Browse our Medical Journals - AKJournals
Among all scientific traditions alive, medical publishing has a good chance to be the oldest. The first fully peer reviewed academic journal, “Medical Essays and Observations” was launched in 1731 by the Royal Society in Edinburgh. Since then, hundreds of medical journals have been published worldwide. Medical publication in Hungary started in 1857 when the famous physician, Markusovszky founded “Orvosi Hetilap”, which has been published since then every week (with short breaks during the world wars). It is now a most prestigious piece in AKJournals’ portfolio, listed in Journal Citation Reports, with a remarkable impact factor.
Medical and Health Sciences
Abstract
Background and aims
Unemployment rates are elevated among individuals with disordered gambling, yet the directionality of the relationship remains unclear. The present study investigated paid and unpaid unemployment as risk factors for future gambling disorder (GD).
Methods
The study employed a case-control design, including all adult Norwegians receiving a GD diagnosis within specialist health services from January 2008 to December 2018 (n = 5,131). These individuals were compared with age- and sex-matched controls from the general population (n = 30,164), as well as controls with somatic and psychiatric diagnoses (n = 30,476).
Results
Logistic regressions showed that those in the highest quartile of unpaid unemployment days had more than double the odds (odds ratio [OR] 2.23 (95% CI [1.96, 2.52]) of developing GD compared to those with no unpaid unemployment days. Similarly, higher levels of paid unemployment were also found to increase the odds for GD, with those in the highest quartile having an OR of 1.86 (95% CI [1.50, 2.28]) compared to those with no paid unemployment days. Moreover, an interaction analysis indicated that the association between paid unemployment days and GD was significantly stronger among men compared to women.
Conclusions
The present study suggests that both paid and unpaid unemployment constitute risk factors for GD. Programs aiming at obtaining and sustaining work have been found to improve health and future studies should examine if the risk for GD can be similarly mitigated.
Abstract
Background and Aims
Many jurisdictions are experiencing opioid epidemics. Opioid use disorder (OUD) often co-occurs with other psychiatric disorders including behavioral addictions like gambling disorder. However, little is known regarding the frequency and correlates of problematic pornography use (PPU) among people seeking treatment for OUD. Here we aimed to investigate PPU and its correlates in people seeking OUD treatment.
Method
From October 2018 to March 2020, 1,272 individuals seeking OUD treatment were screened for PPU by completing the Brief Pornography Screen (BPS), a 5-item instrument validated for assessing PPU. Self-reported data were used.
Results
Among the sample there were 707 (60%) males and 565 (40%) females. The mean age of participants was 37.9 ± 10.5 years (range 18–73), there were 707 (60%) males and 565 (40%) females, 14.4% (n = 183) exhibited low positive BPS scores (1 ≤ score ≤4), and 4.5% of the sample (n = 57) screened positive for PPU (BPS score ≥4). Individuals screening positive for PPU versus negative were mostly male (77%), scored higher on measures of impulsivity in the domains of positive urgency, negative urgency, and sensation-seeking and demonstrated more psychopathology on measures of substance use, psychotic symptoms, emotional lability, depression/functioning and self-harm.
Discussion and Conclusion
A minority of individuals seeking treatment for OUD screened positive for PPU. Among individuals with OUD, those screening positive (versus negative) for PPU were more impulsive and experienced more psychiatric symptoms, suggesting the need for additional investigation and screening for and addressing PPU in people with OUD.
Főszerkesztői előszó
Editor-in-Chief's greetings
Myelomás beteg 11 éves remissziót ért el másodvonalban adott lenalidomiddal – esetismertetés
Myeloma patient achieved 11 years of remission with second line lenalidomide
A myeloma multiplex egy rosszindulatú vérképzőszervi daganatos betegség, melynek kórlefolyását remissziók és relapszusok jellemzik. Egy betegünk kórtörténetét mutatjuk be, aki 5 évig kapott – klinikai vizsgálatban – másodvonalban lenalidomide + dexamethason kezelést és összesen 11 évig remisszióban volt. A beteg egy – szövettanilag nem verifikált – tüdődaganatban hunyt el, melynek kialakulásában inkább az erős dohányzás, kevésbé a tartós lenalidomide-kezelés játszhatott szerepet.
