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  • 1 Szegedi Tudományegyetem, Szent-Györgyi Albert Orvos- és Gyógyszerésztudományi Centrum, Általános Orvostudományi Kar Onkoterápiás Klinika Szeged Korányi fasor 12. 6720
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A lokális tumormentesség biztosítása fontos elv az operábilis emlőrák ellátása során. A helyi daganatkiújulás a távoli áttétképződés kockázatát fokozva a beteg életét veszélyezteti. A lokális kontrollt mastectomia és emlőmegtartó műtét után egyaránt javíthatja a posztoperatív sugárterápia, sokszor azonban felesleges, alkalmazása túlkezeléshez vezet. A lokális relapsus kockázata különböző, egymással összefüggést mutató jellemzők alapján becsülhető meg. Ezek a műtét típusa, a tumor mérete, illetve stádiuma, a nyirokcsomóstátus, a sebészi szél, az életkor, a mammográfiás megjelenés és a daganat szövettani és biológiai jellemzői, illetve többgócúsága. A sugárterápia olykor fatális késői szövődményei a besugárzás után 5-10 évvel jelentkezhetnek, igényes technikával megelőzhetők. A szisztémás terápiák jelentősen csökkentik a lokális recidíva kockázatát, és olykor helyettesíthetik a sugárterápiát. Más alacsony rizikójú esetekben a sugárterápia elhagyható vagy az eddiginél kevésbé radikális módszerrel végezhető. A lokális terápia individualizálása javasolt.

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