A klinikai tapasztalat azt mutatja, hogy a jelenleg elérhető kritériumok alapján kiválasztott szívelégtelen betegek közel egyharmada a kardiális reszinkronizációs terápia (CRT) ellenére nonreszpondernek bizonyul, vagyis az optimális kezelés ellenére klinikai állapotukban javulás nem észlelhető. Ez a tény vezetett ahhoz a kutatási irányhoz, hogy találjunk olyan, noninvazív képalkotó diagnosztika (például echokardiográfia) során mérhető és/vagy számítható értéket, amely alkalmas a diszszinkrónia megítélésére és jobban segíti kiválasztani a CRT-re alkalmas betegeket. Ennek az áttekintő közleménynek a célja a legújabb noninvazív echokardiográfiás módszer, a real-time háromdimenziós echokardiográfia lehetséges szerepének bemutatása lenne az elérhető irodalom alapján.
Vardas, P. E., Auricchio, A., Blanc, J. J. és mtsai: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association: Guidelines for cardiac pacing and cardiac resynchronisation therapy. Eur. Heart. J., 2007, 28 , 2256–2295.
Blanc J. J. , 'The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association: Guidelines for cardiac pacing and cardiac resynchronisation therapy ' (2007 ) 28 Eur. Heart. J. : 2256 -2295 .
Chung, E. S., Leon, A. R., Tavazzi, L. és mtsai: Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation, 2008, 117 , 2608–2616.
Tavazzi L. , 'Results of the Predictors of Response to CRT (PROSPECT) trial ' (2008 ) 117 Circulation : 2608 -2616 .
Franke, A., Kuhl, H. P.: Second-generation real-time 3D echocardiography: a revolutionary new technology. MedicaMundi, 2003, 47 , 34–40.
Kuhl H. P. , 'Second-generation real-time 3D echocardiography: a revolutionary new technology ' (2003 ) 47 MedicaMundi : 34 -40 .
Nemes, A., Geleijnse, M. L., Soliman, O. I. és mtsai: Real-time 3-dimensional echocardiography: can there be one more dimension? Orv. Hetil., 2007, 148 , 2451–2460.
Soliman O. I. , 'Real-time 3-dimensional echocardiography: can there be one more dimension? ' (2007 ) 148 Orv. Hetil. : 2451 -2460 .
Krenning, B. J., Szili-Török, T., Voormolen, M. M. és mtsai: Guiding and optimization of resynchronization therapy with dynamic three-dimensional echocardiography and segmental volume-time curves: a feasibility study. Eur. J. Heart. Fail., 2004, 6 , 619–625.
Voormolen M. M. , 'Guiding and optimization of resynchronization therapy with dynamic three-dimensional echocardiography and segmental volume-time curves: a feasibility study ' (2004 ) 6 Eur. J. Heart. Fail. : 619 -625 .
Kapetanakis, S., Kearney, M. T., Siva, A. és mtsai: Real-time three-dimensional echocardiography: a novel technique to quantify global left ventricular mechanical dyssynchrony. Circulation, 2005, 112 , 992–1000.
Siva A. , 'Real-time three-dimensional echocardiography: a novel technique to quantify global left ventricular mechanical dyssynchrony ' (2005 ) 112 Circulation : 992 -1000 .
Zeng, X., Shu, X. H., Pan, C. Z. és mtsai: Assessment of left ventricular systolic synchronicity by real-time three-dimensional echocardiography in patients with dilated cardiomyopathy. Chin. Med. J. (Engl), 2006, 119 , 919–924.
Pan C. Z. , 'Assessment of left ventricular systolic synchronicity by real-time three-dimensional echocardiography in patients with dilated cardiomyopathy ' (2006 ) 119 Chin. Med. J. (Engl) : 919 -924 .
Vieira, M. L., Cury, A. F., Naccarato, G. és mtsai: Analysis of left ventricular regional dyssynchrony: Comparison between real time 3D echocardiography and tissue Doppler imaging. Echocardiography, 2009, 26 , 675–683.
Naccarato G. , 'Analysis of left ventricular regional dyssynchrony: Comparison between real time 3D echocardiography and tissue Doppler imaging ' (2009 ) 26 Echocardiography : 675 -683 .
Takeuchi, M., Jacobs, A., Sugeng, L. és mtsai: Assessment of left ventricular dyssynchrony with real-time 3-dimensional echocardiography: comparison with Doppler tissue imaging. J. Am. Soc. Echocardiogr., 2007, 20 , 1321–1329.
Sugeng L. , 'Assessment of left ventricular dyssynchrony with real-time 3-dimensional echocardiography: comparison with Doppler tissue imaging ' (2007 ) 20 J. Am. Soc. Echocardiogr. : 1321 -1329 .
Marsan, N. A., Henneman, M. M., Chen, J. és mtsai: Real-time three-dimensional echocardiography as a novel approach to quantify left ventricular dyssynchrony: a comparison study with phase analysis of gated myocardial perfusion single photon emission computed tomography. J. Am. Soc. Echocardiogr., 2008, 21 , 801–807.
