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The effect of group-administered psilocybin on psychological flexibility and outcomes Research on the efficacy of psychedelic-assisted therapy (PAT) has expanded rapidly in the last decade. The FDA has designated breakthrough therapy status for MDMA

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therapies for psychiatric disorders: Psilocybin and MDMA . The Lancet Psychiatry , 3 , 481 – 488 . https://doi.org/10.1016/s2215-0366(15)00576-3 . Moreno , F. A. , Wiegand , C. B. , Taitano , E. K. , & Delgado , P. L. ( 2006 ). Safety

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​enedioxy methamphetamine (MDMA) for synergistic MDMA effects is well known and referred to as “candyflipping” ( Chary, Yi, & Manini, 2018 ; Schechter, 1998 ). However, combining LSD and other stimulants appears to be less common ( Licht et al., 2012 ). In the case of

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Journal of Psychedelic Studies
Authors:
Beatriz Labate
,
Anna O. Ermakova
,
Jordan Sloshower
,
Nicole Galvão-Coelho
,
Fernanda Palhano-Fontes
,
Henrique Fernandes Antunes
,
Glauber Loures de Assis
,
Clancy Cavnar
,
Draulio de Araújo
, and
Sidarta Ribeiro

attests to the danger of ayahuasca to public health. But the CSA needs to be seen as a political document that is subject to change and questioning. The recent discussions about psilocybin, MDMA, and other psychedelics make it clear how it is a document

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). MDMA-Assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study . Nature Medicine , 27 ( 6 ), 1025 – 1033 . https://doi.org/10.1038/s41591-021-01336-3 . Mithoefer , M. C. , Mithoefer , A. T. , Feduccia , A. A

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recently defined by the journal Psychedelic Medicine as serotonergic agonists that expand brain network connectivity by activating 5-HT2A receptors. They include classic psychedelics (psilocybin, mescaline, DMT, and LSD) as well as ketamine and MDMA

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, A. , Jerome , L. , Mithoefer , A. , Wagner , M. , Walsh , Z. , Hamilton , S. , Yazar-Klosinski , B. , Emerson , A. & Doblin , R. ( 2019 ). MDMA-Assisted psychotherapy for treatment of PTSD: Study design and rationale for phase 3

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“relive the drug taking experience in their imagination” ( Baumann, 1970 , p. 20) with similar findings indicated more recently in a group of 3,4-Methylenedioxymethamphetamine (MDMA) users ( Hastings, 2006 ) suggesting the re-accessing of psychedelic

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) reported on the efficacy of MDMA and psilocybin in treating symptoms of PTSD and depression, but noted that confounders, patient bias, and challenges associated with blinding remain. Recent articles provide a valuable analysis of methodological problems

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-drug interactions between psychiatric medications and MDMA or psilocybin: A systematic review . Psychopharmacology , 239 , 1945 – 1976 . https://doi.org/10.1007/s00213-022-06083-y . 10.1007/s00213-022-06083-y

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