Search for other papers by Hiromichi Takeda in
Current site
Google Scholar
PubMed
Search for other papers by Kazuyuki Tabira in
Current site
Google Scholar
PubMed
Search for other papers by Wakana Yamamoto in
Current site
Google Scholar
PubMed
Search for other papers by Koume Matsuoka in
Current site
Google Scholar
PubMed
Search for other papers by Jun Horie in
Current site
Google Scholar
PubMed
Abstract
Purpose
The determinants of aerobic capacity are oxygen delivery by the cardiopulmonary system and oxygen extraction by the skeletal muscles. However, the impact of the oxygen extraction capacity of the skeletal muscle is unclear. This study aimed to examine the associations between aerobic capacity; muscle strength, endurance, mass, and quality; and oxygen extraction capacity.
Methods
Twenty-seven healthy young men (mean age, 20.7 ± 0.8 years; body mass index, 21.6 ± 3.2 kg m−2) were recruited. The following parameters were determined: peak work rate (WR) and oxygen uptake (
Results
Multiple regression analysis with WR/kg peak as the dependent variable resulted in the adoption of SMI (β = −0.41, P = 0.036), muscle echo intensity (β = −0.45, P = 0.012) and ΔMOER (β = 0.73, P < 0.001) as significantly associated factors. Multiple regression analysis with
Conclusion
These findings suggest that muscle oxygen extraction rate is associated with aerobic capacity. MOER is a useful indicator because it is not affected by body mass.
-
1.
Levine BD. V ˙O2 max: what do we know, and what do we still need to know? J Physiol 2008; 586(1): 25–34. https://doi.org/10.1113/jphysiol.2007.147629.
-
2.
Waschki B, Kirsten A, Holz O, Müller KC, Meyer T, Watz H, et al. Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest 2011; 140(2): 331–342. https://doi.org/10.1378/chest.10-2521.
-
3.
Löllgen H, Leyk D. Exercise testing in sports medicine. Deutsches Arzteblatt Int 2018; 115(24): 409–416. https://doi.org/10.3238/arztebl.2018.0409.
-
4.
Guyatt GH, Sullivan MJ, Thompson PJ, Fallen EL, Pugsley SO, Taylor DW, et al. The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J 1985; 132(8): 919–923.
-
5.
Wakasugi T, Morishita S, Kaida K, Ikegame K, Uchiyama Y, Domen K. Muscle oxygen extraction and lung function are related to exercise tolerance after allogeneic hematopoietic stem cell transplantation. Support Care Cancer 2021; 29(10): 6039–6048. https://doi.org/10.1007/s00520-021-06178-w.
-
6.
Bassett DR, Jr., Howley ET. Limiting factors for maximum oxygen uptake and determinants of endurance performance. Med Sci Sports Exerc 2000; 32(1): 70–84. https://doi.org/10.1097/00005768-200001000-00012.
-
7.
Skattebo Ø, Calbet JAL, Rud B, Capelli C, Hallén J. Contribution of oxygen extraction fraction to maximal oxygen uptake in healthy young men. Acta Physiol (Oxf) 2020; 230(2): e13486. https://doi.org/10.1111/apha.13486.
-
8.
Barstow TJ. Understanding near infrared spectroscopy and its application to skeletal muscle research. J Appl Physiol (Bethesda, Md : 1985) 2019; 126(5): 1360–1376. https://doi.org/10.1152/japplphysiol.00166.2018.
-
9.
Tabira K, Horie J, Fujii H, Aida T, Ito K, Fukumoto T, et al. The relationship between skeletal muscle oxygenation and systemic oxygen uptake during exercise in subjects with COPD: a preliminary study. Respir Care 2012; 57(10): 1602–1610. https://doi.org/10.4187/respcare.01602.
-
10.
Morrison BN, George K, Kreiter E, Dixon D, Rebello L, Massarotto RJ, et al. Effects of endurance exercise training on left ventricular structure in healthy adults: a systematic review and meta-analysis. Eur J Prev Cardiol 2023; 30(9): 772–793. https://doi.org/10.1093/eurjpc/zwad023.
-
11.
Fukuta H. Effects of exercise training on cardiac function in heart failure with preserved ejection fraction. Card Fail Rev 2020; 6: e27. https://doi.org/10.15420/cfr.2020.17.
-
12.
Misic MM, Rosengren KS, Woods JA, Evans EM. Muscle quality, aerobic fitness and fat mass predict lower-extremity physical function in community-dwelling older adults. Gerontology 2007; 53(5): 260–266. https://doi.org/10.1159/000101826.
-
13.
Segerström Å B, Holmbäck AM, Elzyri T, Eriksson KF, Ringsberg K, Groop L, et al. Upper body muscle strength and endurance in relation to peak exercise capacity during cycling in healthy sedentary male subjects. J Strength Cond Res 2011; 25(5): 1413–1417. https://doi.org/10.1519/JSC.0b013e3181d68579.
