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. 1 ). LC-MS/MS analysis of folic acid A Thermo Scientific Ultimate 3000 (Thermo Scientific, Massachusetts, USA) equipped with a Waters UPLC HSS T3, 1.8 μm, 2.1 × 150 mm column was used for quantitative analysis. 5 μL of reconstituted extract was

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(LC–MS) [18–20], ultra-performance liquid chromatography (UPLC) [21], high-performance thin-layer chromatography (HPTLC) [22–24], and spectrophotometry [25–30]. To our knowledge, the use of capillary electrophoresis (CE) to determine FTC and

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-to-noise ratio and good peak shape during bulk injection. The current reported lower limit of quantitation (LLOQ) is 0.5 pg mL −1 from 600 µL of plasma, with a method using UPLC separation, tandem quadrupole MS with UniSpray ionization, and selective solid

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-TOFMS and UPLC-QTOFMS . J Proteome Res 2009 ; 8 : 4844 – 50 . 10.1021/pr9004162 23. Pang Z , Wang G , Wang C , Zhang W , Liu J , Wang F . Serum metabolomics analysis of asthma in different inflammatory phenotypes: a cross

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of different origins. Our team is currently identifying unknown potential markers through ultra-high liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS), which will be a good supplement in the systematic quality control

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. ; Liu , X. ; Sun , Z. ; Wang , H. ; Jiang , J. A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection . J

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. ; Dong , F. ; Xu , J. ; Liu , X. ; Zhang , C. ; Li , J. ; Li , Y. ; Chen , X. ; Shan , W. ; Zheng , Y. Determination of difenoconazole residue in tomato during home canning by UPLC-MS/MS . Food Cont. 2012 , 23 ( 2 ), 542 – 546 . 19

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. L . ( 2011 ): UPLC-PDA-MS evaluation of bioactive compounds from leaves of Ilex paraguariensis with different growth conditions, treatments, and ageing .– Food Chem . 129 : 1453 – 1461 . 10.1016/j.foodchem.2011.05.112 Das , S ., Borah , M

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. https://doi.org/10.1016/j.jep.2021.114067 . 7. Hu , F. ; An , J. ; Li , W. ; Zhang , Z. ; Chen , W. ; Wang , C. ; Wang , Z. UPLC-MS/MS determination and gender-related pharmacokinetic study of five active ingredients in rat plasma after

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.5) and acetonitrile (70:30 v/v), gradient elution, flow 1.5 mL min −1 , temperature 25 °C. LC-UV 220 nm Pharmaceutical 13.0 50.0 [ 20 ] 2020 RP-UPLC C18 column (50 × 2.1 mm, 2.6 µm), mobile phase 0.4% aqueous formic acid solution added to 10 mM ammonium

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