Napjainkban egyre több klinikai tapasztalat kerül ismertetésre az emlőbimbó-megtartó mastectomiákról. A műtét a tumorosan nem érintett bőr és emlőbimbó-areola komplex megőrzésével nagyban elősegíti az azonnali rekonstrukciót és az esztétikai eredményességet. A beavatkozás azonban komoly onkológiai aggályokat is felvet az emlőbimbóban és retroareolarisan visszamaradó parenchyma esetleges okkult vagy új primer tumoros rizikójával kapcsolatosan. A módszer egyre fokozódó népszerűsége ellenére nem áll rendelkezésre bizonyítékon alapuló igazolás. Az irodalmi adatok alapján az emlőbimbó-megtartó mastectomia onkológiai megbízhatóságáról egyértelmű következtetést nem lehet levonni, így az eljárás jelenleg általánosan nem képezi alternatíváját a standard mastectomiának. A kockázatcsökkentő indikációkban a beavatkozás létjogosultsága megalapozottnak tűnik és várhatóan elősegíti, hogy a nagy kockázatú betegek nagyobb arányban elfogadják a sebészi profilaxist. Az eljárás jól szelektált betegeknél, megfelelő pre- és intraoperatív vizsgálatokkal, precíz technikával a beteg adekvát felvilágosítása mellett, a nemzetközi ajánlásoknak megfelelően, lehetőség szerint klinikai vizsgálatok kereteiben folytatandó. Az érdemi véleményalkotáshoz további hosszú távú eredmények szükségesek. A szerzők közleményükben magyar nyelven elsőként ismertetik részletesen a műtét technikáját és adnak széles körű irodalmi áttekintést. Orv. Hetil., 2011, 152, 1233–1249.
Fisher, B., Jeong, J. H., Anderson, S. és mtsai: Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N. Engl. J. Med., 2002, 347, 567–575.
Anderson S. , 'Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation ' (2002 ) 347 N. Engl. J. Med. : 567 -575 .
Lázár Gy., Besznyák I., Boross G.: Az emlőrák korszerű sebészi kezelése. Magy. Onkol., 2010, 54, 211–216.
Boross G. , 'Az emlőrák korszerű sebészi kezelése ' (2010 ) 54 Magy. Onkol. : 211 -216 .
Cordeiro, P. G.: Breast reconstruction after surgery for breast cancer. N. Engl. J. Med., 2008, 359, 1590–1601.
Cordeiro P. G. , 'Breast reconstruction after surgery for breast cancer ' (2008 ) 359 N. Engl. J. Med. : 1590 -1601 .
Mátrai Z., Gulyás G., Tóth L. és mtsai: A modern emlősebészet onkoplasztikai kihívásai. Magy. Onkol., 2011, 55, 40–52.
Tóth L. , 'A modern emlősebészet onkoplasztikai kihívásai ' (2011 ) 55 Magy. Onkol. : 40 -52 .
Reefy, S., Patani, N., Anderson, A. és mtsai: Oncological outcome and patient satisfaction with skin-sparing mastectomy and immediate breast reconstruction: a prospective observational study. BMC Cancer, 2010, 10, 171.
Anderson A. , 'Oncological outcome and patient satisfaction with skin-sparing mastectomy and immediate breast reconstruction: a prospective observational study ' (2010 ) 10 BMC Cancer : 171 -.
Rusby, J. E., Smith, B. L., Gui, G. P.: Nipple-sparing mastectomy. Br. J. Surg., 2010, 97, 305–316.
Gui G. P. , 'Nipple-sparing mastectomy ' (2010 ) 97 Br. J. Surg. : 305 -316 .
Kronowitz, S. J., Lam, C., Terefe, W. és mtsai: A multidisciplinary protocol for planned skin-preserving delayed breast reconstruction for patients with locally advanced breast cancer requiring postmastectomy radiation therapy: 3-year follow-up. Plast. Reconstr. Surg., 2011, 127, 2154–2166.
Terefe W. , 'A multidisciplinary protocol for planned skin-preserving delayed breast reconstruction for patients with locally advanced breast cancer requiring postmastectomy radiation therapy: 3-year follow-up ' (2011 ) 127 Plast. Reconstr. Surg. : 2154 -2166 .