Abstract
Escherichia coli A382 was isolated in July 2024 from a positive blood culture obtained from the central venous catheter of a male patient undergoing chemotherapy at the Hospital of Volos, Thessaly, Greece. Whole-genome sequencing analysis revealed that the isolate A382 is E. coli belonging to the ST410 high-risk clone, which co-harbors the bla KPC-3 and bla SHV-182 genes on an IncX3 plasmid. It also harbors bla TEM-1 and has five replicons, as follows: IncX3, IncQ1, CoIRNAI, IncF1A, and IncFIB. Complete genome analysis revealed that E. coli A382 isolate carries a range of virulence factors (iutA, iucC, fimH, fdeC, yehA, yehD, yehC, yehB, cgs, ahha, ccI, hlyE, papC, irp2, fyuA, lpfA, and nlpl) and many other non-beta-lactam resistance determinants, including dfrA14 and sul2, but it is susceptible to aminoglycosides, nitrofurantoin, tigecycline, colistin and ceftazidime-avibactam. In conclusion in this study, we describe the phenotypic and genome characteristics of an extensively drug-resistant E. coli ST410.
Abstract
Background and Aims
This study sought to identify patterns of psychedelic use among American psychiatrists, to compare the demographic variables across categories of social proximity and personal use, and to determine how these categories influenced psychiatrists' attitudes towards drugs and people who use drugs.
Methods
Respondents (N = 180; mean age = 48.4 [SD = 16.2]; male = 65.5%; trainees = 24.1%) were recruited via email lists/listservs and personal networks (snowball sampling).
Results
Approximately one-third (32.8%) of psychiatrists reported Personal Connection (i.e., history of personal use and social connection) to psychedelics. Psychiatrists with Personal Connection to psychedelics were more likely to be younger (p = 0.006, ηp 2 = 0.057) and have fewer years of practice (p = 0.008, ηp 2 = 0.058). Almost all (92%) of those with No Connection to psychedelics were out of training, compared with only 8% of those in training. Those with Personal and Social Connection to psychedelics were more likely to disagree: that using illegal drugs is morally wrong (p < 0.001, ηp 2 = 0.28), that illegal drug users should go to prison (p < 0.001, ηp 2 = 0.15), are weak minded (p < 0.001, ηp 2 = 0.10), have no future (p < 0.001, ηp 2 = 0.12), are not well educated (F(2.0, 170) = 7.38. p < 0.001, ηp 2 = 0.08), are dishonest (p < 0.001, ηp 2 = 0.10), and that illegal drug users ‘make me angry’ (p < 0.001, ηp 2 = 0.10).
Conclusions
Personal and social connection to psychedelics is associated with decreased stigma towards drug use and people who use drugs. Future research should examine whether proximity to psychedelic use impacts other factors (e.g., empathy, therapeutic alliance) involved in psychiatry training and practice.
Hírek a hematológia világából
News from the world of hematology
Abstract
This article presents a rare case of intra-articular chondroma of the wrist joint diagnosed with the help of MR arthrography.
Állkapocsízületi diszfunkció kezelése skeletalis horgonylattal kombinált fogszabályozással
Skeletal anchorage combined orthodontic treatment of temporomandibular disorder
Temporomandibular disorder is the most common form of orofacial pain. Today it affects 15% of the adult population and 7% of adolescents. It is characterised by pain originating from the muscles and/or the temporomandibular joint and vocal symptoms accompanying jaw movements, as well as muscle fatigue, lockjaw and tooth wear. Chronic pain due to jaw dysfunction can lead to the deterioration of the patient’s psychological state and negatively affect their quality of life. As the temporomandibular joint is closely related to dentition, any modification of the existing bite must be taken into account from gnathological aspects. Orthodontic treatment can also be seen as a guided change of occlusion, and therefore the greatest possible attention should be paid to maintaining the stability of the temporomandibular joint (orthopaedic stability) when planning treatment, as this is closely related to joint health. If gnathological considerations are not met during treatment planning, altered bite position may lead to craniomandibular dysfunction; on the other hand, restoring stability may be an effective way to reduce symptoms. The aim of our case presentation and brief summary of the literature is to provide an overview of the pathology of temporomandibular joint complaints due to orthopaedic instability, the characteristics and symptomatology of stable and unstable occlusion, and the possible prevention and therapeutic options for temporomandibular joint dysfunction. Orv Hetil. 2024; 165(37): 1472–1477.
