCracken CM : Muscle mass loss in active adults. Master’s Theses, Department of Kinesiology of the School of Health, Physical Education, and Recreation, Indiana University (2009), https://scholarworks.iu.edu/dspace/bitstream/handle/2022/6669/Thesis_Colleen_McCracken.pdf?sequence=1. Accessed 13 Nov 2015
-
26.
Molnár A , Jónásné IS , Várbíró Sz , Székács B : Effect of physical exercise and medical nutrition in elderlies admitted to a care home. Clin. Nutr. 34 Suppl. 1, S165–S166 (2015)
-
27.
Montero-Fernandez N , Serra-Rexach JA : Role of exercise on sarcopenia in the elderly. Eur. J. Phys. Rehabil. Med. 49, 131–143 (2013)
-
28.
Morley JE , Argiles JM , Evans WJ , Bhasin S , Cella D , Deutz NE , Doehner W , Fearon KC , Ferrucci L , Hellerstein MK , Kalantar-Zadeh K , Lochs H , MacDonald N , Mulligan K , Muscaritoli M , Ponikowski P , Posthauer ME , Rossi Fanelli F , Schambelan M , Schols AM , Schuster MW , Anker SD : Nutritional recommendations for the management of sarcopenia. J. Am. Med. Dir. Assoc. 11, 391–396 (2010)
-
29.
Paddon-Jones D , Rasmussen BB : Dietary protein recommendations and the prevention of sarcopenia. Curr. Opin. Clin. Nutr. Metab. Care 12, 86–90 (2009)
-
30.
Patel HP , Syddall HE , Jameson K , Robinson S , Denison H , Roberts HC , Edwards M , Dennison E , Cooper C , Aihie Sayer A : Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS). Age Ageing 42, 378–384 (2013)
-
31.
Thibault R , Genton L , Pichard C : Body composition: why, when and for who? Clin. Nutr. 31(4), 435–447 (2012)
-
32.
Wiswell RA , Hawkins SA , Jaque SV , Hyslop D , Constantino N , Tarpenning K , Marcell T , Schroeder ET : Relationship between physiological loss, performance decrement, and age in master athletes. J. Gerontol. A Biol. Sci. Med. Sci. 56, M618–M626 (2001)
Editor-in-Chief
László ROSIVALL (Semmelweis University, Budapest, Hungary)
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Anna BERHIDI (Semmelweis University, Budapest, Hungary)
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- Gábor SZÉNÁSI (Semmelweis University, Budapest, Hungary)
- Ákos KOLLER (Semmelweis University, Budapest, Hungary)
- Zsolt RADÁK (University of Physical Education, Budapest, Hungary)
- László LÉNÁRD (University of Pécs, Hungary)
- Zoltán UNGVÁRI (Semmelweis University, Budapest, Hungary)
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- Magdolna DANK (Semmelweis University, Budapest, Hungary)
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- Zoltán GIRICZ (Semmelweis University, Budapest, Hungary and Pharmahungary Group, Szeged, Hungary)
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