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  • 1 Montclair State University, USA
  • | 2 Montclair State University, USA
  • | 3 Montclair State University, USA
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Purpose

Consumption of alternative flours, such as sprouted chickpea flour, has shown increased popularity in recent years. Foods rich in antioxidants have been shown to influence brachial artery flow-mediated dilation (FMD), a non-invasive test of a crucial layer of the artery called the endothelium. Partially replacing the semolina flour in pasta with sprouted chickpea flour (SCF) may acutely affect endothelial function post-digestion. We sought to determine if FMD was higher, lower, or the same post-digestion of pasta made with 60% semolina flour and 40% SCF (SCF40) vs. post-digestion of pasta made with 100% semolina flour (SEM100, i.e., control).

Methods

Trolox equivalent antioxidant capacity (TEAC) analysis was performed on the same flour samples. Healthy participants underwent a screening visit and two randomized controlled meal data collection visits (SCF40 and SEM100). At each data collection visit, participants consumed 255 g of pasta with butter. FMD was assessed 2–3 h after pasta consumption.

Results

TEAC results showed that SCF40 (2.031 ± 0.096 mmol trolox/100 g sample) had significantly greater antioxidant capacity than SEM100 (1.736 ± 0.046 mmol trolox/100 g sample; p = 0.02). Twenty-two healthy participants (5 men and 17 women; 26 ± 2 years, 66.6 ± 2.3 kg, BMI = 24 ± 1 kg/m2, SBP = 114 ± 3 mmHg, DBP = 75 ± 2 mmHg, HR = 74 ± 3 BPM) were studied. FMD in the SCF40 condition (10.3% ± 1.2%) was greater than the SEM100 condition (7.9% ± 0.8%, p = 0.02).

Conclusion

These data suggest that partial substitution with sprouted chickpea flour in place of semolina flour in pasta acutely improves post-digestion FMD, which may be beneficial for cardiovascular health (ClinicalTrials.gov Identifier: NCT03801486).

  • 1.

    Brand-Williams W , Cuvelier M-E , Berset C : Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci. Technol. 28, 2530 (1995)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Bruno J , Konas D , Matthews E , Feldman C , Pinsley K , Kerrihard A : Sprouted and non-sprouted chickpea flours: effects on sensory traits in pasta and antioxidant capacity. Polish J. Food Nutr. Sci. 69, 203209 (2019)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Future Market Insights (2018). Chickpea Flour Market: APEJ to Remain Dominant: Global Industry Analysis 2012–2016 & Opportunity Assessment 2017–2026 [Online]. Available at: https://www.futuremarketinsights.com/reports/chickpea-flour-market

    • Search Google Scholar
    • Export Citation
  • 4.

    Goñi I , Valentín-Gamazo C : Chickpea flour ingredient slows glycemic response to pasta in healthy volunteers. Food Chem. 81, 511515 (2003)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5.

    Jensen GS , Wu XL , Patterson KM , Barnes J , Carter SG , Scherwitz L , Beaman R , Endres JR , Schauss AG : In vitro and in vivo antioxidant and anti-inflammatory capacities of an antioxidant-rich fruit and berry juice blend. Results of a pilot and randomized, double-blinded, placebo-controlled, crossover study. J. Agric. Food Chem. 56, 83268333 (2008)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 6.

    Khattak AB , Zeb A , Bibi N , Khalil SA , Khattak MS : Influence of germination techniques on phytic acid and polyphenols content of chickpea (Cicer arietinum L.) sprouts. Food Chem. 104, 10741079 (2007)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Luo S , Lei H , Qin H , Xia Y : Molecular mechanisms of endothelial NO synthase uncoupling. Curr. Pharm. Des. 20, 35483553 (2014)

  • 8.

    Lüscher TF , Tanner FC , Tschudi MR , Noll G : Endothelial dysfunction in coronary artery disease. Annu. Rev. Med. 44, 395418 (1993)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Matthews EL , Brian MS , Ramick MG , Lennon-Edwards S , Edwards DDG , Farquhar WB : High dietary sodium reduces brachial artery flow-mediated dilation in humans with salt-sensitive and salt-resistant blood pressure. J. Appl. Physiol. 118, 15105 (2015)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Monahan KD , Feehan RP , Kunselman AR , Preston AG , Miller DL , Lott MEJ : Dose-dependent increases in flow-mediated dilation following acute cocoa ingestion in healthy older adults. J. Appl. Physiol. 111, 156874 (2011)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 11.

