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  • 1 Semmelweis Egyetem, Általános Orvostudományi Kar II. Belgyógyászati Klinika, Magyar Tudományos Akadémia Molekuláris Medicina Kutatócsoport Budapest Szentkirályi u. 46. 1088
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Az elhízás a második leggyakoribb megelőzhető halálok. A szív- és érrendszeri betegségek, a 2-es típusú cukorbetegség, a daganatos betegségek, valamint az idő előtti halálozás kockázatát növeli. A túlsúly és az elhízás a daganatok okozta halálozás 14, illetve 20%-áért felelős férfiakban, illetve nőkben. A szerzők az elhízás, a metabolikus szindróma, illetve a kapcsolódó anyagcsere-eltérések, valamint a vastagbéldaganatok közötti összefüggést tekintik át. Ismertetik a gyulladás, a hyperinsulinaemia, az inzulinszerű növekedési faktor-I és az adipokinek szerepét a vastagbélrák kialakulásában.

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