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Journal of Behavioral Addictions
Authors:
Hyeonseok Jeong
,
Jin Kyoung Oh
,
Eun Kyoung Choi
,
Jooyeon Jamie Im
,
Sujung Yoon
,
Helena Knotkova
,
Marom Bikson
,
In-Uk Song
,
Sang Hoon Lee
, and
Yong-An Chung

., 2008; Fregni et al., 2008; Sauvaget et al., 2015 ). Positron emission tomography (PET) has unique potential for assessing cerebral metabolism, neuroreceptor occupancy, and neurotransmitter binding in vivo. In particular, mapping uptake of 18 F-fluoro-2

Open access
Journal of Behavioral Addictions
Authors:
Thomas McLaughlin
,
Kenneth Blum
,
Marlene Oscar-Berman
,
Marcelo Febo
,
Gozde Agan
,
James L. Fratantonio
,
Thomas Simpatico
, and
Mark S. Gold

factor analysis of rCBF data measured with SPECT . Journal of Cerebral Blood Flow & Metabolism , 12 ( 4 ), 535 – 545 Mellman , T. A. , David , D. , Kulick-Bell , R. , Hebding

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) identified IM as the most favorable route of administration of 5-MeO-DMT for the following reasons; it avoids first pass metabolism, has high bioavailability, precise control of dosage, and evokes a gentle onset with slightly longer duration of effects. This

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and Human Behavior , 33 ( 6 ), 708 – 714 . Rebuffe-Scrive , M. ( 1987 ). Regional adipose-tissue metabolism in men and in women during menstrual-cycle, pregnancy, lactation, and menopause . International Journal of Obesity , 11 , 1 . Rhodes

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variants mean that up to 10% of Caucasians lack the gene to synthesise the enzyme to metabolise ibogaine ( Meyer, Skoda, & Zanger, 1990 ). This can result in these individuals having plasma levels that double the levels of those with normal p450 metabolism

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Journal of Psychedelic Studies
Authors:
Thais Guimarães Bourscheid
,
Leonardo Corrêa Cardoso
,
Marcelo Henrique Nascimento Santana
,
Letícia Cimó de Oliveira
,
Fernanda Ziegler Reginato
,
Michel Mansur Machado
, and
André Valle de Bairros

of decarboxylated or partially carboxylated proteins ( Teles, Fukuda, & Feder, 2012 ). The absorption through the nasal mucosa probably does not trigger this type of metabolism and/or the amount of these compounds are not capable of promoting the

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Journal of Psychedelic Studies
Authors:
Cody Sykes Gilbert
,
Mitch Earleywine
,
Maha N. Mian
, and
Brianna R. Altman

0033291718001356 Papaseit , E. , Pérez-Mañá , C. , Torrens , M. , Farré , A. , Poyatos , L. , Hladun , O. , ( 2020 ). MDMA interactions with pharmaceuticals and drugs of abuse . Expert Opinion on Drug Metabolism and Toxicology , 16 ( 5 ), 357 - 369

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resting cerebral blood flow and metabolism in obsessive compulsive disorder: A meta-analysis . Scientific Reports , 7 ( 1 ), 17464 . 10.1038/s41598-017-17593-7 Vollenweider , F. X. , & Geyer , M. A. ( 2001 ). A systems model of altered

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. , & Mash , D. C. ( 1998 ). Cytochrome P4502D6 catalyses the o-demethylation of the psychoactive alkaloid ibogaine to 12-hydroxyibogamine . Drug Metabolism and Disposition , 26 ( 8 ), 764 – 768 . Ott , J. ( 1996 ). Entheogens II: On entheology and

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.drugalcdep.2017.09.011 Papaseit , E. , Torrens , M. , Pérez-Mañá , C. , Muga , R. , & Farré , M. ( 2018 ). Key interindividual determinants in MDMA pharmacodynamics . Expert Opinion on Drug Metabolism & Toxicology , 14 ( 2 ), 183 – 195 . https

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