Hazánkban az első és eddig egyetlen centrumként a Kaposvári Egyetem Egészségügyi Központjában üzemel multimodalitású PET/MR képalkotó berendezés. Összefoglaló közleményünk célja bemutatni a PET/MR képalkotás hazai klinikai alkalmazásának lehetőségeit, a tumoros és nem malignus kórképek diagnosztikájában szerzett kezdeti tapasztalatainkat, illetve az új hibrid képalkotó technológia további, jövőbeli alkalmazási területeinek ismertetése. Orv Hetil. 2018; 159(34): 1375–1384.
Borbély K. New challenges and perspectives in nuclear medicine imaging. [Újdonságok és új lehetőségek a nukleáris medicina képalkotásban.] Magy Onkol. 2014; 58: 232–238. [Hungarian]
Borbély K, Kásler M. Positron emission tomography in the 21th century. [Pozitronemissziós tomográfia a XXI. században.] Magy Tud. 2017; 178: 337–342. [Hungarian]
Trencsényi Gy, Barna SK, Garai I. Hybrid imaging: clinical evidence, opportunities. [Hibrid képalkotás: klinikai evidenciák, lehetőségek.] Orv Hetil. 2015; 156: 2110–2115. [Hungarian]
Repa I, Berényi E, Bogner P, et al. The fundamentals of magnetic resonance imaging (MRI) and its significance in the diagnosis of different disorders. Arch Oncol. 1995; 3: 9–12.
Kovács Á, Emri M, Opposits G, et al. Changes in functional MRI signals after 3D based radiotherapy of glioblastoma multiforme. J Neurooncol. 2015; 125: 157–166.
Emri M, Ésik O, Repa I, et al. Image fusion of different tomographic methods (PET/CT/MRI) effectively contribute to therapy planning. [A metszetképalkotó eljárások (PET/CT/MRI) képi fúziója hatékonyan elősegíti a terápiás döntést.] Orv Hetil. 1997; 138: 2919–2924. [Hungarian]
Eurostat. Healthcare resource statistics – technical resources and medical technology. Aavailable from: http://ec.europa.eu/eurostat/statistics-explained/index.php/Healthcare_resource_statistics_-_technical_resources_and_medical_technology#Further_Eurostat_information [accessed: March 11, 2018].
Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014; 32: 3059–3068.
Gergely L, Illés Á. Recent advances in the understanding and treatment of diffuse large B-cell lymphoma. [A diffúz nagy B-sejtes lymphoma modern szemlélete és kezelése.] Orv Hetil. 2016; 157: 1232–1241. [Hungarian]
Barrington SF, Mikhaeel NG, Kostakoglu L, et al. Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol. 2014; 32: 3048–3058.
Tóth Z, Zádori P, Lukács G, et al. Relapsing lymphoma provoking small intestinal intussusception assessed with PET/MR. Imaging Med. 2017; 9(3).
Grueneisen J, Sawicki LM, Schaarschmidt BM, et al. Evaluation of a fast protocol for staging lymphoma patients with integrated PET/MRI. PLoS ONE 2016; 11: e0157880.
NCCN Imaging Appropriate Use Criteria. NCCN Guidelines Version 1.2018 Hodgkin Lymphoma. Available from: https://www.nccn.org/professionals/physician_gls/pdf/hodgkins.pdf#Page=7 [accessed: March 08, 2018].
Hillengass J, Delorme S. Multiple myeloma: current recommendations for imaging. Radiologe 2012; 52: 360–365.
Varga G, Mikala G, Váróczy L, et al. Management of multiple myeloma in Hungary in 2016. [A myeloma multiplex megközelítése Magyarországon 2016-ban.] Orv Hetil. 2016; 157: 123–137. [Hungarian]
Piekarek A, Sosnowski P, Nowicki A, et al. Whole body MR in patients with multiple myeloma. Rep Pract Oncol Radiother. 2009; 14: 80–84.
Mesguich C, Fardanesh R, Tanenbaum L, et. al. State of the art imaging of multiple myeloma: comparative review of FDG PET/CT imaging in various clinical settings. Eur J Radiol. 2014; 83: 2203–2223.
Toth Z, Lukacs G, Rajnics P, et al. PET/MR in relapsed multiple myeloma. J Leuk. 2017; 5: 228.
Queiroz MA, Huellner MW. PET/MR in cancers of the head and neck. Semin Nucl Med. 2015; 45: 248–265.
Becker M, Zaidi H. Imaging in head and neck squamous cell carcinoma: the potential role of PET/MRI. Br J Radiol. 2014; 87: 20130677.
Kuhn FP, Hüllner M, Mader CE, et al. Contrast-enhanced PET/MR imaging versus contrast enhanced PET/CT in head and neck cancer: how much MR information is needed? J Nucl Med. 2014; 55: 551–558.
