Browse

You are looking at 1 - 10 of 78,322 items for

  • All content x
Clear All

Abstract

Based on the current literature, the link between Achilles tendon moment arm length and running economy is not well understood. Therefore, the aim of this study was to further investigate the connection between Achilles tendon moment arm and running economy and the influence of Achilles tendon moment arm on the function of the plantarflexor muscle-tendon unit during running.

Ten male competitive marathon runners volunteered for this study. The participants ran on a treadmill at two running speeds: 3 and 3.5 m s−1. During running the oxygen consumption, lower leg kinematics, electrical activity of plantar flexor muscles, and fascicle behavior of the lateral gastrocnemius were measured simultaneously. On the second occasion, an MRI scan of the right leg was taken and used to estimate the Achilles tendon moment arm length.

There was a negative correlation between running economy and the body height normalized moment arm length at both selected speeds (r = −0.68, P = 0.014 and r = −0.70, P = 0.01). In addition, Achilles tendon moment arm length correlated with the amplitude of the ankle flexion at both speeds (r = −0.59, P = 0.03 and r = −0.60, P = 0.03) and with the electrical activity of the medial gastrocnemius muscle at 3 m s−1 speed (r = −0.62, P = 0.02). Our finding supports the concept that a longer moment arm could be beneficial for distance runners.

Open access

Abstract

In this study, the ability of microRNA-1906 (miR-1906) to attenuate bone loss in osteoporosis was evaluated by measuring the effects of a miR-1906 mimic and inhibitor on the cellular toxicity and cell viability of MC3T3‐E1 cells. Bone marrow-derived macrophage (BMM) cells were isolated from female mice, and tartrate-resistant acid phosphatase signalling was performed in miR-1906 mimic-treated, receptor-activated nuclear factor kappa-B (NF-κB) ligand (RANKL)-induced osteoclasts. In-vivo, osteoporosis was induced by ovariectomy (OVX). Rats were treated with 500 nmol/kg of the miR-1906 mimic via intrathecal administration for 10 consecutive days following surgery. The effect of the miR-1906 mimic on bone mineral density (BMD) in OVX rats was observed in the whole body, lumbar vertebrae and femur. Levels of biochemical parameters and cytokines in the serum of miR-1906 mimic-treated OVX rats were analysed. The mRNA expression of toll-like receptor 4 (TLR4), myeloid differentiation primary response 88 (MyD88), p-38 and NF-κB in tibias of osteoporotic rats (induced by ovariectomy) was observed using quantitative reverse-transcription polymerase chain reaction. Treatment with the miR-1906 mimic reduced cellular toxicity and enhanced the cell viability of MC3T3‐E1 cells. Furthermore, osteoclastogenesis in miR-1906 mimic-treated, RANKL-induced osteoclast cells was reduced, whereas the BMD in the miR-1906 mimic-treated group was higher than in the OVX group of rats. Treatment with the miR-1906 mimic also increased levels of biochemical parameters and cytokines in the serum of ovariectomised rats. Finally, mRNA expression levels of TLR4, MyD88, p-38 and NF-κB were lower in the tibias of miR-1906 mimic-treated rats than in those of OVX rats. In conclusion, the miR-1906 mimic reduces bone loss in rats with ovariectomy-induced osteoporosis by regulating the TLR4/MyD88/NF‐κB pathway.

Restricted access

Abstract

Concrete structures that are influenced by degradation, overloading, the thawing, and freezing cycles, corrosion of reinforced bars, should be repaired or strengthened. Each of the mentioned influences lead to decreased load-carrying capacity of the structure or its member. Exceeding the load-carrying capacity leads to mechanical damage of members or excessive deformation. The damaged member has to be strengthened to the required level of reliability and load-carrying capacity. There exist many types and methods of strengthening the columns. This research work deals with strengthening of columns by concreting a new layer of fiber concrete. When applying that type of strengthening, it is necessary to assure the contact between the old layer and the new one. The paper deals with analysis of different types of contacts and determination of their parametric values.

