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Acta Biologica Hungarica
Authors:
Z. Farkas
,
J. Márki-Zay
,
Judit Kucsera
,
Cs. Vágvölgyi
,
W. Golubev
, and
Ilona Pfeiffer

Wickerhamomyces anomalus VKM Y-159 strain produces two types of toxin designated as WAKT a and WAKT b, encoded by chromosomal genes. The WAKT a toxin is heat-labile, pronase sensitive acting in pH range 3–4 affecting on several yeasts including pathogenic Candida species while the WAKT b toxin is protease- and thermo-resistant, acting in pH range 3–7 on two species, Candida alai and Candida norvegica. The rapid decrease of the number of viable cells after toxin treatment demonstrates that both toxins have cytocidic effect.

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