Orvosi Hetilap
Volume/Issue:
Volume 148: Issue 5
Changes in the epidemiology of inflammatory bowel diseases
Authors: László Lakatos 1 and Péter László Lakatos 2
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  • 1 Csolnoky Ferenc Kórház I. Belgyógyászati Osztály Veszprém Kórház u. 1. 8200
  • 2 Semmelweis Egyetem I. Belgyógyászati Klinika Budapest
DOI:
https://doi.org/10.1556/oh.2007.27906
Page Count:
223–228
Publication Date:
01 Feb 2007
Online Publication Date:
30 Jan 2007
Article Category:
Research Article
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A gyulladásos bélbetegségek epidemiológiájában az elmúlt két évtizedben jelentős változást látunk. Az IBD korábban a gazdaságilag, iparilag fejlett nyugati országokra volt jellemző, jelenleg azonban a korábban alacsony incidenciájú területeken is egyre gyakoribb. Különösen igaz ez a colitis ulcerosára, melynek incidenciája megközelíti a nyugati országokét. A Crohn-betegség a fejlődő országokban még ritka, ami amellett szól, hogy a feltételezett környezeti faktor(ok) colitis ulcerosában gyorsabban, vagy másként hatnak. Európában a korábbi észak-dél gradiens eltűnőben van, a nyugat–kelet gradiens is csökken. A környezeti tényezők közül bizonyítottnak tekinthető a dohányzás és az appendectomia ellentétes szerepe colitis ulcerosában valamint Crohn-betegségben, továbbá az oralis fogamzásgátlók mérsékelt elősegítő hatása mindkét kórképben. A táplálkozás, a perinatalis tényezők, a pszichés tényezők, és a nem steroid gyulladásgátlók patogenetikai szerepére vonatkozó adatok ellentmondásosak.

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Cover Orvosi Hetilap
Orvosi Hetilap
Print ISSN:
0030-6002
Online ISSN:
1788-6120
Keywords:
IBD; epidemiológia; patogenezis; környezeti tényezők; IBD; epidemiology; pathogenesis; environmental factors

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