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References 1. Campbell DJ , Debes GF , Johnston B , Wilson E , Butcher EC. : Targeting T cell responses by selective chemokine
References 1. Brownlie RJ , Zamoyska R : T cell receptor signalling networks: branched, diversified and bounded . Nat Rev Immunol 13
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Introduction Regulatory T cells (Tregs) are central players to confer tolerance towards self and harmless foreign antigens. They are characterized by expression of the lineage-specification transcription factor forkhead box protein P3 (Foxp3
, Bumann D , Epple HJ , Metzger W , Schneider T , Cherepnev G , Walduck AK , Kunkel D , Moos V , Loddenkemper C , Jiadze I , Panasyuk M , Stolte M , Graham DY , Zeitz M , Meyer TF : Correlation of T cell response and bacterial clearance in
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, Karp CL , Braciale TJ : Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10 . Nat Med 15 , 277 – 284 ( 2009 ) 4. Betts
colitis by CD4+CD25+ regulatory T cells . J Immunol 170 , 3939 – 3943 ( 2003 ) 5. Powrie F : T cells in inflammatory bowel disease
molecules with lymphocyte function-associated antigen 3 in T-cell recognition of nominal antigen . Proc Natl Acad Sci U S A 87 , 2603 – 2607 ( 1990 ) 2. Langley
, neutrophils, macrophages, natural killer cells and γδ T cells are mobilized to control the bacterial growth at the initial stage [ 21–24 ]. Meanwhile, Lm infection induces an adaptive immune response through both CD4 + and CD8 + T cells, leading to a full