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effectiveness there is a need for the development of new treatments ( Cloitre, Stolbach, Herman, van der Kolk, Pynoose, Wang & Petkova, 2009 ). Pharmacologically assisted psychotherapy has been shown to be beneficial. MDMA

Open access

, only two investigators for MDMA-assisted psychotherapy studies are women of color, Marcela Ot'alora, M.A., L.P.C. (Latina) and Monnica Williams, Ph.D. (Black) and trainees in psychedelic-assisted therapy programs remain overwhelmingly White. Notably, in

Open access
Journal of Psychedelic Studies
Authors:
Mark Cornfield
,
Susan McBride
,
Joseph T. La Torre
,
Daniel Zalewa
,
Jade Gallo
,
Mehdi Mahammadli
, and
Monnica T. Williams

more clinical studies are needed. Psychedelic substances and non-classic psychedelic compounds, such as MDMA and ketamine, may possess empathogenic qualities, therefore it is possible that such agents could be useful in facilitating couples therapy

Open access

, and psilocybin are serotonergic hallucinogens that operate primarily on the 5-hydroxytryptamine 2A receptors (5-HT 2A ), in the brain ( Nichols, 2016 ). Substances like the dissociative ketamine, entactogens such as MDMA, and polydrug admixtures such

Open access

Psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) as well as related compounds (e.g., 3,4-Methyl​enedioxy​methamphetamine; MDMA) have preliminarily demonstrated a high level of safety and efficacy for treating psychiatric

Open access

psychedelic research, popularizing of use of non-ordinary states of consciousness to aid in PTSD, anxiety and depression, end of life and a growing sense that the use of substances like MDMA, psilocybin and others may become mainstream approaches to treating

Open access
Journal of Psychedelic Studies
Authors:
Stacey B. Armstrong
,
Adam W. Levin
,
Yitong Xin
,
Jordan C. Horan
,
Jason Luoma
,
Paul Nagib
,
Brian Pilecki
, and
Alan K. Davis

-classic” (e.g., 3,4-methylenedioxymethamphetamine (MDMA). Classic psychedelics act at the serotonin 2A receptor (5-HT 2A R) as agonists or partial agonists ( Johnson, Hendricks, Barrett, & Griffiths, 2019 ), and the psychological mechanisms for non

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their mental health. When asked about their use of other psychoactive substances, 64% had used psilocybin, 45% had used MDMA, and 32% had used LSD at least once. Participants who reported using these drugs commonly stated that they used them to support

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Psychedelic-Assisted Therapies (PATs). The most empirically substantiated PAT for trauma incorporates an 18-session protocol that uses MDMA as the active agent in up to three separate sessions ( Mitchell et al., 2023 ). In addition, preliminary studies offer

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decriminalization, groundbreaking legalization of therapeutic psilocybin, pending approval of MDMA for Post-Traumatic Stress Disorder (2003), and bills in progress legalizing personal possession and use, the expansion of psychotherapeutic approaches and applications

Open access