Authors:
János Fehér Semmelweis University Medical School 2nd Department of Medicine Szentkirályi u. 46 H-1088 Budapest Hungary

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Gabriella Lengyel Semmelweis University Medical School 2nd Department of Medicine Szentkirályi u. 46 H-1088 Budapest Hungary

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Interferons are glycoproteins of heterogeneous composition produced by the living cell as a part of the immune response to a viral infection. They were discovered exactly half a century ago. They possess antineoplastic, antiviral and immunomodulatory activities. The therapeutically used forms are denoted by Greek letters indicating their origin: leukocytes, fibroblasts, and lymphocytes for interferon-alpha, -beta and -gamma, respectively. Both natural and recombinant interferons have been used in human medicine. Connection with polyethylene glycol assures the prolonged effect of interferon preparations. Currently they are applied for the elimination of viruses in the therapy of chronic hepatitis B and C and for inhibiting the progression of neoplasms in oncology.

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Hungarian Medical Journal
Language English
Size  
Year of
Foundation
2007
Publication
Programme
ceased
Volumes
per Year
 
Issues
per Year
 
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1788-6139 (Print)
ISSN 1789-0403 (Online)