Az érrendszerben létrejövő funkcionális eltérések gyakran megelőzik a morfológiaiakat, így azok diagnosztizálása elméletileg javíthatja az érkárosodás korai felismerését. Az összefoglaló közlemény célja a jelenleg elérhető és a klinikumban már használható noninvazív módszerek bemutatása (vascularis érmerevségi vizsgálatok, coronariaáramlási rezerv vizsgálat, áramlás mediálta vasodilatatiós vizsgálat, myocardialis áramlási rezerv vizsgálat). Orv. Hetil., 2012, 153, 1887–1895.
Nemes, A., Geleijnse, M. L., Forster, T., et al.: Echocardiographic evaluation and clinical implications of aortic stiffness and coronary flow reserve and their relation. Clin. Cardiol., 2008, 31, 304–309.
Forster T. , 'Echocardiographic evaluation and clinical implications of aortic stiffness and coronary flow reserve and their relation ' (2008 ) 31 Clin. Cardiol. : 304 -309 .
Nemes, A., Forster, T.: Evaluation of aortic stiffness by non-invasive methods. [Az aorta stiffness vizsgálata noninvazív módszerekkel.] Metabolizmus, 2009, 7, 101–105. [Hungarian]
Forster T. , 'Evaluation of aortic stiffness by non-invasive methods. [Az aorta stiffness vizsgálata noninvazív módszerekkel.] ' (2009 ) 7 Metabolizmus : 101 -105 .
Belz, G. G.: Elastic properties and Windkessel function of the human aorta. Cardiovasc. Drugs Ther., 1995, 9, 73–83.
Belz G. G. , 'Elastic properties and Windkessel function of the human aorta ' (1995 ) 9 Cardiovasc. Drugs Ther. : 73 -83 .
Pearson, A. C., Guo, R., Orsinelli, D. A., et al.: Transesophageal echocardiographic assessment of the effects of age, gender, and hypertension on thoracic aortic wall size, thickness, and stiffness. Am. Heart J., 1994, 128, 344–351.
Orsinelli D. A. , 'Transesophageal echocardiographic assessment of the effects of age, gender, and hypertension on thoracic aortic wall size, thickness, and stiffness ' (1994 ) 128 Am. Heart J. : 344 -351 .
Peterson, L. N., Jensen, R. E., Parnell, R.: Mechanical properties of arteries in vivo. Circ. Res., 1960, 8, 622–639.
Parnell R. , 'Mechanical properties of arteries in vivo ' (1960 ) 8 Circ. Res. : 622 -639 .
Nichols, W. W., O’Rourke, M. F.: Properties of the arterial wall. In: McDonald’s blood flow in arteries, vol. 77. Lea&Ferbiger, Philadelphia, 1988, 947–954.
O’Rourke M. F. , '', in McDonald’s blood flow in arteries, vol. 77 , (1988 ) -.
Baulmann, J., Schillings, U., Rickert, S., et al.: A new oscillometric method for assessment of arterial stiffness: comparison with tonometric and piezo-electronic methods. J. Hypertens., 2008, 26, 523–528.
Rickert S. , 'A new oscillometric method for assessment of arterial stiffness: comparison with tonometric and piezo-electronic methods ' (2008 ) 26 J. Hypertens. : 523 -528 .
Kröner, E. S., van der Geest, R. J., Scholte, A. J., et al.: Evaluation of sampling density on the accuracy of aortic pulse wave velocity from velocity-encoded MRI in patients with Marfan syndrome. J. Magn. Reson. Imaging, 2012 Jun 22. [Epub ahead of print]
Mancia, G., De Backer, G., Dominiczak, A., et al.: 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J. Hypertens., 2007, 25, 1105–1187.
Dominiczak A. , '2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) ' (2007 ) 25 J. Hypertens. : 1105 -1187 .
Davies, J. I., Struthers, A. D.: Beyond blood pressure: pulse wave analysis – a better way of assessing cardiovascular risk? Future Cardiol., 2005, 1, 69–78.
Struthers A. D. , 'Beyond blood pressure: pulse wave analysis – a better way of assessing cardiovascular risk? ' (2005 ) 1 Future Cardiol. : 69 -78 .
Szeto, C. C., Kwan, B. C., Chow, K. M., et al.: Prognostic value of arterial pulse wave velocity in peritoneal dialysis patients. Am. J. Nephrol., 2012, 35, 127–133.
Chow K. M. , 'Prognostic value of arterial pulse wave velocity in peritoneal dialysis patients ' (2012 ) 35 Am. J. Nephrol. : 127 -133 .
Fazio, G. P., Redberg, R. F., Winslow, T., et al.: Transesophageal echocardiographically detected atherosclerotic aortic plaque is a marker for coronary artery disease. J. Am. Coll. Cardiol., 1993, 21, 144–150.
