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  • 1 Bajcsy-Zsilinszky Hospital 1st Department of Medicine Bosnyák tér 14 1146 Budapest Hungary
  • | 2 Medical Faculty, University Košice 1st Department of Medicine Košice Slovakia
  • | 3 Semmelweis University 2nd Department of Medicine Budapest Hungary
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Increased prevalence of insulin resistance in patients with nonalcoholic fatty liver disease (NAFLD) has been demonstrated in various studies. However, there are only few references regarding the relationship between plasma insulin values or insulin sensitivity index and the biochemical severity of liver infiltration. The aim of this study was to examine a relationship between symptoms of the metabolic syndrome, i.e. insulin resistance, body weight and plasma lipoproteins and the laboratory parameters of liver fatty infiltration in patients with nonalcoholic fatty liver disease. There was found a significant positive correlation between plasma insulin and alaninaminotransferase ( r = 0.359, p < 0.01) and a significant positive correlation between plasma insulin and aspartateaminotransferase ( r = 0.42, p < 0.01). Additionally, a significant positive correlation was found between the index of insulin resistance (HOMA index) and alaninaminotransferase ( r = 0.637, p < 0.01) and a significant positive correlation between the index of insulin resistance (HOMA index) and aspartateaminotransferase ( r = 0.49, p < 0.01).

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Hungarian Medical Journal
Language English
Size  
Year of
Foundation
2007
Publication
Programme
ceased
Volumes
per Year
 
Issues
per Year
 
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1788-6139 (Print)
ISSN 1789-0403 (Online)

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