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 1. Summary of results Code System Frequency DBT/MDMA-AT overlap 83 Concerns for MDMA-AT for BPD (+) 15 Modification for BPD Dx 5 Regression 4 Limitations of DBT/MDMA-AT treatment alone 0 Limitations of traditional treatment modalities (not/MDMA

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/Self-Validation 4 Emotional Dysregulation 6 Understanding Emotions 4 Emotional Self-Validation 7 Wise Mind 2 Support Network 5 Stigma-Lack of Access 10 De-Stigmatization 2 Lack of Access 5 Phase 2-MDMA-AT 0 MDMA Therapy Orientation 6 Therapist Role 2 Suicidality 5

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Multidisciplinary Association for Psychedelic Studies (MAPS) and MAPS Public Benefit Corporation (MAPS PBC) have been at the forefront of addressing PTSD by working to make 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy into a legal prescription

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Introduction ±3,4-Methylenedioxymethamphetamine (MDMA), the active ingredient of the street drug Ecstasy, was studied initially as an adjunct psychotherapeutic tool, prior to its nationwide prohibition. It was first termed

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psychotherapeutic and pharmacologic interventions, cases of full remission usually make up a minority of outcomes ( Alexander, 2012 ; Schottenbauer et al., 2008 ). The treatment modality of 3,4-Methylenedioxymethamphetamine-Assisted Therapy (MDMA-AT) for PTSD has

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people with various drug dependence, all which are described later. To date, 3,4,-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy research has focused primarily on post-traumatic stress disorder (PTSD). However, MDMA has never been explored as

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,4-methylenedioxymethamphetamine (MDMA) being used for a variety of indications ( Costandi, 2014; Passie, 2018 ). Current clinical research is exploring the safety and efficacy of psychedelics for mental health disorders, such as posttraumatic stress disorder (PTSD), mood

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,4,-methylenedioxymethamphetamine (MDMA)-assisted therapist training program and have served as therapists with the MAPS-sponsored trials of MDMA-assisted treatment of PTSD at NYUSoM. Currently, both authors are also part of a team conducting a qualitative interview study of

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% ( n = 38) reported using LSD, 6% ( n = 6) reported using ketamine, 8% ( n = 8) reported mixing a psychedelic with another psychedelic or MDMA, 2% ( n = 2) reported using DMT, 1% ( n = 1) reported using ayahuasca and 1% ( n = 1) reported using 2

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for psychedelic-assisted treatments currently. For example, a recent Phase III trial of MDMA-assisted treatment for post-traumatic stress disorder represents years of herculean work performed in multiple nations and reveals a promising effect size of

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