Search Results

You are looking at 11 - 20 of 441 items for :

  • "pharmacokinetics" x
  • Refine by Access: All Content x
Clear All

significant inhibitory activities against five plant pathogenic fungi Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sclerotinia sderotiorum, and Fusarium oxysportium. Pharmacokinetics is a discipline that quantitatively studies the laws of drug

Open access
Acta Chromatographica
Authors: Lianguo Chen, Qingwei Zhang, Yijing Lin, Xiaojie Lu, Zuoquan Zhong, Jianshe Ma, Congcong Wen, and Cheng Ding

pharmacology of hapepunine, it was necessary to investigate its pharmacokinetics. Pharmacokinetic study was a discipline that quantitatively investigates the absorption, distribution, metabolism, and excretion of drugs in vivo [ 6 , 7 ]. Therefore, it was

Open access
Acta Chromatographica
Authors: Peiwu Geng, Jing Zhang, Bingbao Chen, Qianqian Wang, Shuanghu Wang, and Congcong Wen

fast bioanalytical method to characterize the pharmacokinetics. Figure 1. Chemical structure of dauricine (a) and daurisoline (IS, b) There was a liquid chromatography method

Open access
Acta Chromatographica
Authors: Aixia Han, Guanyang Lin, Jinzhang Cai, Qing Wu, Peiwu Geng, Jianshe Ma, Xianqin Wang, and Chongliang Lin

, corynantheine, and dihydrogen coinine [ 8 , 9 ]. The study of pharmacokinetics quantitatively investigates the absorption, distribution, metabolism, and excretion (ADME) of drugs in vivo, as well as the underlying mechanism, interaction within complex

Open access

; Bachmann et al . , 2018 ), endometritis ( Amiridis et al . , 2003 ), respiratory infections ( Funaki et al . , 2001 ), and septicaemia ( Thomas et al . , 2004 ). The pharmacokinetics of cefquinome were previously estimated in sheep ( Corum et al . , 2019

Restricted access

[ 9–20 ]. Compared to HPLC and LC-MS/MS, UPLC-MS/MS is faster, possessing significant advantages in the investigation on pharmacokinetics of drugs [ 21–28 ]. Meanwhile, the powerful separation and analysis capacity is applicable to analyze the in vivo

Open access

 mg/kg) [ 23 ]. However, the retention time of psoralidin in two methods is more than 14 min, and there is no pharmacokinetic report after intragastric administration of psoralidin. In fact, as for traditional Chinese medicines (TCMs), it is of more

Open access

representative bioactive compounds of Fuzi, are directly related to the pharmacological effects and toxicological effects of YGY in vivo. Pharmacokinetic (PK) studies are useful to elucidate and predict the efficacy and toxicity of drugs and helpful in

Open access

/reperfusion-induced delayed neuronal damage in mice [ 10 ]. With so many great effects, it shows promising application. However, further research is still in need to confirm the relative effectiveness and achieve the pharmacokinetic characteristics of eupatilin. Hence

Open access

these diseases [ 13 ]. The trade name for apremilast is Otezla, and it is manufactured by Celgene Corporation (Summit, NJ, USA) as 10-mg, 20-mg, and 30-mg tablets [ 14 ]. As a new oral drug, a pharmacokinetic study is required to describe its disposition

Open access