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Journal of Flow Chemistry
Authors:
Klára Lövei
,
István Greiner
,
János Éles
,
Áron Szigetvári
,
Miklós Dékány
,
Sándor Lévai
,
Zoltán Novák
, and
György István Túrós

In medicinal chemistry, the development of synthetic procedures for the access of new heterocyclic systems as potential scaffolds is elementary. Herein, we report our results on the formation of small drug-like heterocycles, utilizing flow chemistry. This approach enables the extension of the reaction parameter window, including high-pressure/high-temperature or hazardous chemistry. In our work, various novel condensed tricyclic benzothiazoles fused with furo- and thieno-rings were synthesized applying a multistep continuous-flow protocol. The process includes two ring closure steps and a nitro group reduction step. Batch and telescoped continuous-flow syntheses were also designed and performed.

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The effect of two nonsteroidal anti-inflammatory drugs (carprofen and ketoprofen) on platelet adhesion and aggregation functions was evaluated by the PFA-100® analyser (Dade-Behring, CA, USA) using its collagen-adenosine diphosphate (ADP) and collagen-epinephrine (EPI) cartridges. The function of platelets was evaluated in 55 healthy dogs, in 7 dogs treated with ketoprofen and in 31 dogs treated with carprofen in a therapeutic dose for minimum 5 days. The therapeutic doses of carprofen had no effect on the closure time of PFA-100 (which is the marker of platelet function) but ketoprofen caused a significant increase when using collagen-EPI stimulation The closure times for both the healthy (control) and the treated dogs using EPI cartridges were often longer than the upper default cut-off point (300 sec) of the device. The PFA-100 analyser with collagen-ADP cartridges could be a useful tool for veterinary applications including the evaluation of platelet aggregation in dogs treated with NSAIDs. The upper cut-off point of PFA-100 might be extended.

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A kisiskolák és lehetőségeik

Small Schools and Their Opportunities

Educatio
Author:
Helga Andl

Összefoglaló. A tanulmány a kisiskolák magyarországi helyzetével foglalkozik, azok komplex társadalmi beágyazottságával, a hátrányos helyzet, a méltányosság és az inklúzió kérdéskörével, oktatáspolitikai és pedagógiai kérdésekkel. Területi és oktatás-statisztikai adatokra támaszkodva bemutatjuk az alacsony létszámmal működő baranyai iskolák egyes jellemzőit, az elmúlt másfél évtizedben lezajlott történéseket. Az intézményi kört érintők között hangsúlyosan jelenik meg az iskolabezárás, melynek folyamatát két iskola közelmúltban zajló megszűnésével foglalkozó esettanulmányunkra építve mutatjuk be. Működő gyakorlatokat keresünk arra, hogy a tanulók támogatásának, az inkluzív tanítási környezet kialakításának milyen lehetőségeit rejtik a – nem egy esetben összevont tanulócsoportos – kisiskolák.

Summary. This study attempts to uncover and understand the many different factors of small schools in Hungary: the role of disadvantage, how and if equity and inclusion can be realised, and the complex ways in which society perceives these institutions. For these social determinants are multifaceted, further aspects of pedagogy and education policy will be discussed too. Based on regional and education statistics related data, the paper explores the main features and the recent history of those primary schools in Baranya which operate with a low number of students. In this recent history of small schools, there is a clear emphasis on school closures, a process that we will focus on through our case study of two contemporary school closures in the area. With this analysis, our goal is to present several examples of embedded, functioning practices in small schools – many of which operate with multigraded study groups – that aim to support pupils and create an inclusive environment.

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Rectosigmoidealis tumor resectióját követő hasfali rekonstrukció osztályunkon

Abdominal wall reconstruction after resection of a rectosigmoid tumour

Magyar Sebészet
Authors:
Lóderer Zoltán
,
Kovács István
,
Kurán Gyula
,
Kovács Tamás
, and
Nagy Attila

. Eine vergleichende, retrospektive Studie an 432 Narbenbruchoperationen . Chirurg 74 638 – 45 . 2. JW Jones , GJ Jurkowich : 1989 Polypropylene mesh closure of

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A vena cava superior szindrómához társuló kétoldali zárt zugú glaucoma

