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= 0.4   m m . A full factorial design of experiment table was then constructed by choosing three

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, J. Combination of partial least squares regression and design of experiments to model the retention of pharmaceutical compounds in supercritical fluid chromatography . J. Chrom. A . 2017 , 1491 , 182 – 194 . 10.1016/j.chroma.2017.02.030 42

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agent (such as lactic acid or lactic acid bacteria) in the precipitation stage to also enhance the techno functional attributes of the obtained protein products. For this purpose, a design of experiments was adopted which included 12 experimental runs in

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and their applications in pharmaceutical product development . In: Design of experiments for pharmaceutical product development, volume I: basics and fundamental principles , pp. 77 – 85 . https://doi.org/10.1007/978-981-33-4717-5_7 . Cahyani , I

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