Garcia-Etienne, C. A., Cody, H. S., Disa, J. J. és mtsai: Nipple-sparing mastectomy: initial experience at the Memorial Sloan-Kettering Cancer Center and a comprehensive review of literature. Breast J., 2009, 15, 440–449.
Disa J. J. , 'Nipple-sparing mastectomy: initial experience at the Memorial Sloan-Kettering Cancer Center and a comprehensive review of literature ' (2009 ) 15 Breast J. : 440 -449 .
Gerber, B., Krause, A., Dieterich, M. és mtsai: The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologus reconstruction: extended follow-up study. Ann. Surg., 2009, 249, 461–468.
Dieterich M. , 'The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologus reconstruction: extended follow-up study ' (2009 ) 249 Ann. Surg. : 461 -468 .
Bleicher, R. J., Hansen, N. M., Giuliano, A. E.: Skin-sparing mastectomy. Specialty bias and worldwide lack of consensus. Cancer, 2003, 98, 2316–2321.
Giuliano A. E. , 'Skin-sparing mastectomy. Specialty bias and worldwide lack of consensus ' (2003 ) 98 Cancer : 2316 -2321 .
Babiera, G., Simmons, R.: Nipple-areolar complex-sparing mastectomy: feasibility, patient selection, and technique. Ann. Surg. Oncol., 2010, 17 (Suppl. 3), 245–248.
Simmons R. , 'Nipple-areolar complex-sparing mastectomy: feasibility, patient selection, and technique ' (2010 ) 17 Ann. Surg. Oncol. : 245 -248 .
Freeman, B. S.: Subcutaneous mastectomy for bening breast lesions with immediate or delayed prosthetic replacement. Plast. Reconstr. Surg., 1962, 30, 676–682.
Freeman B. S. , 'Subcutaneous mastectomy for bening breast lesions with immediate or delayed prosthetic replacement ' (1962 ) 30 Plast. Reconstr. Surg. : 676 -682 .
Toth, B. A., Lappert, P.: Modified skin incisions for mastectomy: the need for plastic surgical input in pre-operative planning. Plast. Reconstr. Surg., 1991, 87, 1048–1053.
Lappert P. , 'Modified skin incisions for mastectomy: the need for plastic surgical input in pre-operative planning ' (1991 ) 87 Plast. Reconstr. Surg. : 1048 -1053 .
Simmons, R. M., Fish, S. K., Gayle, L. és mtsai: Local and distant recurrence rates in skin-sparing mastectomies compared with non-skinsparing mastectomies. Ann. Surg. Oncol., 1999, 6, 676–681.
Gayle L. , 'Local and distant recurrence rates in skin-sparing mastectomies compared with non-skinsparing mastectomies ' (1999 ) 6 Ann. Surg. Oncol. : 676 -681 .
Rivadeneira, D. E., Simmons, R. M., Fish, S. K. és mtsai: Skin-sparing mastectomy with immediate breast reconstruction: a critical analysis of local recurrence. Cancer J., 2000, 6, 331–335.
Fish S. K. , 'Skin-sparing mastectomy with immediate breast reconstruction: a critical analysis of local recurrence ' (2000 ) 6 Cancer J. : 331 -335 .
Kroll, S. S., Khoo, A., Singletary, S. E. és mtsai: Local recurrence risk after skin-sparing and conventional mastectomy: a 6-year follow-up. Plast. Reconstr. Surg., 1999, 104, 421–425.
Singletary S. E. , 'Local recurrence risk after skin-sparing and conventional mastectomy: a 6-year follow-up ' (1999 ) 104 Plast. Reconstr. Surg. : 421 -425 .
Greenway, R. M., Schlossberg, L., Dooley, W. C.: Fifteen-year series of skin-sparing mastectomy for stage 0 to 2 breast cancer. Am. J. Surg., 2005, 190, 918–922.
Dooley W. C. , 'Fifteen-year series of skin-sparing mastectomy for stage 0 to 2 breast cancer ' (2005 ) 190 Am. J. Surg. : 918 -922 .
Carlson, G. W., Bostwick, J., Styblo, T. N. és mtsai: Skin sparing mastectomy, oncologic and reconstructive considerations. Ann. Surg., 1998, 225, 570–578.
Styblo T. N. , 'Skin sparing mastectomy, oncologic and reconstructive considerations ' (1998 ) 225 Ann. Surg. : 570 -578 .
