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  • 1 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szeged, Dóm tér 10., 6720
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A várandós anyák primer és rekurrens humán cytomegalovirus- (HCMV-) fertőzéséhez társulhat a magzat fertőzése. A HCMV a congenitalis fertőzések leggyakoribb okozója, amelynek legsúlyosabb következményei a szellemi visszamaradottság, progrediáló halláskárosodás, látászavarok. Az anya primer fertőzését követi leggyakrabban a magzat fertőzése, és a magzat károsodásai rendszerint súlyosak. Növekszik az anyai rekurrens fertőzések után jelentkező, különböző súlyosságú tünetekkel járó congenitalis HCMV-fertőzések száma. Az aktív HCMV-fertőzéssel komplikált terhességek gondozásában döntő szerepet játszik a praenatalis diagnosztika. A congenitalis HCMV-fertőzés potenciálisan súlyos következményei ellenére kevés adat áll rendelkezésünkre a HCMV vertikális terjedésének antivirális gyógyszerrel történő megelőzésére, de a passzív immunizálással biztató eredmények vannak. Vakcina hiányában is elkerülhető a várandós anyák aktív HCMV-fertőzése, ha felhívjuk a figyelmet a fertőzés veszélyeire és ismertetjük a fertőzés megelőzésének lehetőségeit.

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