A method for the determination of uranium and 210Po in high salinity water samples has been elaborated. Both radionuclides are preconcentrated from 0.5 dm3 saline media by co-precipitation with hydrated manganese dioxide, followed by dissolution of the precipitate in 200 mL of
1 M HCl. Uranium isotopes 235U and 238U can be directly determined by ICP MS method with a detection limit of 0.01 ppb for 238U. Prior to a selective determination of 210Po, the majority of other naturally occurring α-emitting radionuclides (uranium, thorium and protactinium) can be stripped
from this solution by their extraction with a 50% solution of HDEHP in toluene. Finally, 210Po is simply separated by direct transfer to an extractive scintillator containing 5% of trioctylphosphine oxide in Ultima
Gold F cocktail and determined by an α/β separation liquid scintillation technique with detection limit below 0.1 mBq/dm3.
Authors:Erdal Aktürk, Lütfü Aşkın, Hakan Taşolar, Ertuğrul Kurtoğlu, Serdar Türkmen, Okan Tanrıverdi, and Kader Eliz Uzel
study, patients with CTO who were treated with PCI were randomized into two groups with the intention to investigate CIN development, which is an important cause of morbidity/mortality. The first group underwent standard saline infusion as recommended in
or saline. A small test injection was not informative and was followed by ST segment elevation noticed on the ECG monitor while the patient started complaining of precordial chest pain. On a second injection, the angiographic picture was that of
Authors:Mahmood Al Ramahi, Sándor Beszédes, and Gábor Keszthelyi-Szabó
, Hungary. Standard error is shown in parentheses. Statistical differences are indicated by different superscript letters. On another note, the salinity of wastewater represented by EC was relatively low (<2.5), and pH values were within the acceptable range
Authors:Ziya Totonchi, Shirin Salajegheh, Mahmoud Reza Mohaghegh, MehrdadMesbah Kiaei, Mohammad Shirvani, and Masoud Ghorbanlo
were administered 1.5 mg/kg of 1% lidocaine 90 s before aortic cannulation (KINGODIC; 1% lidocaine, Caspian Tamin Pharmaceutical, Rasht, Iran), and patients in the placebo group received normal saline. All patients with SBP less than 110 mmHg were
Authors:Jinzhao Yang, Huamin Liu, Yuan Cai, Yazhen Wu, Xiaoxin Xu, Xianqin Wang, and Chongliang Lin
, continued for 14 days; the rats in control group were given Stroke-physiological saline solution (1 mL/100 g) by oral administration each day, continued for 14 days. The rats of two groups received a single oral administration of erlotinib (20 mg/kg) on the
Authors:Z. Stefanowicz, M. Sobczak, A. Piętniewicz, and W.L. Kołodziejski
Biodegradable and bioresorbable macromolecular conjugates of paclitaxel were prepared. The release of drug from conjugates has been carried out in vitro at 37 °C in phosphate buffered saline solution (PBS, pH 7.4), with 0.1% (w/v) Cremophor® EL. Periodically, all the solution in the samples was removed and replaced with fresh buffer until limit of detection (LOD) of paclitaxel was released. The quantity of released drug was analyzed by means of high-performance liquid chromatography (HPLC) method. Chromatographic separations were conducted using the NUCLEODUR C18 Gravity column with a guard column at 30 °C. Mobile phase consisted of a mixture of acetonitrile, methanol, and deionized water (60:2:38). The flow rate was 1.0 mL min−1, and paclitaxel was detected at 229 nm, retention time of 3.5 min. The applied analytical method was validated according to International Conference on Harmonization (ICH) procedures or recommendations. The chromatographic separation was excellent. The linearity in the range 0.1–4.5 μg mL−1 was found to be very good (R2 = 0.9999). LOD and limit of quantification (LOQ) were calculated to be 0.023 μg mL−1 and 0.068 μg mL−1, respectively. The release profiles were evaluated and compared. The process of paclitaxel release from Paclcon-2 conjugate seems to be the most interesting. Paclitaxel is released the longest and the most evenly.
,000) contained 50% water; the dose was calculated to dry matter. Both inducers and inhibitors were dissolved in physiological saline. ConA was dissolved immediately before each experiment. Indomethacine was first solubilized with Trisma, then a drop of Tween 80