developed for the quantification of dauricine in beagle dog plasma to characterize the pharmacokinetics [ 8 ]. There, a sensitive and selective liquid chromatography–tandemmassspectrometry method had been developed and validated for simultaneous
Authors:Xi Bao, Bingge Huang, Yiting Mao, Zhiguang Zhang, Yunfang Zhou, Congcong Wen, and Quan Zhou
mechanistic study and target identification.
Rapid, simple, and reliable high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and liquid chromatography with electrospray ionization tandemmassspectrometry (LC–ESI-MS/MS) methods
Authors:Jianwei Han, Wenbo Zhu, Ling Yu, Yajun Chen, Gaosong Wu, and Zhibin Wang
could be used for the comparison of the pharmacokinetic characteristics between CCSG and calycosin. In this study, we used ultra-high performance liquid chromatography tandemmassspectrometry (UHPLC-MS/MS) combining multiple reaction monitoring (MRM
Authors:Lianguo Chen, Haiya Wu, Xiaoting Tu, Yi Zhao, Yanyan Jiang, Congcong Wen, and Yue Luo
and rapid ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method for the simultaneous determination of atractylenolide I, II, and III in rat plasma [ 1 ]. Plasma samples were processed by liquid–liquid extraction with
Authors:Binbin Chen, Haiyan Lyu, Xiangzhen Xu, and Chen Wang
years, liquid chromatography–mass spectrometry (LC–MS) or liquid chromatography–tandemmassspectrometry (LC–MS/MS) has become a mature technique with many applications to various biological matrixes in cortisol and cortisone analyzing fields [ 11 – 18
Authors:S.-Y. Shao, Y. Ting, J. Wang, J. Sun, and X.-F. Guo
use a rapid method to determine the true molecular structure of such compounds. Mass spectrometry (MS) has been widely used for the structural determination of flavonoids [ 21 , 22 ]. Liquid chromatography combined with tandemmassspectrometry (LC
pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min.
In this paper, an ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method with an
Authors:Jianbo Li, Zheng Yu, Cheng Han, Zhening Wang, Yujie Hu, Congcong Wen, and Chongliang Lin
, distribution, and metabolism, and the bioavailability was greatly improved.
Ultra-high performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) combined technology combines the high resolution of liquid chromatography with the high
Authors:Qinghua Weng, Lianguo Chen, Luxin Ye, Xiaojie Lu, Zheng Yu, Congcong Wen, Yichuan Chen, and Gang Huang
Compared with capillary-zone electrophoresis, HPLC, and LC–MS, an ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method was more sensitive, high throughput, and time saving [ 16 – 20 ]. In this study
Authors:Yongxi Jin, Yuyan Chen, Jiawen Liu, Xi Bao, Yinghao Zhi, Congcong Wen, and Wenzong Zhu
massspectrometry (UPLC–MS/MS) reported for the determination of ebeiedinone. To the best of our knowledge, the pharmacokinetics of ebeiedinone had not been reported. In this paper, UPLC–MS/MS method was established to determine ebeiedinone in mouse