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  • 1 Debreceni Egyetem, Orvos- és Egészségtudományi Centrum III. Belgyógyászati Klinika, Reumatológia Tanszék Debrecen Móricz Zs. krt. 22. 4032
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A polyarthritisek okának tisztázása sok esetben nem egyszerű, tekintettel a háttérben felmerülő lehetséges kórképek sokféleségére. A pontos diagnózis alapja a részletes anamnézisfelvétel és fizikális vizsgálat. A betegség kronológiája, az ízületi gyulladás megléte, annak lokalizációja, az extraarticularis tünetek, a betegség lefolyása segíthet a diagnózis felállításában. Noha sok klasszikus reumatológiai laboratóriumi teszt nem specifikus, ezek elvégzése a már specifikus tesztekkel együtt, kiegészítve a radiológiai vizsgálatokkal, segítheti a diagnózis felállítását. A korai arthritisből kialakulhat definitív rheumatoid arthritis vagy más definitív ízületi betegség, a folyamat spontán módon regrediálhat, vagy továbbra is nem differenciált maradhat. Az arthritis diagnózisának és kimenetelének optimális megítéléséhez elsődleges a gyulladásos arthritis tényének megállapítása, majd a lehetséges definitív kórképek kizárása, végül a perzisztáló és/vagy destruktív irreverzíbilis forma kockázatának felmérése. Az optimális kezelési stratégia (lehetőleg 3 hónapon belüli) alapján mielőbb elkezdett korai bázisterápiás kezeléssel megelőzhetjük az ízületi destrukciót, funkcióvesztést, és javíthatjuk a beteg életminőségét.

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