Authors:
Mamun-Al-Mahtab Bangabandhu Sheikh Mujib Medical University Department of Hepatology Dhaka Bangladesh

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Salimur Rahman Bangabandhu Sheikh Mujib Medical University Department of Hepatology Dhaka Bangladesh

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Mobin Khan Bangabandhu Sheikh Mujib Medical University Department of Hepatology Dhaka Bangladesh

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Belalul Islam Bangabandhu Sheikh Mujib Medical University Department of Hepatology Dhaka Bangladesh

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Abdullah Al Mahmud Bangabandhu Sheikh Mujib Medical University Department of Hepatology Dhaka Bangladesh

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Cirrhosis is a chronic liver disease characterized by diffuse fibrosis and nodule formation leading to distortion of normal liver architecture. The initial stimulus is hepatocyte necrosis. A wide variety of liver diseases can lead to cirrhosis, including viral hepatitis (B, C and D), alcohol, metabolic diseases (eg. haemochromatosis, Wilson’s disease, NASH, α1 anti-trypsin deficiency, type IV glycogenesis), cholestatic liver disease, auto-immune hepatitis, Budd-Chiari syndrome, drugs (eg. methotrexate, amiodarone), etc. The aetiology of cirrhosis remains unknown in a significant number of cases, giving rise to the entity of cryptogenic cirrhosis. In the UK, this figure stands between 5–10% [1]. In Bangladesh, the common causes of cirrhosis remain viral hepatitis (B and C) and NASH [2].

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Hungarian Medical Journal
Language English
Size  
Year of
Foundation
2007
Publication
Programme
ceased
Volumes
per Year
 
Issues
per Year
 
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1788-6139 (Print)
ISSN 1789-0403 (Online)