Spear, S., Schwarz, K. A., Venturi, M. L. és mtsai: Prophylactic mastectomy and reconstruction: Clinical outcomes and patient satisfaction. Plast. Reconstr. Surg., 2008, 122, 1–9.
Venturi M. L. , 'Prophylactic mastectomy and reconstruction: Clinical outcomes and patient satisfaction ' (2008 ) 122 Plast. Reconstr. Surg. : 1 -9 .
Nahabedian, M. Y., Tsangaris, T. N.: Breast reconstruction following subcutaneous mastectomy for cancer: a critical appraisal of the nipple-areola complex. Plast. Reconstr. Surg., 2006, 117, 1083–1090.
Tsangaris T. N. , 'Breast reconstruction following subcutaneous mastectomy for cancer: a critical appraisal of the nipple-areola complex ' (2006 ) 117 Plast. Reconstr. Surg. : 1083 -1090 .
Jabor, M. A., Shayani, P., Collins, D. R. és mtsai: Nipple areola reconstruction: satisfaction and clinical determinants. Plast. Reconstr. Surg., 2002, 110, 457–463.
Collins D. R. , 'Nipple areola reconstruction: satisfaction and clinical determinants ' (2002 ) 110 Plast. Reconstr. Surg. : 457 -463 .
Chung, A. P., Sacchini, V.: Nipple-sparing mastectomy: Where are we now? Surg. Oncol., 2008, 17, 261–266.
Sacchini V. , 'Nipple-sparing mastectomy: Where are we now? ' (2008 ) 17 Surg. Oncol. : 261 -266 .
Mátrai Z., Gulyás G., Tóth L. és mtsai: Emlőmegtartásos onkoplasztikai sebészi lehetőségek centrális elhelyezkedésű malignus emlőtumorok kezelésében. Orv. Hetil., 2010, 151, 2105–2112.
Tóth L. , 'Emlőmegtartásos onkoplasztikai sebészi lehetőségek centrális elhelyezkedésű malignus emlőtumorok kezelésében ' (2010 ) 151 Orv. Hetil. : 2105 -2112 .
Smith, J., Payne, W. S., Carney, J. A.: Involvement of the nipple and areola in carcinoma of the breast. Surg. Gynaecol. Obstet., 1976, 143, 56–58.
Carney J. A. , 'Involvement of the nipple and areola in carcinoma of the breast ' (1976 ) 143 Surg. Gynaecol. Obstet. : 56 -58 .
Lagios, M. D., Westdahl, P. R., Rose, M. R. és mtsa: Paget’s disease of the nipple: Alternative management in cases without or with minimal extent of underlying breast carcinoma. Cancer, 1984, 54, 545–551.
Rose M. R. , 'Paget’s disease of the nipple: Alternative management in cases without or with minimal extent of underlying breast carcinoma ' (1984 ) 54 Cancer : 545 -551 .
Cucin, R. L., Guthrie, R. H., Luterman, A. és mtsai: Screening the nipple for involvement in breast cancer. Ann. Plast. Surg., 1980, 5, 477–479.
Luterman A. , 'Screening the nipple for involvement in breast cancer ' (1980 ) 5 Ann. Plast. Surg. : 477 -479 .
Hartmann, L. C., Schaid, D. J., Woods, J. E. és mtsai: Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. N. Engl. J. Med., 1999, 340, 77–84.
Woods J. E. , 'Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer ' (1999 ) 340 N. Engl. J. Med. : 77 -84 .
Gerber, B., Krause, A.: Skin-sparing mastectomy with conservation on the nipple-areola complex and autologous reconstruction is an oncologically safe procedure. Ann. Surg., 2003, 238, 120–127.
Krause A. , 'Skin-sparing mastectomy with conservation on the nipple-areola complex and autologous reconstruction is an oncologically safe procedure ' (2003 ) 238 Ann. Surg. : 120 -127 .
Niemeyer, M., Paepke, S., Schmid, R. és mtsai: Extended indications for nipple-sparing mastectomy. Breast J., 2011, 17, 296–299.
Schmid R. , 'Extended indications for nipple-sparing mastectomy ' (2011 ) 17 Breast J. : 296 -299 .
