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This paper describes the next stage in our development of self-optimising reactors. We demonstrate that the same reaction can be optimised for a series of different criteria including yield, space–time yield, E factor and a weighted yield function (the product of space–time yield and yield). In different experiments, we achieved 97.6% yield, space–time yield of 42.9 kg/L/h and E factors of 1.4 and 3.3 (including CO2) and the weighted yield, which gave a promising balance between yield, E factor and space–time yield.

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