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Abstract

This paper sheds light on the treatment of initial gemination in Qassimi Arabic (QA), a Najdi dialect spoken in the Al-Qassim region in central Saudi Arabia, within the framework of Parallelism, an Optimality Theory (OT) model. The study concludes that initial geminates, which are non-actual surface forms in QA, result from the assimilation of the prefix /t-/ to stem-initial consonants of Arabic verb forms II and III, as well as hollow verbs, to avoid violation of the Obligatory Contour Principle (OCP). On the other hand, initial semisyllables, as moraic consonants, originate from initial gemination and consequently motivate prosthesis; that is, the purpose of prosthesis is to affiliate a semisyllable to the syllable node without causing violation of the Strict Layer Hypothesis (SLH). Sequences of assimilation of prefix /t-/ plus prosthesis do not occur simultaneously, whereas regressive assimilation feeds the prosthetic vowel [i], which, in turn, feeds the prosthetic glottal stop [ʔ] to concur with the Onset Principle. These sequences thus indicate transparent rule interactions, that is, feeding. Parallel OT is then successfully utilized to account for this type of phonological derivation.

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Abstract

Recently, the middle-income trap (MIT) has gained considerable attention – besides European countries, several African, Asian, and Latin-American developing countries are also affected. Many countries have remained in the middle-income bracket for decades, whilst only a few have advanced to high-income status. Felipe et al. in 2012 showed that an annual growth rate of at least 3.5 and 4.7% sustained for a period of 14 and 28 years is required respectively for upper-middle-income and lower-middle-income countries to escape the MIT. Economic growth is influenced by several factors including foreign aid received. Thus, in this study, we aim to answer the question of how aid affects economic growth in middle-income countries and whether aid may contribute to escaping the MIT. Focusing on the countries that have remained in the middle-income group between 1990 and 2017, our analysis confirms that aid contributes to economic growth; however, the impact is positive in the upper-middle-income countries and negative in the lower-middle-income countries. Aid is therefore, likely to be more effective in helping the upper-middle income countries to escape the MIT but not the lower-middle income countries.

Open access

Abstract

We analyse two reduplication processes in Saraiki, an Indo-Aryan language spoken in Pakistan. The two processes are only minimally different: the first type involves total reduplication and the second type involves overwriting with an initial consonant (“fixed segment reduplication”). The goal of the paper is to expose the difficulties of analysing both processes in a single grammar, i.e. with a single constraint hierarchy in Optimality Theory: we finally opt for an analysis based on allomorphy for the second type, to capture the morpheme-specific nature of the processes involved.

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Abstract

Purpose

Progesterone has been reported to inhibit the proliferation of breast cancer and osteosarcoma cells; however, its inhibitory mechanism has not yet been clarified. The aim of the present study was to clarify the effects of progesterone on apoptosis in breast cancer (MCF-7) and human osteosarcoma (MG-63) cells.

Materials and methods

In this experimental study the cytotoxic effect of progesterone was measured in MCF-7 and MG-63 cells exposed to different concentrations of progesterone using MTT assay, and effective concentrations were identified. The expression levels of the Bax, P53 and Bcl-2 genes were evaluated by real-time PCR, and caspase-3, 8 and 9 activity levels were determined using a colorimetric method. Hoechst staining and flow cytometry were used to confirm apoptosis. The data were statistically analyzed using one-way analysis of variance (ANOVA) and independent-samples t-test.

Results

Compared to the control group, we observed a significant increase in the expression levels of the Bax and P53 genes and the activity levels of caspase-3 and 9, and a significant decrease in the expression level of the Bcl-2 gene in MCF-7 and MG-63 treated with effective concentration of progesterone. The caspase-8 activity level did not change significantly in treated MG-63 but increased in treated MCF-7 cells. Hoechst staining and flow cytometry results confirmed apoptosis in the cells exposed to effective concentration of progesterone.

Conclusions

The cytotoxic effect of progesterone on breast cancer and osteosarcoma cells was mediated by apoptotic pathways. In this context, progesterone triggers the extrinsic and intrinsic apoptotic pathways in MCF-7 cells and induces the intrinsic apoptotic pathway in MG-63 cells.

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Abstract

The control of higher order linear system is one of the main fields of research area that has been studied for decades because of the difficulty in designing a controller for such systems. One of the best approaches to solve this problem is by reducing the order of the system into a second orders, based on this reduction many approaches can be proposed for controlling the higher order system, therefore many reduction methods are suggested and developed for this purpose, one of these methods is the Mixed Reduction Method (MRM). The first contribution of this paper is to improve the efficiency of MRM by using a flower optimization algorithm.

The second contribution of this paper lies in proposing a hybrid Neuro-Robust deadbeat controller using Matlab facilities to control higher order linear systems based on the optimized MRM. Where the robust deadbeat control algorithm is combined with a modified adaptive radial basis neural network to improve the robustness and efficacy of the deadbeat controller, which is partially lost when designing this controller for the higher order based on model reduction. The suggested radial basis function neural network has a simple design. The proposed control scheme assures the stability of the overall closed loop-controlled system; therefore, it can be applied to control any linear higher order systems. Results of different simulation examples show the efficiency of the proposed hybrid controller (Neuro-robust deadbeat) in tracking different reference signals compared to the robust deadbeat controller.