Nava, M. B., Ottolenghi, J., Pennati, A. és mtsai: Skin/nipple sparing mastectomies and implant-based breast reconstruction in patients with large and ptotic breast: Oncological and reconstructive results.; Breast., 2011 Mar 22. [Epub ahead of print]
Salgarello, M., Visconti, G., Barone-Adesi, L.: Nipple-sparing mastectomy with immediate implant reconstruction: cosmetic outcomes and technical refinements. Plast. Reconstr. Surg., 2010, 126, 1460–1471.
Barone-Adesi L. , 'Nipple-sparing mastectomy with immediate implant reconstruction: cosmetic outcomes and technical refinements ' (2010 ) 126 Plast. Reconstr. Surg. : 1460 -1471 .
Fisher, B., Bauer, M., Margolese, R. és mtsai: Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N. Engl. J. Med., 1985, 312, 665–673.
Margolese R. , 'Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer ' (1985 ) 312 N. Engl. J. Med. : 665 -673 .
Vlajcic, Z., Zic, R., Stanec, S. és mtsai: Nipple-areola complex preservation: predictive factors of neoplastic nipple-areola complex invasion. Ann. Plast. Surg., 2005, 55, 240–244.
Stanec S. , 'Nipple-areola complex preservation: predictive factors of neoplastic nipple-areola complex invasion ' (2005 ) 55 Ann. Plast. Surg. : 240 -244 .
Schecter, A. K., Freeman, M. B., Giri, D. és mtsai: Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients. Ann. Plast. Surg., 2006, 56, 498–504.
Giri D. , 'Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients ' (2006 ) 56 Ann. Plast. Surg. : 498 -504 .
Laronga, C., Kemp, B., Johnston, D. és mtsai: The incidence of occult nipple-areola complex involvement in breast cancer patients receiving a skin-sparing mastectomy. Ann. Surg. Oncol., 1999, 6, 609–613.
Johnston D. , 'The incidence of occult nipple-areola complex involvement in breast cancer patients receiving a skin-sparing mastectomy ' (1999 ) 6 Ann. Surg. Oncol. : 609 -613 .
Loewen, M. J., Jennings, J. A., Sherman, S. R. és mtsai: Mammographic distance as a predictor of nipple-areola complex involvement in breast cancer. Am. J. Surg., 2008, 195, 391–394.
Sherman S. R. , 'Mammographic distance as a predictor of nipple-areola complex involvement in breast cancer ' (2008 ) 195 Am. J. Surg. : 391 -394 .
Rusby, J. E., Brachtel, E. F., Othus, M. és mtsai: Development and validation of a model predictive of occult nipple involvement in women undergoing mastectomy. Br. J. Surg., 2008, 95, 1356–1361.
Othus M. , 'Development and validation of a model predictive of occult nipple involvement in women undergoing mastectomy ' (2008 ) 95 Br. J. Surg. : 1356 -1361 .
Friedman, E. P., Hall-Craggs, M. A., Mumtaz, H. és mtsa: Breast MR and the appearance of the normal and abnormal nipple. Clin. Radiol., 1997, 52, 854–861.
Mumtaz H. , 'Breast MR and the appearance of the normal and abnormal nipple ' (1997 ) 52 Clin. Radiol. : 854 -861 .
Govindarajulu, S., Narreddy, S., Shere, M. H. és mtsai: Preoperative mammotome biopsy of ducts beneath the nipple areola complex. Eur. J. Surg. Oncol., 2006, 32, 410–412.
Shere M. H. , 'Preoperative mammotome biopsy of ducts beneath the nipple areola complex ' (2006 ) 32 Eur. J. Surg. Oncol. : 410 -412 .
National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology, Breast Cancer, Version 2.2011, www.nccn.com
Tang, S. S., Twelves, D. J., Isacke, C. M. és mtsa: Mammary ductoscopy in the current management of breast disease. Surg. Endosc., 2010, 25, 1712–1722.
Isacke C. M. , 'Mammary ductoscopy in the current management of breast disease ' (2010 ) 25 Surg. Endosc. : 1712 -1722 .
Rusby, J. E., Brachtel, E. F., Michaelson, J. S. és mtsai: Breast duct anatomy in the human nipple: three-dimensional patterns and clinical implications. Breast Cancer Res. Treat., 2007, 106, 171–179.
