Authors:Edit Urbán, Márió Gajdács, and Attila Torkos
Ambulatory Health Care Data . https://www.cdc.gov/nchs/ahcd/index.htm (Accessed: 21st of January, 2019) . 7. Puglisi S , Privitera S , Maiolino L , Serra A , Garotta M , Blandino G , Bacteriological findings and antimicrobialresistance
Authors:V. Szott, B. Reichelt, T. Alter, A. Friese, and U. Roesler
antimicrobialresistance in zoonotic and indicator bacteria from humans, animals and food in 2017 . EFSA J 2019 ; 17 : e05598 . 19. Sokovic M , Glamoclija J , Marin PD , Brkic D , van Griensven LJ . Antibacterial effects of the essential oils
Authors:E. Sapi, K. Gupta, K. Wawrzeniak, G. Gaur, J. Torres, K. Filush, A. Melillo, and B. Zelger
antimicrobial treatments [ 40 ]. Diabetic foot ulcers show polymicrobial infection involving S. aureus , P. aeruginosa , and E. coli at the site of infection, slowing the healing process and, in some cases, leading to antimicrobialresistance [ 83 ]. These
Authors:I. Damjanova, Á. Tóth, É. Kenesei, M. Köhalmi, P. Szántai, M. Füzi, and J. Pászti
Molecular epidemiology and genetic features of an extended-spectrum β-lactamase (ESBL) producing Klebsiella pneumoniae epidemic clone (KP-EC) with elevated ciprofloxacin MIC (minimum inhibitory concentration) values from multiple nosocomial outbreaks and sporadic cases between 2006 and 2008 in Hungary were investigated.
As a result of continuous monitoring of ESBL-producing KP-ECs, 27 isolates collected from five healthcare facilities were selected for macrorestriction profile analysis by PFGE (pulsed field gel electrophoresis). Of these, 12 strains were isolated from adult inpatients, while 15 strains were from newborns. The MIC values for several antibiotics were determined by agar dilution technique. Molecular typing was further performed by PCR (polymerase chain reaction) and sequencing of several antibiotic resistance genes, plasmid profile analysis, transfer of resistance determinants and multilocus sequence typing (MLST).
All isolates showed moderate resistance to ciprofloxacin (MICs ranged from 0.5 to 8 mg L−1). PFGE revealed the existence of only one genetic cluster defined as EC IV. PstI digestion of plasmid DNA revealed two highly diverse restriction patterns in “adult” and “newborn” isolates corresponding to plasmids from the Hungarian Epidemic Clone and plasmids isolated from a neonatal nosocomial outbreak in 1998, respectively. Sequence analysis of b-lactamase genes from plasmids of 14 selected isolates detected blaSHV-2a in strains isolated exclusively from newborns and blaCTX-M-15 in strains isolated exclusively from adult inpatients. MLST established that strains of the PFGE cluster belonged to a novel sequence type ST274.
ESBL-producing K. pneumoniae isolates belonging to the novel sequence type ST274 appeared in the newborn and adult hospital settings in Hungary and acquired SHV-2a or CTX-M-15 type enzymes, respectively. Thus, a new antimicrobial resistance strategy for successful conformation to distinct hospital settings was found.
, G. , Negeri , C. & Kassu , A. ( 2006 ): A five-year antimicrobialresistance pattern observed in Shigella species isolated from stool samples in Gondar University Hospital, northwest Ethiopia . Ethiop. J. Health Dev