Winslow T. , 'Transesophageal echocardiographically detected atherosclerotic aortic plaque is a marker for coronary artery disease ' (1993 ) 21 J. Am. Coll. Cardiol. : 144 -150 .
Stefanadis, C., Stratos, C., Boudoulas, H., et al.: Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease. Eur. Heart J., 1990, 11, 990–996.
Boudoulas H. , 'Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease ' (1990 ) 11 Eur. Heart J. : 990 -996 .
Henry, W. L., DeMaria, A., Gramiak, R., et al.: Report of the American Society of Echocardiography Committee on Nomenclature and Standards in Two-dimensional Echocardiography. Circulation, 1980, 62, 212–217.
Gramiak R. , 'Report of the American Society of Echocardiography Committee on Nomenclature and Standards in Two-dimensional Echocardiography ' (1980 ) 62 Circulation : 212 -217 .
Ahmadi, N., Nabavi, V., Hajsadeghi, F., et al.: Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease. Int. J. Cardiovasc. Imaging, 2011, 27, 459–469.
Hajsadeghi F. , 'Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease ' (2011 ) 27 Int. J. Cardiovasc. Imaging : 459 -469 .
Mark, P. B., Doyle, A., Blyth, K. G., et al.: Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease. J. Cardiovasc. Magn. Reson., 2008, 10, 39.
Blyth K. G. , 'Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease ' (2008 ) 10 J. Cardiovasc. Magn. Reson. : 39 -.
Nemes, A., Geleijnse, M. L., Soliman, O. I., et al.: Real-time three-dimensional echocardiography for regional evaluation of aortic stiffness. Eur. J. Echocardiogr., 2007, 8, 161–162.
Soliman O. I. , 'Real-time three-dimensional echocardiography for regional evaluation of aortic stiffness ' (2007 ) 8 Eur. J. Echocardiogr. : 161 -162 .
Harada, K., Yasuoka, K., Shimada, Y.: Usefulness of tissue doppler imaging for assessing aortic wall stiffness in children with the Marfan syndrome. Am. J. Cardiol., 2004, 93, 1072–1075.
Shimada Y. , 'Usefulness of tissue doppler imaging for assessing aortic wall stiffness in children with the Marfan syndrome ' (2004 ) 93 Am. J. Cardiol. : 1072 -1075 .
Petrini, J., Yousry, M., Rickenlund, A., et al.: The feasibility of velocity vector imaging by transesophageal echocardiography for assessment of elastic properties of the descending aorta in aortic valve disease. J. Am. Soc. Echocardiogr., 2010, 23, 985–992.
Rickenlund A. , 'The feasibility of velocity vector imaging by transesophageal echocardiography for assessment of elastic properties of the descending aorta in aortic valve disease ' (2010 ) 23 J. Am. Soc. Echocardiogr. : 985 -992 .
Hwang, J. W., Kang, S. J., Lim, H. S., et al.: Impact of arterial stiffness on regional myocardial function assessed by speckle tracking echocardiography in patients with hypertension. J. Cardiovasc. Ultrasound, 2012, 20, 90–96.
Lim H. S. , 'Impact of arterial stiffness on regional myocardial function assessed by speckle tracking echocardiography in patients with hypertension ' (2012 ) 20 J. Cardiovasc. Ultrasound : 90 -96 .
Flu, W. J., van Kuijk, J. P., Hoeks, S. E., et al.: Intima media thickness of the common carotid artery in vascular surgery patients: a predictor of postoperative cardiovascular events. Am. Heart J., 2009, 158, 202–208.
Hoeks S. E. , 'Intima media thickness of the common carotid artery in vascular surgery patients: a predictor of postoperative cardiovascular events ' (2009 ) 158 Am. Heart J. : 202 -208 .
Akasaka, K., Takai, R., Saito, E., et al.: Investigation of atherosclerosis using carotid ultrasonography. Rinsho Byori, 2010, 58, 809–815.
Saito E. , 'Investigation of atherosclerosis using carotid ultrasonography ' (2010 ) 58 Rinsho Byori : 809 -815 .
Kelm, M.: Flow-mediated dilatation in human circulation: diagnostic and therapeutic aspects. Am. J. Physiol. Heart Circ. Physiol., 2002, 282, H1–H5.
Kelm M. , 'Flow-mediated dilatation in human circulation: diagnostic and therapeutic aspects ' (2002 ) 282 Am. J. Physiol. Heart Circ. Physiol. : H1 -H5 .
Moens, A. L., Goovaerts, I., Claeys, M. J., et al.: Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool? Chest, 2005, 127, 2254–2263.
Claeys M. J. , 'Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool? ' (2005 ) 127 Chest : 2254 -2263 .