Superior vena cava syndrome associated with bilateral angle closure glaucoma

Orvosi Hetilap
Authors:
Ágnes Elekes
and
Péter Vámosi

, 2022. 7 Durai I, Dhavalikar MM, Anand CP, et al. Bilateral, simultaneous, acute angle closure glaucoma in pseudophakia induced by chlorthalidone. Case Rep

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Abstract  

In this paper it will be constructed an abstract geometry will be called a triple space, which is defined in general sense by the closure theoretic definition of geometry “see [4]”. And it is proved that the category of triple spaces is isomorphic to the category of Steiner triple systems. And hence it could be shown that the class of Steiner triple systems which satisfy the geometric axiomI 3,

\documentclass{aastex} \usepackage{amsbsy} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{bm} \usepackage{mathrsfs} \usepackage{pifont} \usepackage{stmaryrd} \usepackage{textcomp} \usepackage{upgreek} \usepackage{portland,xspace} \usepackage{amsmath,amsxtra} \pagestyle{empty} \DeclareMathSizes{10}{9}{7}{6} \begin{document} $$\forall x_1 ,x_2 ,x_{3,} y;ify \in< x_1 ,x_2 ,x_3 > \backslash< x_1 ,x_2 > \Rightarrow x_3 \in< x_1 ,x_3 ,y >$$ \end{document}
((I3)) is exactly the class of all Steiner triple systems in which every triangle generate a planar subsystem.

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LetG be a real reductive Lie group, i.e., a Lie group whose Lie algebra is the direct product of a commutative and a semi-simple algebra. LetG 0 be the unit component ofG. We analyze the following question: if Φ is a continuous linear representation ofG over a finite dimensional complex vector spaceV then when can we find a scalar product onV so that the group Φ(G) become*-invariant with respect to it? In particular, ifG/G 0 is finite then we show that this is the case if and only if the same holds for the connected subgroup corresponding to the center ζ of the Lie algebra ofG and the latter condition is very easy to describe in terms ofdΦ/ζ. We discuss some related questions such as the relation between Cartan decompositions ofG and polar decompositions of Φ(G), the description of the closure of Φ(G), etc.

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Strictly speaking, the focus of the present essay is Petrarch's Sestina 22 (A qualunque animale alberga in terra) in Canzoniere; however, the peculiarities of the Petrarchan sestina will also be touched upon, including the relationship of Petrarch's poetic practice with that of his actual forerunners. In this respect, the provençal Arnaut Daniel and Dante will be mentioned. The essay aims at providing an analysis of the role end-words play in generating both meaning and theme. In addition, a special emphasis will be laid upon examining their sound effect and the functions these words carry in the given poetic idiom. Furthermore, a scrutiny will be given to the envoy and its relations to permutation and rhymes occurring at stanza-closures as well as to questions of versification and genre.

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The paper analyzes social mobility data for Hungary from surveys conducted by the Hungarian Central Statistical Office in 1983, 1992 and 2000. The main focus is put on testing Treiman’s modernization hypothesis that was posed in 1970 and is still widely cited today in the context of transition. The fitted models are graphical models based on directed acyclic graphs and the values of marginal log-linear parameters (as proposed in Rudas and Bergsma 2004) are used to gain insight into the strength of associations. The main findings include that the process of status-attainment seems to be basically unchanged for women, but some of the Treiman-like associations move toward greater social closure. That is our findings do not support the hypothesis of a trend toward increasing social fluidity in Hungary between the early 1980s and 2000.

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Abstract  

This paper investigates closure properties possessed by certain classes of finite subdirect products of prime rings. If ℳ is a special class of prime rings then the class ℳ of all finite subdirect products of rings in ℳ is shown to be weakly special. A ring S is said to be a right tight extension [resp. tight extension] of a subring R if every nonzero right ideal [resp. right ideal and left ideal] of S meets R nontrivially. Every hereditary class of semiprime rings closed under tight extensions is weakly special. Each of the following conditions imposed on a semiprime ring yields a hereditary class closed under right tight extensions: ACC on right annihilators; finite right Goldie dimension; right Goldie. The class of all finite subdirect products of uniformly strongly prime rings is shown to be closed under tight extensions, answering a published question.

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