Michaelson J. S. , 'Breast duct anatomy in the human nipple: three-dimensional patterns and clinical implications ' (2007 ) 106 Breast Cancer Res. Treat. : 171 -179 .
Rusby, J. E., Brachtel, E. F., Taghian, A.: Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy. Am. J. Surg., 2007, 194, 433–437.
Taghian A. , 'Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy ' (2007 ) 194 Am. J. Surg. : 433 -437 .
Garwood, E. R., Moore, D., Ewing, C. és mtsai: Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients. Ann. Surg., 2009, 249, 26–32.
Ewing C. , 'Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients ' (2009 ) 249 Ann. Surg. : 26 -32 .
Regolo, L., Ballardini, B., Gallarotti, E. és mtsai: Nipple sparing mastectomy: an innovative skin incision for an alternative approach. Breast, 2008, 17, 8–11.
Gallarotti E. , 'Nipple sparing mastectomy: an innovative skin incision for an alternative approach ' (2008 ) 17 Breast : 8 -11 .
Chen, C. M., Disa, J. J., Sacchini, V. és mtsai: Nipple-sparing mastectomy and immediate tissue expander/implant breast reconstruction. Plast. Reconstr. Surg., 2009, 124, 1772–1780.
Sacchini V. , 'Nipple-sparing mastectomy and immediate tissue expander/implant breast reconstruction ' (2009 ) 124 Plast. Reconstr. Surg. : 1772 -1780 .
Beer, G. M., Varga, Z., Budi, S. és mtsai: Incidence of the superficial fascia and its relevance in skin-sparing mastectomy. Cancer, 2002, 94, 1619–1625.
Budi S. , 'Incidence of the superficial fascia and its relevance in skin-sparing mastectomy ' (2002 ) 94 Cancer : 1619 -1625 .
Wijayanayagam, A., Kumar, A. S., Foster, R. D. és mtsa: Optimizing the total skin-sparing mastectomy. Arch. Surg., 2008, 143, 38–45.
Foster R. D. , 'Optimizing the total skin-sparing mastectomy ' (2008 ) 143 Arch. Surg. : 38 -45 .
Crowe, J. P., Patrick, R. J., Yetman, R. J. és mtsa: Nipple-sparing mastectomy update: one hundred forty-nine procedures and clinical outcomes. Arch. Surg., 2008, 143, 1106–1110.
Yetman R. J. , 'Nipple-sparing mastectomy update: one hundred forty-nine procedures and clinical outcomes ' (2008 ) 143 Arch. Surg. : 1106 -1110 .
Palmieri, B., Baitchev, G., Grappolini, S. és mtsai: Delayed nipple-sparing modified subcutaneous mastectomy: rationale and technique. Breast J., 2005, 11, 173–178.
Grappolini S. , 'Delayed nipple-sparing modified subcutaneous mastectomy: rationale and technique ' (2005 ) 11 Breast J. : 173 -178 .
Petit, J. Y., Veronesi, U., Orecchia, R. és mtsai: Nipple sparing mastectomy with nipple areola intraoperative radiotherapy: one thousand and one cases of a five-year experience at the European institute of oncology of Milan (EIO). Breast Cancer Res. Treat., 2009, 117, 333–338.
Orecchia R. , 'Nipple sparing mastectomy with nipple areola intraoperative radiotherapy: one thousand and one cases of a five-year experience at the European institute of oncology of Milan (EIO) ' (2009 ) 117 Breast Cancer Res. Treat. : 333 -338 .
Rainsbury, R. M.: Skin-sparing mastectomy. Br. J. Surg., 2006, 93, 276–281.
Rainsbury R. M. , 'Skin-sparing mastectomy ' (2006 ) 93 Br. J. Surg. : 276 -281 .
Yamashita, K., Shimizu, K.: Endoscopic video-assisted breast surgery: procedures and short-term results. J. Nippon Med. Sch., 2006, 73, 193–202.
Shimizu K. , 'Endoscopic video-assisted breast surgery: procedures and short-term results ' (2006 ) 73 J. Nippon Med. Sch. : 193 -202 .
Benediktsson, K. P., Perbeck, L.: Survival in breast cancer after nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants: a prospective trial with 13 years median follow-up in 216 patients. Eur. J. Surg. Oncol., 2008, 34, 143–148.