Schächinger, V., Britten, M. B., Zeiher, A. M.: Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation, 2000, 101, 1899–1906.
Zeiher A. M. , 'Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease ' (2000 ) 101 Circulation : 1899 -1906 .
Anderson, T. J., Uehata, A., Gerhard, M. D., et al.: Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. Coll. Cardiol., 1995, 26, 1235–1241.
Gerhard M. D. , 'Close relation of endothelial function in the human coronary and peripheral circulations ' (1995 ) 26 J. Am. Coll. Cardiol. : 1235 -1241 .
Laurent, S., Lacolley, P., Brunel, P., et al.: Flow-dependent vasodilation of brachial artery in essential hypertension. Am. J. Physiol., 1990, 258, H1004–H1011.
Brunel P. , 'Flow-dependent vasodilation of brachial artery in essential hypertension ' (1990 ) 258 Am. J. Physiol. : H1004 -H1011 .
Esteban, E., García-Fernández, M. A., González Torrecilla, E., et al.: Transesophageal echocardiography in the assessment of coronary artery anatomy and blood flow. Rev. Esp. Cardiol., 1993, 46, 20–27.
González Torrecilla E. , 'Transesophageal echocardiography in the assessment of coronary artery anatomy and blood flow ' (1993 ) 46 Rev. Esp. Cardiol. : 20 -27 .
Krzanowski, M., Bodzoń, W., Dimitrow, P. P.: Imaging of all three coronary arteries by transthoracic echocardiography. An illustrated guide. Cardiovasc. Ultrasound, 2003, 1, 16.
Dimitrow P. P. , 'Imaging of all three coronary arteries by transthoracic echocardiography. An illustrated guide ' (2003 ) 1 Cardiovasc. Ultrasound : 16 -.
Iliceto, S., Marangelli, V., Memmola, C., et al.: Transesophageal Doppler echocardiography evaluation of coronary blood flow velocity in baseline conditions and during dipyridamole-induced coronary vasodilation. Circulation, 1991, 83, 61–69.
Memmola C. , 'Transesophageal Doppler echocardiography evaluation of coronary blood flow velocity in baseline conditions and during dipyridamole-induced coronary vasodilation ' (1991 ) 83 Circulation : 61 -69 .
Forster, T., Csanády, M.: Stress echocardiography. [Terheléses echokardiográfia.] Medicina Könyvkiadó, Budapest, 1998. [Hungarian]
Csanády M. , '', in Stress echocardiography. [Terheléses echokardiográfia.] , (1998 ) -.
Rigo, F., Cortigiani, L., Pasanisi, E., et al.: The additional prognostic value of coronary flow reserve on left anterior descending artery in patients with negative stress echo by wall motion criteria. A Transthoracic Vasodilator Stress Echocardiography Study. Am. Heart J., 2006, 151, 124–130.
Pasanisi E. , 'The additional prognostic value of coronary flow reserve on left anterior descending artery in patients with negative stress echo by wall motion criteria. A Transthoracic Vasodilator Stress Echocardiography Study ' (2006 ) 151 Am. Heart J. : 124 -130 .
Nemes, A., Forster, T., Geleijnse, M. L., et al.: Prognostic role of atherosclerosis and coronary flow reserve in patients with suspected coronary artery disease. Int. J. Cardiol., 2008, 131, 45–50.
Geleijnse M. L. , 'Prognostic role of atherosclerosis and coronary flow reserve in patients with suspected coronary artery disease ' (2008 ) 131 Int. J. Cardiol. : 45 -50 .
Nemes, A., Forster, T., Geleijnse, M. L., et al.: Prognostic value of coronary flow reserve and aortic distensibility indices in patients with suspected coronary artery disease. Heart Vessels, 2008, 23, 167–173.
Geleijnse M. L. , 'Prognostic value of coronary flow reserve and aortic distensibility indices in patients with suspected coronary artery disease ' (2008 ) 23 Heart Vessels : 167 -173 .
Hutchison, S. J., Soldo, S. J., Gadallah, S., et al.: Determination of coronary flow measurements by transesophageal echocardiography: Dependence of flow velocity reserve on the location of stenosis. Am. Heart J., 1997, 133, 44–52.
Gadallah S. , 'Determination of coronary flow measurements by transesophageal echocardiography: Dependence of flow velocity reserve on the location of stenosis ' (1997 ) 133 Am. Heart J. : 44 -52 .
Stoddard, M. F., Prince, C. R., Morris, G. T.: Coronary flow reserve assessment by dobutamine transesophageal Doppler echocardiography. J. Am. Coll. Cardiol., 1995, 25, 325–332.
Morris G. T. , 'Coronary flow reserve assessment by dobutamine transesophageal Doppler echocardiography ' (1995 ) 25 J. Am. Coll. Cardiol. : 325 -332 .
