Search Results
A termékenységtudatosságon alapuló módszerek lehetőségei a családtervezésben
The possibilities of fertility awareness methods in family planning
. Assisted reproductive technology in Europe, 2013: results generated from European registers by ESHRE. Hum Reprod. 2017; 32: 1957–1973. 4 Carson SA
, trimethoprim-sulfamethoxazole, and colistin. Whole-genome sequencing The whole-genome sequencing was performed using DNA nanoball sequencing technology as previously described [ 8 ]. In brief, genomic DNA isolated from Kae1177-1bg was randomly size fragmented
of CL was confirmed by the presence of amastigotes in Giemsa-stained smears. In order to determine drug sensitivity, amastigotes were cultured in Novy-MacNeal-Nicolle (NNN) medium and RPMI 1640 media (Gibco, Life Technologies GmbH, Germany
A bioluminescent derivative of Bacillus subtilis containing a plasmid encoding a luxAB fusion under control of a vegetative promoter and gives bioluminescence upon addition of an exogenous long-chain aldehyde has been used as test organism. Its spore populations have been produced and their heat- and radiation survival curves established. Heat-sensitization effect of pre-irradiation of spores was proven not only by colony counting but also with differential scanning calorimetry. Under a linearly programmed temperature increase, the heat destruction of spores surviving 2.5 kGy gamma irradiation resulted in at a few centigrade lower temperature than that of untreated spores. Heat denaturation endotherms in the DSC-thermogram of irradiated spores were shifted to lower temperatures as well. Comparative turbidimetric, luminometric and phase-contrast microscopic studies of untreated, heat-treated and irradiated spore populations showed that the kinetics of germination and the light emission during germination of radiation-inactivated spores were the same as those of untreated spores, revealing that the pre-formed luciferase enzyme packaged into the spores during sporulation remained intact after an irradiation dose causing 90% decrease in number of colony forming spores. Therefore, in contrast to heat-treated spores, the initial bioluminescence reading upon germination of irradiated spores does not reflect the viable count of their population.
Abstract
Flow diverters (FDs) have been successfully applied in the recent decade to the treatment of intracranial aneurysms by impairing the communication between the flows in the parent artery and the aneurysm and, thus, the blood within the aneurysm sac. It would be desirable to have a simple and accurate computational method to follow the changes in the peri- and intraaneurysmal flow caused by the presence of FDs. The detailed flow simulation around the intricate wire structure of the FDs has three disadvantages: need for high amount of computational resources and highly skilled professionals to prepare the computational grid, and also the lack of validation that makes the invested effort questionable. In this paper, we propose a porous layer method to model the hydraulic resistance (HR) of one or several layers of the FDs. The basis of this proposal is twofold: first, from an application point of view, the only interesting parameter regarding the function of the FD is its HR; second, we have developed a method to measure the HR with a simple apparatus. We present the results of these measurements and demonstrate their utility in numerical simulations of patient-specific aneurysm simulations.
Abstract
Background and aims
This scoping review employed a multifaceted conceptualization of well-being to examine how psilocybin use affects well-being and related sub-concepts in healthy individuals. It investigated which factors influence the relationship between psilocybin use and well-being, what research protocols have been employed, and what underlying mechanisms have been proposed in existing studies.
Methods
A comprehensive literature search in line with the PRISMA guidelines was conducted. Scopus, PubMed, PsycINFO, Web of Science, and Google Scholar were searched for peer-reviewed articles about psilocybin and well-being in healthy populations.
Results
Studies were heterogeneous in regard to study objectives, study design, study procedure, sample size and psilocybin dosage. In all studies, psilocybin use led to positive well-being-related outcomes for the majority of participants. Facets of well-being positively affected by psilocybin use in this review were self-acceptance, positive relationships, and meaning/purpose in life.
Conclusions
This scoping review provided preliminary evidence for the beneficial effects of psilocybin on well-being and related sub-concepts such as self-acceptance, positive relationships, and meaning/purpose in life in healthy individuals. Ego-dissolution, unity, connectedness, and mystical-type experiences are interrelated concepts that seem to be crucial for explaining such positive well-being-related effects of psilocybin. Under conducive conditions, the use of psilocybin may contribute to healthy functioning, through broad and sustained improvements in a variety of well-being concepts. Due to the heterogeneous nature of the studies, more definite conclusions require further research with a rigorous and homogeneous design.
Arterial thrombosis is extremely rare in patients with factor V Leiden (FVL) mutation. Recent advances in multislice computed tomography (MSCT) technology facilitated diagnosis of thromboembolic events accurately without delay. We report a patient with FVL mutation and acute bilateral lower extremity deep venous thromboses, pulmonary thromboembolism, and acute left anterior descending artery thrombosis, all diagnosed by MSCT. MSCT has been utilized for prompt diagnosis of the concomitant thrombotic pathologies simultaneously.
Mesterséges intelligencia alkalmazása fogászati cone-beam számítógépes tomográfiás felvételek automatikus szegmentációjára
Automatic segmentation of dental cone-beam computed tomography scans using a deep learning framework
tapasztalatok.] Orv Hetil. 2019; 160: 1967–1975. [Hungrian] 25 Barabás JI, Palkovics D, Bognár V, et al. The role of 3D technology in the support of
A digitális technológia kínálta új lehetőségek a melanoma malignum szűrésében.
Szakirodalmi áttekintés
New opportunities offered by digital technology in melanoma malignum screening.
A literature review
surveillance of cutaneous malignancies. Am J Med. 2020; 133: 417–423. 46 Young AT, Vora NB, Cortez J, et al. The role of technology in melanoma screening and
A gerincvelői izomsorvadás újszülöttkori szűrésének eredményei Magyarországon 2023-ban
Results of neonatal screening for spinal muscular atrophy in Hungary in 2023
technology evaluation 15. Pharmacoecon Open 2023; 7: 863–875. Erratum: Pharmacoecon Open 2023; 7: 1015. 5 Crawford TO, Swoboda KJ, DeVivo DC, et al