A hypertonia és az elhízás gyakorisága fokozatosan nő hazánkban. Magyarországon a hypertoniás férfiak 68,52%-a, míg a nők 78%-a elhízott. A magas vérnyomás és az elhízás külön-külön is a cardiovascularis morbiditás és mortalitás fontos kockázati tényezői. A fokozott szimpatikus aktivitás és a hypertonia kapcsolata jól ismert, ugyanakkor a haskörfogat és a test zsírtömege szignifikáns, pozitív korrelációban áll a szimpatikus aktivitással, amelyben a hyperleptinaemia is szerepet játszik. A renin-angiotenzin-aldoszteron rendszer fokozott aktivitása vascularis és renalis hatásai útján szintén vérnyomás-emelkedést okoznak. A fokozott szimpatikus aktivitással és a csökkent vagustónussal kísért autonóm idegrendszer egyensúlyzavara független és meghatározó kockázati tényezője a cardiovascularis eseményeknek, beleértve a hirtelen szívhalált is. Orv. Hetil., 2013, 154, 1736–1742.
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