Nemes, A., Forster, T., Pálinkás, A., et al.: The clinical value of coronary flow reserve in ischemic heart disease as measured by dipyridamole stress transesophageal echocardiography. [A dipiridamolterheléses transoesophagealis echokardiográfia segítségével számított coronariaáramlási rezerv klinikai értéke ischaemiás szívbetegségben.] Orv. Hetil., 2000, 141, 2327–2331. [Hungarian]
Pálinkás A. , 'The clinical value of coronary flow reserve in ischemic heart disease as measured by dipyridamole stress transesophageal echocardiography. [A dipiridamolterheléses transoesophagealis echokardiográfia segítségével számított coronariaáramlási rezerv klinikai értéke ischaemiás szívbetegségben.] ' (2000 ) 141 Orv. Hetil. : 2327 -2331 .
Nemes, A., Forster, T., Varga, A., et al.: How can coronary flow reserve be altered by severe aortic stenosis? Echocardiography, 2002, 19, 655–659.
Varga A. , 'How can coronary flow reserve be altered by severe aortic stenosis? ' (2002 ) 19 Echocardiography : 655 -659 .
Hildick-Smith, D. J., Johnson, P. J., Wisbey, C. R., et al.: Coronary flow reserve is supranormal in endurance athletes: an adenosine transthoracic echocardiographic study. Heart, 2000, 84, 383–389.
Wisbey C. R. , 'Coronary flow reserve is supranormal in endurance athletes: an adenosine transthoracic echocardiographic study ' (2000 ) 84 Heart : 383 -389 .
Nemes, A., Lengyel, C., Forster, T., et al.: Coronary flow reserve, insulin resistance and blood ressure response to standing in patients with normoglycaemia: is there a relationship? Diabet. Med., 2005, 22, 1614–1618.
Forster T. , 'Coronary flow reserve, insulin resistance and blood ressure response to standing in patients with normoglycaemia: is there a relationship? ' (2005 ) 22 Diabet. Med. : 1614 -1618 .
Nemes, A., Forster, T., Csanády, M.: Reduction of coronary flow reserve in patients with increased aortic stiffness. Can. J. Physiol. Pharmacol., 2007, 85, 818–822.
Csanády M. , 'Reduction of coronary flow reserve in patients with increased aortic stiffness ' (2007 ) 85 Can. J. Physiol. Pharmacol. : 818 -822 .
Nemes, A., Balázs, E., Forster, T.: Prognostic value of echocardiography-derived coronary flow reserve. Circ. J., 2012, 76, 2285.
Forster T. , 'Prognostic value of echocardiography-derived coronary flow reserve ' (2012 ) 76 Circ. J. : 2285 -.
Soliman, O. I., Knaapen, P., Geleijnse, M. L., et al.: Assessment of intravascular and extravascular mechanisms of myocardial perfusion abnormalities in obstructive hypertrophic cardiomyopathy by myocardial contrast echocardiography. Heart, 2007, 93, 1204–1212.
Geleijnse M. L. , 'Assessment of intravascular and extravascular mechanisms of myocardial perfusion abnormalities in obstructive hypertrophic cardiomyopathy by myocardial contrast echocardiography ' (2007 ) 93 Heart : 1204 -1212 .
Waggoner, A. D., Ehler, D., Adams, D., et al.: Guidelines for the cardiac sonographer in the performance of contrast echocardiography: recommendations of the American Society of Echocardiography Council on Cardiac Sonography. J. Am. Soc. Echocardiogr., 2001, 14, 417–420.
Adams D. , 'Guidelines for the cardiac sonographer in the performance of contrast echocardiography: recommendations of the American Society of Echocardiography Council on Cardiac Sonography ' (2001 ) 14 J. Am. Soc. Echocardiogr. : 417 -420 .
Wei, K., Jayaweera, A. R., Firoozan, S., et al.: Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation, 1998, 97, 473–483.
Firoozan S. , 'Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion ' (1998 ) 97 Circulation : 473 -483 .
Vogel, R., Indermühle, A., Reinhardt, J., et al.: The quantification of absolute myocardial perfusion in humans by contrast echocardiography: algorithm and validation. J. Am. Coll. Cardiol., 2005, 45, 754–762.
Reinhardt J. , 'The quantification of absolute myocardial perfusion in humans by contrast echocardiography: algorithm and validation ' (2005 ) 45 J. Am. Coll. Cardiol. : 754 -762 .
Mollema, S. A., Nucifora, G., Bax, J. J.: Prognostic value of echocardiography after acute myocardial infarction. Heart, 2009, 95, 1732–1745.
Bax J. J. , 'Prognostic value of echocardiography after acute myocardial infarction ' (2009 ) 95 Heart : 1732 -1745 .