Open access

Summary

In this study, single-walled carbon nanotubes (SWNTs) were used to determine organochlorine pesticides (chlorothalonil and pentachloronitrobenzene) in water using dispersive solid-phase extraction (DSPE), followed by gas chromatography (GC). The optimal adsorption conditions were determined by analyzing the effect of adsorbent dosage, adsorption time, eluent type and volume, and elution time. Under the optimal conditions, a good linearity was obtained at concentrations from 10 to 400 μg L−1 with correlation coefficients ranging from 0.9991 to 0.9986. The limits of detection (LOD) for the two organochlorine pesticides were 0.025 and 0.049 μg L−1, and the limits of quantification (LOQ) were 0.080 and 0.156 μg L−1, respectively. The accuracy of the proposed method was evaluated by measuring the recovery of the spiked samples, which ranged from 82.5% to 110.5% at spiking levels of 0.5–10 μg L−1 with relative standard deviations lower than 5.6% (n = 6). This method was successfully applied to determine the target analytes in canal water, drinking water, and water taken from the inlets and outlets of a wastewater treatment plant. The results demonstrate that the developed method has great potential for determining the two organochlorine pesticides in water samples.

Open access
Progress in Agricultural Engineering Sciences
Authors: Mai Sao Dam, Lien Le Phuong Nguyen, Tamás Zsom, Géza Hitka, Ildikó Csilla Zeke and László Friedrich

Abstract

The aim of this work was to evaluate the effect of packaging perforation on quality of carrot slices during cold storage at 5 °C. Polyethylene bags with different number of perforations (3, 4, and 6) were used in this experiment. Headspace oxygen concentration, respiration, weight loss, surface color, firmness, pH, and soluble solid content were examined throughout storage. It was observed, that all the investigated packaging were effective in maintaining the quality of carrot slices compared to the control. There was no symptom of decay until 12 days. In addition, pH, soluble solid content, and firmness showed nonsignificant change. Moreover, weight loss of packed carrot slices was below 2% after 12 days of storage. Packed carrot had better appearance at the end of experiment (12 days) than that of control.

Open access

Abstract

Agricultural production is threatened by different invasive species, as their damage results in a serious loss of income. The aim of the research was the assessment of the swarming dynamics and damage of the western corn rootworm (WCR) adults and larvae. The experiment was carried out in monoculture fertilization long-term experiments and three maize hybrids compared for their reaction against WCR adult and larval damage under non-infested plots at different nitrogen levels. Differences among the hybrids have a lower effect on the damage of corn rootworm adults and larvae than the amount of applied nitrogen. The phosphorus-potassium are optimal levels, while nitrogen ranges from 0 to 300 kg and no nutrient supply took place in the control plots for 30 years. The number of adults located and feeding on the styles of the female flower recorded and the damage caused on the roots by larvae ranked on a modified Iowa scale. Nitrogen fertilization resulted in a change in the silking time. The lowest root damage observed in the case of the high nutrient treatment with an Iowa value of 3.18. The coincidence of the nourishment of adults and the egg-laying time with silking is a potential threat in terms of fertility. Based on the results, it found that the extent of root damage can be reduced through the optimal selection of the time and dose of nutrient supply, primarily that of nitrogen. In general, both larvae and adults can cause severe yield loss, but the method of control against them is different. The coincidence of the nourishment of adults and the egg-laying time with silking is a potential threat in terms of fertility.

Open access

Abstract

Background

Internet gaming disorder (IGD) is included in the DSM-5 as a provisional diagnosis. Whether IGD should be regarded as a disorder and, if so, how it should be defined and thresholded have generated considerable debate.

Methods

In the current study, machine learning was used, based on regional and interregional brain features. Resting-state data from 374 subjects (including 148 IGD subjects with DSM-5 scores ≥5 and 93 IGD subjects with DSM-5 scores ≥6) were collected, and multivariate pattern analysis (MVPA) was employed to classify IGD from recreational game use (RGU) subjects based on regional brain features (ReHo) and communication between brain regions (functional connectivity; FC). Permutation tests were used to assess classifier performance.

Results

The results demonstrated that when using DSM-5 scores ≥5 as the inclusion criteria for IGD subjects, MVPA could not differentiate IGD subjects from RGU, whether based on ReHo or FC features or by using different templates. MVPA could differentiate IGD subjects from RGU better than expected by chance when using DSM-5 scores ≥6 with both ReHo and FC features. The brain regions involved in the default mode network and executive control network and the cerebellum exhibited high discriminative power during classification.

Discussion

The current findings challenge the current IGD diagnostic criteria thresholding proposed in the DSM-5, suggesting that more stringent criteria may be needed for diagnosing IGD. The findings suggest that brain regions involved in the default mode network and executive control network relate importantly to the core criteria for IGD.

Open access