Covello M, Cavaliere C, Aiello M, et al. Simultaneous PET/MR head-neck cancer imaging: preliminary clinical experience and multiparametric evaluation. Eur J Radiol. 2015; 84: 1269–1276.
Ruhlmann V, Ruhlmann M, Bellendorf A, et al. Hybrid imaging for detection of carcinoma of unknown primary: a preliminary comparison trial of whole-body PET/MRI versus PET/CT. Eur J Radiol. 2016; 85: 1941–1947.
Sotoudeh H, Sharma A, Fowler KJ, et al. Clinical application of PET/MRI in oncology. J Magn Reson Imaging 2016; 44: 265–276.
Paspulati RM, Gupta A. PET/MR imaging in cancers of the gastrointestinal tract. PET Clin. 2016; 11: 403–423.
Ohliger MA, Hope TA, Chapman JS, et al. PET/MR imaging in gynecologic oncology. Magn Reson Imaging Clin N Am. 2017; 25: 667–684.
Rosenkrantz AB, Balar AV, Huang WC, et al. Comparison of coregistration accuracy of pelvic structures between sequential and simultaneous imaging during hybrid PET/MRI in patients with bladder cancer. Clin Nucl Med. 2015; 40: 637–641.
Bagade S, Fowler KJ, Schwarz JK, et al. PET/MRI evaluation of gynecologic malignancies and prostate cancer. Semin Nucl Med. 2015; 45: 293–303.
Kusmirek J, Robbins J, Allen H, et al. PET/CT and MRI in the imaging assessment of cervical cancer. Abdom Imaging 2015; 40: 2486–2511.
Mouthaan BE, Rados M, Barsi P, et al. Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe. Epilepsia 2016; 57: 770–776.
Theodore WH. Presurgical focus localization in epilepsy: PET and SPECT. Semin Nucl Med. 2017; 47: 44–53.
Catana C, Drzezga A, Heis WD, et al. PET/MRI for neurological applications. J Nucl Med. 2012; 53: 1916–1925.
Sacconi B, Raad RA, Lee J, et al. Concurrent functional and metabolic assessment of brain tumors using hybrid PET/MR imaging. J Neurooncol. 2016; 127: 287–293.
Marner L, Henriksen OM, Lundemann M. et al. Clinical PET/MRI in neurooncology: opportunities and challenges from a single-institution perspective. Clin Transl Imaging 2017; 5: 135–149.
Galldiks N, Langen KJ. Amino acid PET in neuro-oncology: applications in the clinic. Expert Rev Anticancer Ther. 2017; 17: 395–397.
Verburg N, Pouwels PJ, Boellaard R, et al. Accurate delineation of glioma infiltration by advanced PET/MR neuro-imaging (FRONTIER study): a diagnostic study protocol. Neurosurgery 2016; 79: 535–540.
NCCN Imaging Appropriate Use Criteria. NCCN Guidelines 1.2018 Central Nervous System Cancers. Available from: https://www.nccn.org/professionals/physician_gls/pdf/cns.pdf#Page=18 [accessed: March 09, 2018].
Bailey DL, Pichler BJ, Gückel B, et al. Combined PET/MRI: global warming – summary report of the 6th International Workshop on PET/MRI, March 27–29, 2017, Tübingen, Germany. Mol Imaging Biol. 2018; 20: 4–20.
Borbély K. New challenges and new potentials in the management of patients in oncology: PET/MRI clinical applications. [Újdonságok és új lehetőségek az onkológiai betegek terápiás vezetésében: PET/MR klinikai alkalmazások.] Magy Onkol. 2015; 59: 10–16. [Hungarian]
Bailey DL, Pichler BJ, Gückel B, et al. Combined PET/MRI: from status quo to status go. Summary report of the 5th International Workshop on PET/MRI, February 15–19, 2016, Tübingen, Germany. Mol Imaging Biol. 2016; 18: 637–650.
Bailey DL, Pichler BJ, Gückel B, et al. Combined PET/MRI: multi-modality multi-parametric imaging is here. Summary report of the 4th International Workshop on PET/MRI, February 23–27, 2015, Tübingen, Germany. Mol Imaging Biol. 2015; 17: 595–608.
Bailey DL, Antoch G, Bartenstein P, et al. Combined PET/MR: the real work has just started. Summary report of the 3rd International Workshop on PET/MRI, February 17–21, 2014, Tübingen, Germany. Mol Imaging Biol. 2015; 17: 297–312.
Deme D, Telekes A. Close follow-up of oncologic patients with imaging – advantage or disadvantage? [Onkológiai betegek szoros képalkotó követése – előny vagy hátrány?] Orv Hetil. 2016; 157: 1538–1545. [Hungarian]
Recommendations of the ICRP. ICRP Publication 26. Ann ICRP 1977; 1(3).