Perbeck L. , 'Survival in breast cancer after nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants: a prospective trial with 13 years median follow-up in 216 patients ' (2008 ) 34 Eur. J. Surg. Oncol. : 143 -148 .
Brachtel, E. F., Rusby, J. E., Michaelson, J. S. és mtsai: Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens. J. Clin. Oncol., 2009, 27, 4948–4954.
Michaelson J. S. , 'Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens ' (2009 ) 27 J. Clin. Oncol. : 4948 -4954 .
Caruso, F., Ferrara, M., Castiglione, G. és mtsai: Nipple sparing subcutaneous mastectomy: sixty-six months follow-up. Eur. J. Surg. Oncol., 2006, 32, 937–940.
Castiglione G. , 'Nipple sparing subcutaneous mastectomy: sixty-six months follow-up ' (2006 ) 32 Eur. J. Surg. Oncol. : 937 -940 .
Sacchini, V., Pinotti, J. A., Barros, A. C. és mtsai: Nipple-sparing mastectomy for breast cancer and risk reduction: oncologic or technical problem? J. Am. Coll. Surg., 2006, 203, 704–714.
Barros A. C. , 'Nipple-sparing mastectomy for breast cancer and risk reduction: oncologic or technical problem? ' (2006 ) 203 J. Am. Coll. Surg. : 704 -714 .
Margulies, A. G., Hochberg, J., Kepple, J. és mtsai: Total skin-sparing mastectomy without preservation of the nipple-areola complex. Am. J. Surg., 2005, 190, 907–912.
Kepple J. , 'Total skin-sparing mastectomy without preservation of the nipple-areola complex ' (2005 ) 190 Am. J. Surg. : 907 -912 .
Komorowski, A. L., Zanini, V., Regolo, L. és mtsai: Necrotic complications after nipple and areola-sparing mastectomy. World. J. Surg., 2006, 30, 1410–1413.
Regolo L. , 'Necrotic complications after nipple and areola-sparing mastectomy ' (2006 ) 30 World. J. Surg. : 1410 -1413 .
Petit, J. Y., Veronesi, U., Orecchia, R. és mtsai: Nipple-sparing mastectomy in association with intra operative radiotherapy (ELIOT): A new type of mastectomy for breast cancer treatment. Breast Cancer Res. Treat., 2006, 96, 47–51.
Orecchia R. , 'Nipple-sparing mastectomy in association with intra operative radiotherapy (ELIOT): A new type of mastectomy for breast cancer treatment ' (2006 ) 96 Breast Cancer Res. Treat. : 47 -51 .
Jensen, J. A., Orringer, J. S., Giuliano, A. E.: Nipple-sparing mastectomy in 99 patients with a mean follow-up of 5 years. Ann. Surg. Oncol., 2011, 18, 1665–1670.
Giuliano A. E. , 'Nipple-sparing mastectomy in 99 patients with a mean follow-up of 5 years ' (2011 ) 18 Ann. Surg. Oncol. : 1665 -1670 .
Harness, J. K., Vetter, T. S., Salibian, A. H.: Areola and nipple-areola-sparing mastectomy for breast cancer treatment and risk reduction: report of an initial experience in a community hospital setting. Ann. Surg. Oncol., 2011, 18, 917–922.
Salibian A. H. , 'Areola and nipple-areola-sparing mastectomy for breast cancer treatment and risk reduction: report of an initial experience in a community hospital setting ' (2011 ) 18 Ann. Surg. Oncol. : 917 -922 .
Bistoni, G., Rulli, A., Izzo, L. és mtsai: Nipple-sparing mastectomy. Preliminary results. J. Exp. Clin. Cancer Res., 2006, 25, 495–497.
Izzo L. , 'Nipple-sparing mastectomy. Preliminary results ' (2006 ) 25 J. Exp. Clin. Cancer Res. : 495 -497 .
Djohan, R., Gage, E., Gatherwright, J. és mtsai: Patient satisfaction following nipple-sparing mastectomy and immediate breast reconstruction: an 8-year outcome study. Plast. Reconstr. Surg., 2010, 25, 818–829.
Gatherwright J. , 'Patient satisfaction following nipple-sparing mastectomy and immediate breast reconstruction: an 8-year outcome study ' (2010 ) 25 Plast. Reconstr. Surg. : 818 -829 .
