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  • 1 Semmelweis University 3rd Department of Internal Medicine Kútvölgyi út 4 H-1125 Budapest Hungary
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In this review the author collected examples from the literature for the verification of her hypothesis, that myelodysplasia might evolve from an unrevealed deficiency condition that had therefore been left uncorrected for a long time. That time might be long enough for a metabolic slip-out resulting in appropriate circumstances for a more primitive cell line to develop by gaining selection advantage. The author would like to emphasize the importance to diagnose and correct such deficiency conditions in time.

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