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attests to the danger of ayahuasca to public health. But the CSA needs to be seen as a political document that is subject to change and questioning. The recent discussions about psilocybin, MDMA, and other psychedelics make it clear how it is a document
). MDMA-Assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study . Nature Medicine , 27 ( 6 ), 1025 – 1033 . https://doi.org/10.1038/s41591-021-01336-3 . Mithoefer , M. C. , Mithoefer , A. T. , Feduccia , A. A
is certainly the domain of a philosopher, who can guide discussions to better help a patient connect with an existing, or newfound, system of values. The use of MDMA in couples' therapy provides a glimpse of how values can change. Such therapy may
recently defined by the journal Psychedelic Medicine as serotonergic agonists that expand brain network connectivity by activating 5-HT2A receptors. They include classic psychedelics (psilocybin, mescaline, DMT, and LSD) as well as ketamine and MDMA
mystical experiences and fewer challenging experiences after actual use. In a more recent report of MDMA users, Elmer, Vannoy, Studerus, and Lyubomirsky (2024) found significant differences by types of intentions for the majority of positive social
, N. , Eckert , A. , … Liechti , M. ( 2020 ). Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects . Neuropsychopharmacology , 45 ( 3 ), 462 – 471 . Johnson , M. W. , Garcia-Romeu , A. , Cosimano , M. P
, A. , Jerome , L. , Mithoefer , A. , Wagner , M. , Walsh , Z. , Hamilton , S. , Yazar-Klosinski , B. , Emerson , A. & Doblin , R. ( 2019 ). MDMA-Assisted psychotherapy for treatment of PTSD: Study design and rationale for phase 3
) reported on the efficacy of MDMA and psilocybin in treating symptoms of PTSD and depression, but noted that confounders, patient bias, and challenges associated with blinding remain. Recent articles provide a valuable analysis of methodological problems
“relive the drug taking experience in their imagination” ( Baumann, 1970 , p. 20) with similar findings indicated more recently in a group of 3,4-Methylenedioxymethamphetamine (MDMA) users ( Hastings, 2006 ) suggesting the re-accessing of psychedelic
, E. , & Marcela Ot’alora , G. ( 2013 ). A manual for MDMA-assisted psychotherapy in the treatment of posttraumatic stress disorder . Priest , G. , Tanaka , K. , & Weber , Z. ( 1996 ). Paraconsistent logic . Roseman , L. , Nutt , D. J
