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  • 1 Debreceni Egyetem, Orvos- és Egészségtudományi Centrum Aneszteziológiai és Intenzív Terápiás Tanszék Debrecen Nagyerdei krt. 98. 4032
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A kóros mértékű szelénhiány mélyreható változásokat eredményez a sejtek oxidatív stressz elleni védekezésében, aminek többek között a keringési rendszer egyes betegségeinek és azok kockázati faktorainak kialakulásában is fontos szerep jut. A szepszis és az ezzel kapcsolatos kórképek igen összetett patomechanizmusának része a szabad oxigéngyökök fokozott képződése és csökkent eliminációja. A szelénpótlás a fenti betegségek megelőzésében és kezelésében nem új keletű gondolat, az utóbbi években született közlemények azonban ellentmondásos adatokat tettek közzé mindkét betegségcsoport vonatkozásában. A szerzők ezen a területen született legfontosabb kutatási eredmények összefoglalását tűzték ki célul a jelen összefoglaló írásakor. Orv. Hetil., 2013, 154, 1621–1627.

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