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Escherichia coli : simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model . J. Antimicrob. Chemother. 58 , 960 – 965 . 10.1093/jac/dkl356 Ogino , T. and Arai , T. ( 2007 ): Pharmacokinetic interactions of
Quirós, C., Herrero, M., García, L. A., et al.: Application of flow cytometry to segregated kinetic modeling based on the physiological states of microorganisms. Appl. Environ. Microbiol., 2007, 73 , 3993
-order (Equation 1 ), first-order (Equation 2 ), matrix (Higuchi model) (Equation 3 ), and Hixson–Crowell equations (Equation 4 ) to ascertain the kinetic modeling of drug release. Q t = k 0 t , (1) ln Q t = ln Q 0 − k 1 t , (2) Q t = k H t 1 / 2 , (3) Q 0 1
relaxation. Fig. 3. Various kinetic models and their R 2 value; (a) zero-order plot, (b) first order, (c) Higuchi, (d) Hixon–Crowell, and (e) Peppas model of formulation (ONbp
