Search Results
4,490.3 1.89 – 6 h 4,450.8 1.82 – 24 h 4,400.1 1.94 0.19 3 days 3,410.6 5.54 5.33 7 days 3,001.3 6.88 5.45 Caffeine 30 min 6,900.5 1.75 – 6 h 6,910.2 1.85 – 24 h 6,942.2 1.66 0.115 3 days 6,805.1 3.99 7.56 7 days 6,700.9 5.34 6.22 Phenylepherine 30
another NH proton at position 5. This suggested confirming the presence of one NH and one NH2 group in the molecule. The presence of nOe cross-correlations between H1/H10, H3/H5, H6/H16, H12/H18, and H13/H18 along with the HMBC correlations between H18/C17
leaves. The laxative, wound healing, antioxidant, anti-inflammatory, immunostimulant, antimicrobial, antitumor, analgesic and neuroprotective effects of A. vera plant have been reported [ 3–7 ]. Allantoin is a chemical compound with formula C 4 H 6 N 4
. Nobiletin and tangeretin were administered intravenously (iv) 1 mg kg −1 and orally (po) 5 mg kg −1 , respectively, with 6 rats in each group, for a total of 24 rats. At 0.083 3, 0.5, 1, 2, 3, 4 h, 6, 8 and 12 h time points, 0.3 mL blood was collected from
1/2 z h 6.2 ± 2.0 7.0 ± 5.9 CL z/F L/h/kg 2.9 ± 0.5 35.1 ± 12
2.5 ± 1.4 7.8 ± 3.5 t 1/2 z h 6.2 ± 4.8 6.7 ± 3
7 days 12.92 1.81 12.28 −7.05 9.55 −6.54 Room temperature for 15 h
.128 ± 0.4 4.3 MRT (0-∞) h 9.316 ± 0.55 5.9 t 1/2 z h 4.149 ± 0.92 22.2 T max h 6 ± 0 0 Vz/F L kg −1 2.797 ± 0.64 22.9 CLz/F L h −1 kg −1 0.468 ± 0.05 10.5 C max ug L −1 1,879.1 ± 340.72 18.1 Conclusion A reliable and high-throughput UPLC-MS/MS method was
-BUTINACA after oral administration ( n = 6) Parameters Unit Oral AUC (0-t) ng mL −1 *h 2923.0 ± 523.5 AUC (0-∞) ng mL −1 *h 3004.2 ± 570.4 MRT (0-t) h 6.3 ± 0.7 MRT (0-∞) h 7.1 ± 0.8 t 1/2z h 4.4 ± 1.1 T max h 2.8 ± 0.5 C max ng mL −1 616.9 ± 154.5 AUC (0-t
and noscapine in rat plasma are shown in Fig. 3 . The half-lives ( t 1/2z ) of papaverine and noscapine in the rats after intravenous administration were 1.0 ± 0.2 h, 6.2 ± 2.2 h, respectively, while the t 1/2z after oral administration were 2.4 ± 0
