US Renal Data System 2016 Annual Data Report: epidemiology of kidney disease in the United States. Am. J. Kidney Dis. 69, A4 (2017)
Abdul-Ghani MA , Norton L , DeFronzo RA : Efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus. Curr. Diab. Rep. 12, 230–238 (2012)
Cherney DZ , Perkins BA , Soleymanlou N , Maione M , Lai V , Lee A , Fagan NM , Woerle HJ , Johansen OE , Broedl UC , von Eynatten M : Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 129, 587–597 (2014)
DeFronzo RA , Norton L , Abdul-Ghani M : Renal, metabolic and cardiovascular considerations of SGLT2 inhibition. Nat. Rev. Nephrol. 13, 11–26 (2017)
Goldring W , Welsh C : The effects on renal activity of the oral administration of phlorizin in man. J. Clin. Invest. 13, 749–752 (1934)
Goormaghtigh N : L’appareil neuromyo-arteriel juxtaglomerulaire du rein; ses reactions en pathologie et ses rapports avec le tube urinifere [The neuro-myo-arterial juxtaglomerular apparatus of the kidney; its responses in pathology and its relations with the uriniferous tubule]. C. R. Soc. Biol. 124, 293–296 (1937)
Gosch C , Halbwirth H , Stich K : Phloridzin: biosynthesis, distribution and physiological relevance in plants. Phytochemistry 71, 838–843 (2010)
Gross JL , de Azevedo MJ , Silveiro SP , Canani LH , Caramori ML , Zelmanovitz T : Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care 28, 164–176 (2005)
Guariguata L , Whiting DR , Hambleton I , Beagley J , Linnenkamp U , Shaw JE : Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res. Clin. Pract. 103, 137–149 (2014)
Hansell P : Evaluation of methods for estimating renal medullary blood flow. Renal Physiol. Biochem. 15, 217–230 (1992)
Harsing L (1981): Concluding remarks on renal blood flow. In: Advances in Physiological Sciences (Kidney and Body Fluids, Vol. 11), ed Takacs L, Pergamon Press, Inc., New York, pp. 255–257
Harsing L (1981): Introduction to renal blood flow. In: Advances in Physiological Sciences (Kidney and Body Fluids, Vol. 11), ed Takacs L, Pergamon Press, Inc., New York, pp. 185–189
Harsing L , Biro J , Fonyo A , Daniel F : Effect of hypertonic solutions on renal blood flow and glomerular filtration rate. Acta Physiol. Acad. Sci. Hung. 12, 341–349 (1957)
Harsing L , Fonyodi S , Kabat M , Kover G : Effect of phlorizin and of mercurial diuretics on renal haemodynamics. Acta Physiol. Hung. 12, 363–371 (1957)
Harsing L , Fonyodi S , Laszlo K , Takacs G : Effect of hypertonic infusions on renal haemodynamics. Acta Physiol. Acad. Sci. Hung. 12, 351–361 (1957)
Harsing L , Pelley K : The determination of renal medullary blood flow based on Rb-86 deposit and distribution. Pflugers Arch. Gesamte Physiol. Menschen Tiere 285, 302–312 (1965)
Harsing L , Posch E , Rosivall L , Szabo G : Renal blood flow as measured with 133Xe wash out and 86Rb uptake techniques and with an electromagnetic flowmeter. Acta Med. Acad. Sci. Hung. 32, 239–244 (1975)
Hummel CS , Lu C , Liu J , Ghezzi C , Hirayama BA , Loo DD , Kepe V , Barrio JR , Wright EM : Structural selectivity of human SGLT inhibitors. Am. J. Physiol. Cell Physiol. 302, C373–C382 (2012)
Kumar D , Robertson S , Burns KD : Evidence of apoptosis in human diabetic kidney. Mol. Cell Biochem. 259, 67–70 (2004)
Maliha G , Townsend RR : SGLT2 inhibitors: their potential reduction in blood pressure. J. Am. Soc. Hypertens. 9, 48–53 (2015)
Mather A , Pollock C : Glucose handling by the kidney. Kidney Int. Suppl. 79(120), S1–S6 (2011)
Mora-Fernandez C , Dominguez-Pimentel V , de Fuentes MM , Gorriz JL , Martinez-Castelao A , Navarro-Gonzalez JF : Diabetic kidney disease: from physiology to therapeutics. J. Physiol. 592, 3997–4012 (2014)
Navar LG , Bell PD , Adams PL (1981): Macula densa feedback regulation of renal hemodynamics and renal autoregulation. In: Advances in Physiological Sciences (Kidney and Body Fluids, Vol. 11), ed Takacs L, Pergamon Press, Inc., New York, pp. 205–215.
