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psychedelic compounds such as 3,4-methylenedioxymethamphetamine (MDMA) and ketamine for treating psychological disorders, psilocybin for the treatment of depression has the most extensive and robust empirical support. As with many mental disorders, depression

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, 2021 , 39:53). This confidence in the notion that psychedelics will radically minimize interpersonal harms reappears in another frequent slogan: “I believe that fully globalized access to MDMA-assisted therapy can lead to a world of net-zero trauma by

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maltreatment ( Healy, Lee, & D’Andrea, 2021 ). This finding suggests that psychedelics may reduce the impact of a history of adverse childhood experiences (ACEs) on distress in adulthood. In addition, a randomized, double-blind, placebo-controlled study of MDMA

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findings are consistent with prior studies showing that MDMA, a serotonergic psychedelic, has been shown to produce significant PTSD symptom reduction ( Ot’alora G et al., 2018 ). Additionally, animal studies have shown that ibogaine was effective in

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The effect of group-administered psilocybin on psychological flexibility and outcomes Research on the efficacy of psychedelic-assisted therapy (PAT) has expanded rapidly in the last decade. The FDA has designated breakthrough therapy status for MDMA

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therapies for psychiatric disorders: Psilocybin and MDMA . The Lancet Psychiatry , 3 , 481 – 488 . https://doi.org/10.1016/s2215-0366(15)00576-3 . Moreno , F. A. , Wiegand , C. B. , Taitano , E. K. , & Delgado , P. L. ( 2006 ). Safety

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​enedioxy methamphetamine (MDMA) for synergistic MDMA effects is well known and referred to as “candyflipping” ( Chary, Yi, & Manini, 2018 ; Schechter, 1998 ). However, combining LSD and other stimulants appears to be less common ( Licht et al., 2012 ). In the case of

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Journal of Psychedelic Studies
Authors:
Beatriz Labate
,
Anna O. Ermakova
,
Jordan Sloshower
,
Nicole Galvão-Coelho
,
Fernanda Palhano-Fontes
,
Henrique Fernandes Antunes
,
Glauber Loures de Assis
,
Clancy Cavnar
,
Draulio de Araújo
, and
Sidarta Ribeiro

attests to the danger of ayahuasca to public health. But the CSA needs to be seen as a political document that is subject to change and questioning. The recent discussions about psilocybin, MDMA, and other psychedelics make it clear how it is a document

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). MDMA-Assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study . Nature Medicine , 27 ( 6 ), 1025 – 1033 . https://doi.org/10.1038/s41591-021-01336-3 . Mithoefer , M. C. , Mithoefer , A. T. , Feduccia , A. A

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recently defined by the journal Psychedelic Medicine as serotonergic agonists that expand brain network connectivity by activating 5-HT2A receptors. They include classic psychedelics (psilocybin, mescaline, DMT, and LSD) as well as ketamine and MDMA

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