Az endoszkópos kettős papillotomia már évekkel ezelőtt elfoglalta a sebészi transduodenalis papillaplasztika helyét a papilla betegségeiben és krónikus pancreatitisben. A pseudocysták endoszkópos szájaztatása is helyettesítheti a korábban egyeduralkodó sebészi módszereket még az akut pancreatitis nekrotizáló formáiban kialakuló „walled of necrosis” esetében is, akár fertőzött, akár steril folyadékgyülemről van szó. Krónikus pancreatitisben az endoterápia első beavatkozásként ajánlott a gyakran jobb késői fájdalommentességet eredményező sebészi eljárások előtt. A kőtörés, kőoldás vagy -extrakció és a többszörös pancreasstentek, lehetőleg agresszív ballonos tágítás nélkül, fokozatosan kalibrálják a domináns vezeték szűkületét berepedés, ischaemia és oldalági obstrukció nélkül. A recidívamentes periódus megnyúlik (stent nélkül is) az alkoholfogyasztás és a dohányzás teljes elhagyása esetén. Jól kontrollált, randomizált vizsgálat szükséges a többszörös pancreasstentek klinikai előnyének bizonyítására a sebészi technikákkal szemben.
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