Chen J. , 'Real-time three-dimensional echocardiography as a novel approach to quantify left ventricular dyssynchrony: a comparison study with phase analysis of gated myocardial perfusion single photon emission computed tomography ' (2008 ) 21 J. Am. Soc. Echocardiogr. : 801 -807 .
Vieira, M. L., Cury, A. F., Gustavo, N. és mtsai: Ventricular dyssynchrony index: comparison with two-dimensional and three-dimensional ejection fraction. Arq. Bras. Cardiol., 2008, 91 , 142–147, 156–162.
Gustavo N. , 'Ventricular dyssynchrony index: comparison with two-dimensional and three-dimensional ejection fraction ' (2008 ) 91 Arq. Bras. Cardiol. : 142 -147 .
Baker, G. H., Hlavacek, A. M., Chessa, K. S. és mtsai: Left ventricular dysfunction is associated with intraventricular dyssynchrony by 3-dimensional echocardiography in children. J. Am. Soc. Echocardiogr., 2008, 21 , 230–233.
Chessa K. S. , 'Left ventricular dysfunction is associated with intraventricular dyssynchrony by 3-dimensional echocardiography in children ' (2008 ) 21 J. Am. Soc. Echocardiogr. : 230 -233 .
Van Dijk, J., Knaapen, P., Russel, I. K. és mtsai: Mechanical dyssynchrony by 3D echo correlates with acute haemodynamic response to biventricular pacing in heart failure patients. Europace, 2008, 10 , 63–68.
Russel I. K. , 'Mechanical dyssynchrony by 3D echo correlates with acute haemodynamic response to biventricular pacing in heart failure patients ' (2008 ) 10 Europace : 63 -68 .
Gimenes, V. M., Vieira, M. L., Andrade, M. M. és mtsai: Standard values for real-time transthoracic three-dimensional echocardiographic dyssynchrony indexes in a normal population. J. Am. Soc. Echocardiogr., 2008, 21 , 1229–1235.
Andrade M. M. , 'Standard values for real-time transthoracic three-dimensional echocardiographic dyssynchrony indexes in a normal population ' (2008 ) 21 J. Am. Soc. Echocardiogr. : 1229 -1235 .
Delgado, V., Sitges, M., Vidal, B. és mtsai: Assessment of left ventricular dyssynchrony by real-time three-dimensional echocardiography. Rev. Esp. Cardiol., 2008, 61 , 825–834.
Vidal B. , 'Assessment of left ventricular dyssynchrony by real-time three-dimensional echocardiography ' (2008 ) 61 Rev. Esp. Cardiol. : 825 -834 .
Marsan, N. A., Bleeker, G. B., Ypenburg, C. és mtsai: Real-time three-dimensional echocardiography as a novel approach to assess left ventricular and left atrium reverse remodeling and to predict response to cardiac resynchronization therapy. Heart. Rhythm., 2008, 5 , 1257–1264.
Ypenburg C. , 'Real-time three-dimensional echocardiography as a novel approach to assess left ventricular and left atrium reverse remodeling and to predict response to cardiac resynchronization therapy ' (2008 ) 5 Heart. Rhythm. : 1257 -1264 .
Soliman, O. I., van Dalen, B. M., Nemes, A. és mtsai: Quantification of left ventricular systolic dyssynchrony by real-time three-dimensional echocardiography. J. Am. Soc. Echocardiogr., 2009, 22 , 232–239.
Nemes A. , 'Quantification of left ventricular systolic dyssynchrony by real-time three-dimensional echocardiography ' (2009 ) 22 J. Am. Soc. Echocardiogr. : 232 -239 .
Conca, C., Faletra, F. F., Miyazaki, C. és mtsai: Echocardiographic parameters of mechanical synchrony in healthy individuals. Am. J. Cardiol., 2009, 103 , 136–142.
Miyazaki C. , 'Echocardiographic parameters of mechanical synchrony in healthy individuals ' (2009 ) 103 Am. J. Cardiol. : 136 -142 .
Marsan, N. A., Bleeker, G. B., Ypenburg, C. és mtsai: Real-time three-dimensional echocardiography permits quantification of left ventricular mechanical dyssynchrony and predicts acute response to cardiac resynchronization therapy. J. Cardiovasc. Electrophysiol., 2008, 19 , 392–399.
Ypenburg C. , 'Real-time three-dimensional echocardiography permits quantification of left ventricular mechanical dyssynchrony and predicts acute response to cardiac resynchronization therapy ' (2008 ) 19 J. Cardiovasc. Electrophysiol. : 392 -399 .
Soliman, O. I., Geleijnse, M. L., Theuns, D. A. és mtsai: Usefulness of left ventricular systolic dyssynchrony by real-time three-dimensional echocardiography to predict long-term response to cardiac resynchronization therapy. Am. J. Cardiol., 2009, 103 , 1586–1591.
Theuns D. A. , 'Usefulness of left ventricular systolic dyssynchrony by real-time three-dimensional echocardiography to predict long-term response to cardiac resynchronization therapy ' (2009 ) 103 Am. J. Cardiol. : 1586 -1591 .