-
14.
Segerström AB, Holmbäck AM, Hansson O, Elgzyri T, Eriksson KF, Ringsberg K, et al. Relation between cycling exercise capacity, fiber-type composition, and lower extremity muscle strength and muscle endurance. J Strength Cond Res 2011; 25(1): 16–22. https://doi.org/10.1519/JSC.0b013e31820238c5.
-
15.
Vaara JP, Kyröläinen H, Niemi J, Ohrankämmen O, Häkkinen A, Kocay S, et al. Associations of maximal strength and muscular endurance test scores with cardiorespiratory fitness and body composition. J Strength Cond Res 2012; 26(8): 2078–2086. https://doi.org/10.1519/JSC.0b013e31823b06ff.
-
16.
Wang DXM, Yao J, Zirek Y, Reijnierse EM, Maier AB. Muscle mass, strength, and physical performance predicting activities of daily living: a meta-analysis. J Cachexia Sarcopenia Muscle 2020; 11(1): 3–25. https://doi.org/10.1002/jcsm.12502.
-
17.
American Thoracic Society, & American College of Chest Physicians. ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 2003; 167(2): 211–277. https://doi.org/10.1164/rccm.167.2.211.
-
18.
Myers J, Walsh D, Buchanan N, Froelicher VF. Can maximal cardiopulmonary capacity be recognized by a plateau in oxygen uptake? Chest 1989; 96(6): 1312–1316. https://doi.org/10.1378/chest.96.6.1312.
-
19.
Williams N. The Borg rating of perceived exertion (RPE) scale. Occup Med 2017; 67(5): 404–405. https://doi.org/10.1093/occmed/kqx063.
-
20.
Ferrari M, Muthalib M, Quaresima V. The use of near-infrared spectroscopy in understanding skeletal muscle physiology: recent developments. Philos Trans A Math Phys Eng Sci 2011; 369(1955): 4577–4590. https://doi.org/10.1098/rsta.2011.0230.
-
21.
Caresio C, Molinari F, Emanuel G, Minetto MA. Muscle echo intensity: reliability and conditioning factors. Clin Physiol Funct Imaging 2015; 35(5): 393–403. https://doi.org/10.1111/cpf.12175.
-
22.
Clarke HH, Shay CT, Mathews DK. Strength decrement index: a new test of muscle fatigue. Arch Phys Med Rehabil 1955; 36(6): 376–378.
-
23.
Powers SK, Lawler J, Dempsey JA, Dodd S, Landry G. Effects of incomplete pulmonary gas exchange on V ˙O2 max. J Appl Physiol (Bethesda, Md : 1985) 1989; 66(6): 2491–2495. https://doi.org/10.1152/jappl.1989.66.6.2491.
-
24.
Miura A, Endo M, Sato H, Sato H, Barstow TJ, Fukuba Y. Relationship between the curvature constant parameter of the power-duration curve and muscle cross-sectional area of the thigh for cycle ergometry in humans. Eur J Appl Physiol 2002; 87(3): 238–244. https://doi.org/10.1007/s00421-002-0623-3.
-
25.
Byrd MT, Switalla JR, Eastman JE, Wallace BJ, Clasey JL, Bergstrom HC. Contributions of body-composition characteristics to critical power and anaerobic work capacity. Int J Sports Physiol Perform 2018; 13(2): 189–193. https://doi.org/10.1123/ijspp.2016-0810.