    Padilla J , Harris RA , Fly AD , Rink LD , Wallace JP : The effect of acute exercise on endothelial function following a high-fat meal. Eur. J. Appl. Physiol. 98, 256262 (2006)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12.

    Pietta PG : Flavonoids as antioxidants. J. Nat. Prod. 63, 10351042 (2000)

  • 13.

    Richardson RS , Donato AJ , Uberoi A , Wray DW , Lawrenson L , Nishiyama S , Bailey DM : Exercise-induced brachial artery vasodilation: role of free radicals. Am. J. Physiol. Heart Circ. Physiol. 292, H1516522 (2007)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14.

    Sincer İ , Kurtoğlu E , Çoşkun FY , Aktürk S , Vuruşkan E , Düzen İV , Saraçoğlu E , Aktürk E , Hidayet Ş : Association between serum total antioxidant status and flow-mediated dilation in patients with systemic lupus erythematosus: an observational study. Anatol. J. Cardiol. 15, 913918 (2015)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15.

    Varadharaj S , Kelly OJ , Khayat RN , Kumar PS , Ahmed N , Zweier JL : Role of dietary antioxidants in the preservation of vascular function and the modulation of health and disease. Front. Cardiovasc. Med. 4, 64 (2017)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16.

    Willcox BJ , Curb JD , Rodriguez BL : Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies. Am. J. Cardiol. 101, S75S86 (2008)

    • Crossref
    • Search Google Scholar
    • Export Citation

 

 

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Senior editors

Editor(s)-in-Chief: Rosivall, László

Managing Editor: Berhidi, Anna

Co-editor(s): Koller, Ákos; Lénárd, László; Szénási, Gábor; Radák, Zsolt

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  • Benedek, György (Szeged)
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  • Giricz, Zoltán (Budapest)
  • Hamar, János (Budapest)
  • Hantos, Zoltán (Szeged)
  • Hunyady, László (Budapest)
  • Jancsó, Gábor (Szeged)
  • Karádi, Zoltán (Pécs)
  • Palkovits, Miklós (Budapest)
  • Papp, Gyula (Szeged)
  • Pavlik, Gábor (Budapest)
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  • Szabó, Gyula (Szeged)
  • Szelényi, Zoltán (Pécs)
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2020  
Total Cites 245
WoS
Journal
Impact Factor
2,090
Rank by Physiology 62/81 (Q4)
Impact Factor  
Impact Factor 1,866
without
Journal Self Cites
5 Year 1,703
Impact Factor
Journal  0,51
Citation Indicator  
Rank by Journal  Physiology 67/84 (Q4)
Citation Indicator   
Citable 42
Items
Total 42
Articles
Total 0
Reviews
Scimago 29
H-index
Scimago 0,417
Journal Rank
Scimago Physiology (medical) Q3
Quartile Score  
Scopus 270/1140=1,9
Scite Score  
Scopus Physiology (medical) 71/98 (Q3)
Scite Score Rank  
Scopus 0,528
SNIP  
Days from  172
sumbission  
to acceptance  
Days from  106
acceptance  
to publication  

2019  
Total Cites
WoS
137
Impact Factor 1,410
Impact Factor
without
Journal Self Cites
1,361
5 Year
Impact Factor
1,221
Immediacy
Index
0,294
Citable
Items
34
Total
Articles
33
Total
Reviews
1
Cited
Half-Life
2,1
Citing
Half-Life
9,3
Eigenfactor
Score
0,00028
Article Influence
Score
0,215
% Articles
in
Citable Items
97,06
Normalized
Eigenfactor
0,03445
Average
IF
Percentile
12,963
Scimago
H-index
27
Scimago
Journal Rank
0,267
Scopus
Scite Score
235/157=1,5
Scopus
Scite Score Rank
Physiology (medical) 73/99 (Q3)
Scopus
SNIP
0,38

 

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Physiology International
Language English
Size B5
Year of
Foundation
2006 (1950)
Publication
Programme
2021 Volume 108
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per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
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Address
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ISSN 2498-602X (Print)
ISSN 2677-0164 (Online)

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