Navar LG , Inscho EW , Majid SA , Imig JD , Harrison-Bernard LM , Mitchell KD : Paracrine regulation of the renal microcirculation. Physiol. Rev. 76, 425–536 (1996)
Ogurtsova K , da Rocha Fernandes JD , Huang Y , Linnenkamp U , Guariguata L , Cho NH , Cavan D , Shaw JE , Makaroff LE : IDF Diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res. Clin. Pract. 128, 40–50 (2017)
Rosivall L , Fazekas A , Posch E , Szabo G , Harsing L : Effect of renal vasodilatation on intrarenal blood flow distribution. Acta Physiol. Acad. Sci. Hung. 53, 399–408 (1979)
Rosivall L , Hope A , Clausen G : Incomplete and flow dependent extraction of 86Rb in the rat kidney. Errors in local flow estimation. Pflugers Arch. 390, 216–218 (1981)
Rosivall L , Posch E , Simon G , Laszlo E , Harsing L : Intrarenal distribution of renal blood flow in the rat. Acta Physiol. Acad. Sci. Hung. 53, 389–397 (1979)
Rosivall L , Walter J , Harsing L : Effect on intrarenal circulation of sympathetic vasoconstrictor inhibition. Acta Physiol. Acad. Sci. Hung. 51, 343–351 (1978)
Shlipak M : Diabetic nephropathy: preventing progression. BMJ Clin. Evid. 7, 0606 (2010)
Szabo G , Posch E , Rosivall L , Fazekas A , Harsing L : Renal blood flow during ureteral obstruction measured with 133Xe wash out, 86Rb uptake techniques and with an electromagnetic flowmeter. Pflugers Arch. 367, 33–36 (1976)
Szabo G , Posch E , Rosivall L , Fazekas A , Harsing L : The effect of haemorrhage on renal blood flow and intrarenal flow distribution. Injury 9, 146–150 (1977)
Thurau K (1981): Tubulo-glomerular feedback. In: Advances in Physiological Sciences (Kidney and Body Fluids, Vol. 11), ed Takacs L, Pergamon Press, Inc., New York, pp. 75–82
Thurau K , Schnermann J : Die Natriumkonzentration an den Macula densa-Zellen als regulierender Faktor für das Glomerulumfiltrat (Mikropunktionsversuche) [The sodium concentration in the macula densa cells as a regulating factor for glomerular filtration (micropuncture experiments)]. Klin. Wochenschr. 43, 410–413 (1965)
Tuttle KR , Bakris GL , Bilous RW , Chiang JL , de Boer IH , Goldstein-Fuchs J , Hirsch IB , Kalantar-Zadeh K , Narva AS , Navaneethan SD , Neumiller JJ , Patel UD , Ratner RE , Whaley-Connell AT , Molitch ME : Diabetic kidney disease: a report from an ADA Consensus Conference. Am. J. Kidney Dis. 64, 510–533 (2014)
Vallon V , Gerasimova M , Rose MA , Masuda T , Satriano J , Mayoux E , Koepsell H , Thomson SC , Rieg T : SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am. J. Physiol. Renal Physiol. 306, F194–F204 (2014)
van Bommel EJ , Muskiet MH , Tonneijck L , Kramer MH , Nieuwdorp M , van Raalte DH : SGLT2 inhibition in the diabetic kidney – from mechanisms to clinical outcome. Clin. J. Am. Soc. Nephrol. 12, 700–710 (2017)
Washburn WN : Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2. J. Med. Chem. 52, 1785–1794 (2009)
Wright EM , Loo DD , Hirayama BA : Biology of human sodium glucose transporters. Physiol. Rev. 91, 733–794 (2011)