Salzberg, C. A., Ashikari, A. Y., Koch, R. M. és mtsa: An 8-year experience of direct-to-implant immediate breast reconstruction using human acellular dermal matrix (AlloDerm). Plast. Reconstr. Surg., 2011, 127, 514–524.
Koch R. M. , 'An 8-year experience of direct-to-implant immediate breast reconstruction using human acellular dermal matrix (AlloDerm) ' (2011 ) 127 Plast. Reconstr. Surg. : 514 -524 .
Woerdeman, L. A., Hage, J. J., Hofland, M. M. és mtsa: A prospective assessment of surgical risk factors in 400 cases of skin-sparing mastectomy and immediate breast reconstruction with implants to establish selection criteria. Plast. Reconstr. Surg., 2007, 119, 455–463.
Hofland M. M. , 'A prospective assessment of surgical risk factors in 400 cases of skin-sparing mastectomy and immediate breast reconstruction with implants to establish selection criteria ' (2007 ) 119 Plast. Reconstr. Surg. : 455 -463 .
Mosahebi, A., Ramakrishnan, V., Gittos, M. és mtsa: Aesthetic outcome of different techniques of reconstruction following nipple-areola-preserving envelope mastectomy with immediate reconstruction. Plast. Reconstr. Surg., 2007, 119, 796–803.
Gittos M. , 'Aesthetic outcome of different techniques of reconstruction following nipple-areola-preserving envelope mastectomy with immediate reconstruction ' (2007 ) 119 Plast. Reconstr. Surg. : 796 -803 .
Disa, J., Cordeiro, P., Hidalgo, D.: Efficacy of conventional monitoring techniques in free tissue transfer: an 11-year experience in 750 consecutive cases. Plast. Reconstr. Surg., 1999, 104, 97–101.
Hidalgo D. , 'Efficacy of conventional monitoring techniques in free tissue transfer: an 11-year experience in 750 consecutive cases ' (1999 ) 104 Plast. Reconstr. Surg. : 97 -101 .
Leone, M. S., Priano, V., Franchelli, S. és mtsai: Factors affecting symmetrization of the contralateral breast: A 7-year unilateral postmastectomy breast reconstruction experience.; Aesthetic. Plast. Surg., 2010 Dec 7. [Epub ahead of print]
Stolier, A., Wang, J.: Terminal Duct lobular units are scarce in the nipple: implications for prophylatic nipple-sparing mastectomy. Ann. Surg. Oncol., 2007, 15, 438–442.
Wang J. , 'Terminal Duct lobular units are scarce in the nipple: implications for prophylatic nipple-sparing mastectomy ' (2007 ) 15 Ann. Surg. Oncol. : 438 -442 .
Pennisi, V. R., Capozzi, A.: Subcutaneous mastectomy data: a final statistical analysis of 1500 patients. Aesthetic. Plast. Surg., 1989, 13, 15–21.
Capozzi A. , 'Subcutaneous mastectomy data: a final statistical analysis of 1500 patients ' (1989 ) 13 Aesthetic. Plast. Surg. : 15 -21 .
McDonnell, S. K., Schaid, D. J., Myers, J. L. és mtsai: Efficacy of contralateral prophylactic mastectomy in women with a personal and family history of breast cancer. J. Clin. Oncol., 2001, 19, 3938–3943.
Myers J. L. , 'Efficacy of contralateral prophylactic mastectomy in women with a personal and family history of breast cancer ' (2001 ) 19 J. Clin. Oncol. : 3938 -3943 .
Rebbeck, T. R., Friebel, T., Lynch, H. T. és mtsai: Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: The PROSE study group. J. Clin. Oncol., 2004, 22, 1055–1062.
Lynch H. T. , 'Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: The PROSE study group ' (2004 ) 22 J. Clin. Oncol. : 1055 -1062 .
Metcalfe, K. A., Semple, J. L., Narod, S. A.: Time to reconsider subcutaneous mastectomy for breast-cancer prevention? Lancet Oncol., 2005, 6, 431–434.
Narod S. A. , 'Time to reconsider subcutaneous mastectomy for breast-cancer prevention? ' (2005 ) 6 Lancet Oncol. : 431 -434 .
Barton, F. E. Jr., English, J. M., Kingsley, W. B. és mtsa: Glandular excision in total glandular mastectomy and modified radical mastectomy: a comparison. Plast. Reconstr. Surg., 1991, 88, 389–392.