Editor-in-Chief
László ROSIVALL (Semmelweis University, Budapest, Hungary)
Managing Editor
Anna BERHIDI (Semmelweis University, Budapest, Hungary)
Co-Editors
- Gábor SZÉNÁSI (Semmelweis University, Budapest, Hungary)
- Ákos KOLLER (Semmelweis University, Budapest, Hungary)
- Zsolt RADÁK (University of Physical Education, Budapest, Hungary)
- László LÉNÁRD (University of Pécs, Hungary)
- Zoltán UNGVÁRI (Semmelweis University, Budapest, Hungary)
Assistant Editors
- Gabriella DÖRNYEI (Semmelweis University, Budapest, Hungary)
- Zsuzsanna MIKLÓS (Semmelweis University, Budapest, Hungary)
- György NÁDASY (Semmelweis University, Budapest, Hungary)
Hungarian Editorial Board
- György BENEDEK (University of Szeged, Hungary)
- Zoltán BENYÓ (Semmelweis University, Budapest, Hungary)
- Mihály BOROS (University of Szeged, Hungary)
- László CSERNOCH (University of Debrecen, Hungary)
- Magdolna DANK (Semmelweis University, Budapest, Hungary)
- László DÉTÁRI (Eötvös Loránd University, Budapest, Hungary)
- Zoltán GIRICZ (Semmelweis University, Budapest, Hungary and Pharmahungary Group, Szeged, Hungary)
- Zoltán HANTOS (Semmelweis University, Budapest and University of Szeged, Hungary)
- Zoltán HEROLD (Semmelweis University, Budapest, Hungary)
- László HUNYADI (Semmelweis University, Budapest, Hungary)
- Gábor JANCSÓ (University of Pécs, Hungary)
- Zoltán KARÁDI (University of Pecs, Hungary)
- Miklós PALKOVITS (Semmelweis University, Budapest, Hungary)
- Gyula PAPP (University of Szeged, Hungary)
- Gábor PAVLIK (University of Physical Education, Budapest, Hungary)
- András SPÄT (Semmelweis University, Budapest, Hungary)
- Gyula SZABÓ (University of Szeged, Hungary)
- Zoltán SZELÉNYI (University of Pécs, Hungary)
- Lajos SZOLLÁR (Semmelweis University, Budapest, Hungary)
- József TOLDI (MTA-SZTE Neuroscience Research Group and University of Szeged, Hungary)
- Árpád TÓSAKI (University of Debrecen, Hungary)
International Editorial Board
- Dragan DJURIC (University of Belgrade, Serbia)
- Christopher H. FRY (University of Bristol, UK)
- Stephen E. GREENWALD (Blizard Institute, Barts and Queen Mary University of London, UK)
- Tibor HORTOBÁGYI (University of Groningen, Netherlands)
- George KUNOS (National Institutes of Health, Bethesda, USA)
- Massoud MAHMOUDIAN (Iran University of Medical Sciences, Tehran, Iran)
- Tadaaki MANO (Gifu University of Medical Science, Japan)
- Luis Gabriel NAVAR (Tulane University School of Medicine, New Orleans, USA)
- Hitoo NISHINO (Nagoya City University, Japan)
- Ole H. PETERSEN (Cardiff University, UK)
- Ulrich POHL (German Centre for Cardiovascular Research and Ludwig-Maximilians-University, Planegg, Germany)
- Andrej A. ROMANOVSKY (University of Arizona, USA)
- Anwar Ali SIDDIQUI (Aga Khan University, Karachi, Pakistan)
- Csaba SZABÓ (University of Fribourg, Switzerland)
- Eric VICAUT (Université de Paris, UMRS 942 INSERM, France)
Editorial Correspondence:
Physiology International
Semmelweis University
Faculty of Medicine, Institute of Translational Medicine
Nagyvárad tér 4, H-1089 Budapest, Hungary
Phone/Fax: +36-1-2100-100
E-mail: pi@semmelweis.hu
Indexing and Abstracting Services:
- Biological Abstracts
- BIOSIS Previews
- CAB Abstracts
- CABELLS Journalytics
- EMBASE/Excerpta Medica
- Global Health
- Index Copernicus
- Index Medicus
- Medline
- Referativnyi Zhurnal
- SCOPUS
- WoS - Science Citation Index Expanded
| 2023 | |
|---|---|
| Web of Science | |
| Journal Impact Factor | 2.2 |
| Rank by Impact Factor | Q3 (Physiology) |
| Journal Citation Indicator | 0.58 |
| Scopus | |
| CiteScore | 3.4 |
| CiteScore rank | Q2 (Physical Therapy, Sports Therapy and Rehabilitation) |
| SNIP | 0.508 |
| Scimago | |
| SJR index | 0.407 |
| SJR Q rank | Q2 |
| Physiology International | |
|---|---|
| Publication Model | Hybrid |
| Submission Fee | none |
| Article Processing Charge | 1100 EUR/article |
| Printed Color Illustrations | 40 EUR (or 10 000 HUF) + VAT / piece |
| Regional discounts on country of the funding agency | World Bank Lower-middle-income economies: 50% World Bank Low-income economies: 100% |
| Further Discounts | Editorial Board / Advisory Board members: 50% Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100% |
| Subscription fee 2025 | Online subsscription: 752 EUR / 828 USD Print + online subscription: 880 EUR / 968 USD |
| Subscription Information | Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content. |
| Purchase per Title | Individual articles are sold on the displayed price. |
| Physiology International | |
|---|---|
| Language | English |
| Size | B5 |
| Year of Foundation |
2006 (1950) |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Magyar Tudományos Akadémia |
| Founder's Address |
H-1051 Budapest, Hungary, Széchenyi István tér 9. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2498-602X (Print) |
| ISSN | 2677-0164 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Jun 2024 | 0 | 0 | 0 |
| Jul 2024 | 0 | 0 | 0 |
| Aug 2024 | 0 | 0 | 0 |
| Sep 2024 | 0 | 0 | 0 |
| Oct 2024 | 2970 | 6 | 8 |
| Nov 2024 | 4356 | 4 | 4 |
| Dec 2024 | 111 | 3 | 2 |
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.