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A diabetes mellitus kapcsolata a depresszióval, a szorongással és az életminőséggel

Association of diabetes mellitus with depression, anxiety and quality of life

Orvosi Hetilap
Authors:
Beatrix Rafael
,
Lilla Horváth
,
Flóra Szemán
,
Tamás Várkonyi
,
Csaba Lengyel
, and
Anett Dávid

. Diabet Med. 2008; 25: 1324–1329. 8 Bai X, Liu Z, Li Z, et al. The association between insulin therapy and depression in patients with type 2 diabetes mellitus: a meta

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Cseh K., Winkler G.: A zsírszöveti „endokrin” szabályozó rendszer és szerepe az inzulinrezisztencia kialakulásában. In Halmos T., Jermendy, Gy. (szerk.): Diabetes mellitus. Elmélet és klinikum. Medicina Kiadó, Budapest, 2002, 98

Open access
Orvosi Hetilap
Authors:
Judit Nádas
,
Zsuzsanna Putz
,
József Fövényi
,
Zsolt Gaál
,
András Gyimesi
,
Tibor Hídvégi
,
Nóra Hosszúfalusi
,
Gyula Neuwirth
,
Tamás Oroszlán
,
Pál Pánczél
,
Győző Vándorfi
,
Gábor Winkler
,
István Wittmann
, and
György Jermendy

. 2007 11 289 296 Gerő L.: Az 1-es típusú diabetes mellitus patomechanizmusa, tünettana és kezelési

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2009 32 193 203 A diabetes mellitus kórismézése, a cukorbetegek kezelése és gondozása felnőttkorban. A Magyar Diabetes Társaság

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Introduction Diabetes mellitus type 2 (DM-2) is caused by environmental elements, lifestyle and genetic factors. Numerous studies have been conducted to explore the molecular pathology of diabetes through molecular studies by

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Sheehan, M. T.: Current therapeutic options in Type 2 Diabetes Mellitus: A practical Approach. Clin. Med. Res., 2003, 1 , 189–200. Sheehan M. T. Current therapeutic options in

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Plant drug mixtures are widely used in the adjuvant therapy of type 2 diabetes mellitus for the prevention of complications. The drug mixtures generally contribute to the efficiency of the therapy and may also reduce undesirable side effects. Two herbal extracts (lyophilized aqueous extracts of plant drug mixtures 1: Myrtilli folium, Phaseoli fructus sine seminibus and 2: Myrtilli folium, Phaseoli fructus sine seminibus, Salviae folium ) were investigated in in vitro rat models. The content of bioactive constituents (polyphenol, flavonoid and vitamin C) in plant drug mixtures and lyophilized samples was evaluated. The antioxidant activity of lyophilized extracts was determined by measuring the ferric reducing ability of the plant, Fe 2+ induced lipid peroxidation (LPO) in rat brain homogenates and NADPH (β-nicotinamide adenine dinucleotide phosphate reduced form) induced LPO in cerebral microsomes. The antioxidant activity of lyophilized extracts was compared to that of quercetin and rutin. Both teas of lyophilized extracts had significant reducing ability (2694 and 2771 μmol/l) and inhibited LPO (IC 50 28.0 and 20.6 μl in NADPH induced LPO, 17.3 and 8.7 μl in Fe 2+ induced LPO). The high concentration of polyphenol/flavonoid (12.38–13.00 and 1.45–5.22 g/100 g, respectively) and vitamin C (0.099–0.165 g/100 g) in the herbal extracts is related to their significant antioxidant properties. The tea mixtures have significant nutritional value, since the consumption of 2 or 3 cups of tea a day covers 50% of the daily requirement of vitamin C and it is also relevant polyphenol source. The high polyphenol/flavonoid content may restore the redox imbalance and contribute to the prevention of diabetic complications.

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Orvosi Hetilap
Authors:
Orsolya Máté
,
Ildikó Ábrahám
,
Melinda Cserép
,
Lilla Grundmann
,
Zsófia Lendvai
,
Bea Pászthy
, and
Péter Tóth-Heyn

–16. 2 Kakleas K, Kandyla B, Karayianni C, et al. Psychosocial problems in adolescents with type 1 diabetes mellitus. Diabetes Metab. 2009; 35: 339

Open access

Tamás, Gy.: Insulin treatment. In: Diabetes mellitus – clinical aspects. Eds.: Halmos, T., Jermendy, Gy. [Inzulinkezelés. In: Diabetes mellitus – a cukorbetegség klinikai vonatkozásai.] Medicina

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Abstract  

Four plant parts (leaves, roots, fruits and seeds) of twenty samples of sixteen antidiabetic herbs including three commercially marketed capsules have been analyzed for 6 minor (Na, K, Ca, Cl, Mg, and P) and 21 trace (As, Ba, Br, Ce, Co, Cr, Cs, Cu, Eu, Fe, Hg, La, Mn, Rb, Sb, Sc, Se, Sm, Th, V and Zn) elements by instrumental neutron activation analysis (INAA). Further, Ni, Cd and Pb contents were determined by AAS. Elemental data were validated by simultaneously analyzing reference material (RM), MPH-2 Mixed Polish Herbs. Several elements such as Cr and V (1–2 μg/g), Rb (10–40 μg/g), Cs (80–300 ng/g), Se (∼100 ng/g) and Zn (25–60 μg/g) play an important role in diabetes mellitus. Interelemental linear correlations have been observed for Cu vs. Zn (r = 0.89) and Rb vs. Cs (r = 0.87). K/P ratio varies in a narrow range with a mean value of 6.2 ± 1.4. Toxic elements As and Hg were found in <1 μg/g whereas Cd and Pb were in ∼5 μg/g and <10 μg/g, respectively.

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