Kingsley W. B. , 'Glandular excision in total glandular mastectomy and modified radical mastectomy: a comparison ' (1991 ) 88 Plast. Reconstr. Surg. : 389 -392 .
Carlson, G. W., Grossl, N., Lewis, M. M. és mtsai: Preservation of the inframammary fold: what are we leaving behind? Plast. Reconstr. Surg., 1996, 98, 447–450.
Lewis M. M. , 'Preservation of the inframammary fold: what are we leaving behind? ' (1996 ) 98 Plast. Reconstr. Surg. : 447 -450 .
Voltura, A. M., Tsangaris, T. N., Rosson, G. D.: Nipple-sparing mastectomy: critical assessment of 51 procedures and implications for selection criteria. Ann. Surg. Oncol., 2008, 15, 3396–3401.
Rosson G. D. , 'Nipple-sparing mastectomy: critical assessment of 51 procedures and implications for selection criteria ' (2008 ) 15 Ann. Surg. Oncol. : 3396 -3401 .
Horiguchi, J., Iino, J. H. Y., Takei, H. és mtsai: A comparative study of subcutaneous mastectomy with radical mastectomy. Anticancer Res., 2001, 21, 2963–2967.
Takei H. , 'A comparative study of subcutaneous mastectomy with radical mastectomy ' (2001 ) 21 Anticancer Res. : 2963 -2967 .
Allweis, T. M., Boisvert, M. E., Otero, S. E. és mtsai: Immediate reconstruction after mastectomy for breast cancer does not prolong the time to starting adjuvant chemotherapy. Am. J. Surg., 2002, 183, 218–221.
Otero S. E. , 'Immediate reconstruction after mastectomy for breast cancer does not prolong the time to starting adjuvant chemotherapy ' (2002 ) 183 Am. J. Surg. : 218 -221 .
Downes, K. J., Glatt, B. S., Kanchwala, S. K. és mtsai: Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma. Cancer, 2005, 103, 906–913.
Kanchwala S. K. , 'Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma ' (2005 ) 103 Cancer : 906 -913 .
Langstein, H. N., Cheng, M. H., Singletary, S. E. és mtsai: Breast cancer recurrence after immediate reconstruction: patterns and significances. Plast. Reconstr. Surg., 2003, 111, 712–720.
Singletary S. E. , 'Breast cancer recurrence after immediate reconstruction: patterns and significances ' (2003 ) 111 Plast. Reconstr. Surg. : 712 -720 .
Didier, F., Radice, D., Gandini, S. és mtsai: Does nipple preservation in mastectomy improve satisfaction with cosmetic results, psychological adjustment, body image and sexuality? Breast Cancer Res. Treat., 2008, 118, 623–633.
Gandini S. , 'Does nipple preservation in mastectomy improve satisfaction with cosmetic results, psychological adjustment, body image and sexuality? ' (2008 ) 118 Breast Cancer Res. Treat. : 623 -633 .
Denewer, A., Farouk, O.: Can nipple-sparing mastectomy and immediate breast reconstruction with modified extended latissimus dorsi muscular flap improve the cosmetic and functional outcome among patients with breast carcinoma? World J. Surg., 2007, 31, 1169–1177.
Farouk O. , 'Can nipple-sparing mastectomy and immediate breast reconstruction with modified extended latissimus dorsi muscular flap improve the cosmetic and functional outcome among patients with breast carcinoma? ' (2007 ) 31 World J. Surg. : 1169 -1177 .
Sarhadi, N. S., Shaw-Dunn, J., Lee, F. D. és mtsa: An anatomical study of the nerve supply of the breast, including the nipple and areola. Br. J. Plast. Surg., 1996, 49, 156–164.
Lee F. D. , 'An anatomical study of the nerve supply of the breast, including the nipple and areola ' (1996 ) 49 Br. J. Plast. Surg. : 156 -164 .
Laronga, C.: Quality of life with skin-sparing mastectomy: sensation in the nipple-areola complex. J. Support Oncol., 2006, 4, 234–235.
Laronga C. , 'Quality of life with skin-sparing mastectomy: sensation in the nipple-areola complex ' (2006 ) 4 J. Support Oncol. : 234 -235 .