Restricted access
Pollack Periodica
Authors: Stepan Shapoval, Nadiia Spodyniuk, Vasyl Zhelykh, Volodymyr Shepitchak, and Pavlo Shapoval

Abstract

In line with the energy development strategy of Europe, it is necessary to implement energy efficient buildings, in which the external enclosures are converters of solar energy to thermal. Therefore, the purpose of the publication was the scientific substantiation and development of the solar heating system with the use of rooftop solar panels. Graphical and analytical dependences of the coefficient of thermal efficiency of the solar panel in heat supply system from the angles of solar radiation incoming and the density of the radiation flux were obtained. Analysis of the results showed that the coefficient of thermal efficiency of the solar panel without transparent coating with the placement of pipelines of the circulation circuit of the coolant over the heat absorber increases by 50%.

Restricted access

Abstract

Safety valves are the most important safety devices of the pressure system. For safety valves in the vast majority of cases in industrial environment, direct spring-loaded safety valves are used. The most important parameter of the equation of motion is the flow force. The main goal of the analysis was to compare the simulated flow forces with the measured results and validating the computational fluid dynamics model. Simulations were made in ANSYS 2019 R1 code for numerous fixed valve disk positions on different pressures. Results are in good agreement with the measured data.

Open access

Abstract

Concrete indeterminate flexural members represented by continuous beams reinforced with both fiber-reinforced polymers and steel bars in a way that allows for moment redistribution at failure are analyzed. The efficiency of introducing steel bars in the critical sections where plastic hinges are likely to form is evaluated in terms of reliability. Monte Carlo simulation and the concept of comparative reliability are both employed. Ultimately, the effect of different design parameters on the strength reduction factor is evaluated.

Open access

Abstract

The aim of this paper is to introduce the visual elements that may influence the lighting quality, and link them with the functioning of drug addiction institutes to understand the adequate design for each function and assure the well-being of the patient, therefore reduce their stress. The suggested strategy accords the qualitative and quantitative lighting design conditions to afford a complete reference for the forward study.

Open access

Abstract

Background and aims

Impulsiveness is an important factor in the pathophysiology of Internet gaming disorder (IGD), and regional brain functions can be different depending on the level of impulsiveness. This study aimed to demonstrate that different brain mechanisms are involved depending on the level of impulsiveness among patients with IGD.

Methods

Resting-state functional MRI data were obtained from 23 IGD patients with high impulsivity, 27 IGD patients with low impulsivity, and 22 healthy controls, and seed-based functional connectivity was compared among the three groups. The seed regions were the ventromedial prefrontal cortex (vmPFC), dorsolateral prefrontal cortex, nucleus accumbens (NAcc), and amygdala.

Results

Connectivity of the vmPFC with the left temporo-parietal junction (TPJ) and NAcc-left insula connectivity were significantly decreased in the patients with high impulsivity, compared with the patients with low impulsivity and healthy controls. On the other hand, amygdala-based connectivity with the left inferior frontal gyrus showed decreases in both patient groups, compared with the healthy controls.

Conclusion

These findings may suggest a potential relationship between impulsivity and deficits in reward-related social cognition processes in patients with IGD. In particular, certain interventions targeted at vmPFC-TPJ connectivity, found to be impulsivity-specific brain connectivity, are likely to help with addiction recovery among impulsive patients with IGD.

Open access

Abstract

With the continuous development of society and cities, people’s demand for urban public space is constantly changing, and the methods for public space renewal are becoming more and more diverse. As a flexible space renewal strategy, street art activities can not only partially update the space, increase the vitality of the space, but also improve the quality of the space and meet people’s needs. This paper first discusses the concepts and types of street art and clarifies the scope of research, Then, through the analysis of the role and impact of “street art activities intervening in urban space”, and finally summing up the relevant enlightenment, to create a favorable material environment for the future art intervention space.

Open access

Abstract

Castellated beams are made from a hot rolled steel I-section in a few steps. Firstly, the web of the parent I-section is cut in a particular zigzag pattern and the two halves are reconnected by welding to form a castellated beam with hexagonal openings. In other cases, a spacer plate is placed between the two halves to produce octagonal openings, which increase the section depth. Increasing the depth by adding spacer plates leads to web-post buckling. This study focuses on improving the castellated beam to obtain high strength with relatively low cost by placing a steel ring inside the octagonal openings to strengthen the weakest part, which is its web. The results show that the steel ring is effective in strengthening the web-post.

Restricted access